 Hyperalgesia
"Hyperalgesia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An increased sensation of pain or discomfort produced by mimimally noxious stimuli due to damage to soft tissue containing NOCICEPTORS or injury to a peripheral nerve.
| Descriptor ID |
D006930
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| MeSH Number(s) |
C10.597.751.791.400 C23.888.592.763.770.400
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| Concept/Terms |
Hyperalgesia- Hyperalgesia
- Hyperalgesias
- Hyperalgesic Sensations
Mechanical Allodynia- Mechanical Allodynia
- Allodynias, Mechanical
- Hyperalgesia, Mechanical
- Hyperalgesias, Mechanical
- Mechanical Hyperalgesia
- Allodynia, Mechanical
Tactile Allodynia- Tactile Allodynia
- Allodynias, Tactile
- Hyperalgesia, Tactile
- Hyperalgesias, Tactile
- Allodynia, Tactile
Hyperalgesia, Thermal- Hyperalgesia, Thermal
- Hyperalgesias, Thermal
- Thermal Hyperalgesia
- Thermal Allodynia
- Allodynia, Thermal
- Allodynias, Thermal
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Below are MeSH descriptors whose meaning is more general than "Hyperalgesia".
Below are MeSH descriptors whose meaning is more specific than "Hyperalgesia".
This graph shows the total number of publications written about "Hyperalgesia" by people in this website by year, and whether "Hyperalgesia" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 | | 1994 | 7 | 0 | 7 | | 1995 | 1 | 1 | 2 | | 1997 | 2 | 0 | 2 | | 1999 | 0 | 1 | 1 | | 2000 | 1 | 1 | 2 | | 2001 | 1 | 2 | 3 | | 2003 | 3 | 1 | 4 | | 2004 | 3 | 4 | 7 | | 2005 | 1 | 1 | 2 | | 2006 | 5 | 0 | 5 | | 2007 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 2 | 2 | 4 | | 2010 | 2 | 4 | 6 | | 2011 | 3 | 1 | 4 | | 2012 | 8 | 5 | 13 | | 2013 | 5 | 5 | 10 | | 2014 | 6 | 4 | 10 | | 2015 | 0 | 2 | 2 | | 2016 | 3 | 3 | 6 | | 2017 | 1 | 3 | 4 | | 2018 | 1 | 3 | 4 | | 2019 | 1 | 0 | 1 | | 2020 | 3 | 0 | 3 |
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Below are the most recent publications written about "Hyperalgesia" by people in Profiles.
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Dripps IJ, Bertels Z, Moye LS, Tipton AF, Siegersma K, Baca SM, Kieffer BL, Pradhan AA. Forebrain delta opioid receptors regulate the response of delta agonist in models of migraine and opioid-induced hyperalgesia. Sci Rep. 2020 10 19; 10(1):17629.
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Doyle TM, Janes K, Chen Z, Grace PM, Esposito E, Cuzzocrea S, Largent-Milnes TM, Neumann WL, Watkins LR, Spiegel S, Vanderah TW, Salvemini D. Activation of sphingosine-1-phosphate receptor subtype 1 in the central nervous system contributes to morphine-induced hyperalgesia and antinociceptive tolerance in rodents. Pain. 2020 09 01; 161(9):2107-2118.
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Xie AX, Madayag A, Minton SK, McCarthy KD, Malykhina AP. Sensory satellite glial Gq-GPCR activation alleviates inflammatory pain via peripheral adenosine 1 receptor activation. Sci Rep. 2020 08 25; 10(1):14181.
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Drummond PD, Morellini N, Visser E, Finch PM. Expression of Cutaneous Beta-2 Adrenoceptors Is Similar in Patients with Complex Regional Pain Syndrome and Pain-Free Controls. Pain Med. 2020 06 01; 21(6):1199-1207.
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Grace PM, Galer EL, Strand KA, Corrigan K, Berkelhammer D, Maier SF, Watkins LR. Repeated Morphine Prolongs Postoperative Pain in Male Rats. Anesth Analg. 2019 01; 128(1):161-167.
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Kwilasz AJ, Green Fulgham SM, Ellis A, Patel HP, Duran-Malle JC, Favret J, Harvey LO, Rieger J, Maier SF, Watkins LR. A single peri-sciatic nerve administration of the adenosine 2A receptor agonist ATL313 produces long-lasting anti-allodynia and anti-inflammatory effects in male rats. Brain Behav Immun. 2019 02; 76:116-125.
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Drummond PD, Morellini N, Finch PM, Birklein F, Knudsen LF. Complex regional pain syndrome: intradermal injection of phenylephrine evokes pain and hyperalgesia in a subgroup of patients with upregulated a1-adrenoceptors on dermal nerves. Pain. 2018 Nov; 159(11):2296-2305.
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Drummond PD, Finch PM, Birklein F, Stanton-Hicks M, Knudsen LF. Hemisensory disturbances in patients with complex regional pain syndrome. Pain. 2018 Sep; 159(9):1824-1832.
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Joksimovic SL, Joksimovic SM, Tesic V, García-Caballero A, Feseha S, Zamponi GW, Jevtovic-Todorovic V, Todorovic SM. Selective inhibition of CaV3.2 channels reverses hyperexcitability of peripheral nociceptors and alleviates postsurgical pain. Sci Signal. 2018 08 28; 11(545).
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Drummond PD, Bell A, Vo L. Painful stimulation of a sensitized site in the forearm inhibits ipsilateral trigeminal nociceptive blink reflexes. Exp Brain Res. 2018 Jul; 236(7):2097-2105.
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