 Allosteric Regulation
"Allosteric Regulation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The modification of the reactivity of ENZYMES by the binding of effectors to sites (ALLOSTERIC SITES) on the enzymes other than the substrate BINDING SITES.
| Descriptor ID |
D000494
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| MeSH Number(s) |
G02.111.044
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| Concept/Terms |
Allosteric Regulation- Allosteric Regulation
- Regulation, Allosteric
- Allosteric Regulations
- Regulations, Allosteric
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Below are MeSH descriptors whose meaning is more general than "Allosteric Regulation".
Below are MeSH descriptors whose meaning is more specific than "Allosteric Regulation".
This graph shows the total number of publications written about "Allosteric Regulation" by people in this website by year, and whether "Allosteric Regulation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 2 | 2 | | 2001 | 0 | 1 | 1 | | 2002 | 0 | 2 | 2 | | 2005 | 0 | 1 | 1 | | 2006 | 1 | 3 | 4 | | 2007 | 0 | 4 | 4 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 3 | 3 | | 2012 | 0 | 2 | 2 | | 2013 | 0 | 5 | 5 | | 2014 | 0 | 4 | 4 | | 2015 | 0 | 2 | 2 | | 2016 | 0 | 11 | 11 | | 2017 | 0 | 3 | 3 | | 2018 | 2 | 3 | 5 | | 2019 | 0 | 8 | 8 | | 2020 | 0 | 3 | 3 | | 2021 | 0 | 5 | 5 | | 2022 | 0 | 2 | 2 | | 2023 | 0 | 3 | 3 | | 2024 | 0 | 7 | 7 | | 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Allosteric Regulation" by people in Profiles.
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Singh S, Arya G, Mishra R, Singla S, Pratap A, Upadhayay K, Sharma M, Chaba R. Molecular mechanisms underlying allosteric behavior of Escherichia coli DgoR, a GntR/FadR family transcriptional regulator. Nucleic Acids Res. 2025 Jan 07; 53(1).
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Gentry RC, Ide NA, Comunale VM, Hartwick EW, Kinz-Thompson CD, Gonzalez RL. The mechanism of mRNA cap recognition. Nature. 2025 Jan; 637(8046):736-743.
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Lee E, Redzic JS, Eisenmesser EZ. Evolutionary Adaptations in Biliverdin Reductase B: Insights into Coenzyme Dynamics and Catalytic Efficiency. Int J Mol Sci. 2024 Dec 10; 25(24).
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Vaisar D, Ahn NG. Latent allosteric control of protein interactions by ATP-competitive kinase inhibitors. Curr Opin Struct Biol. 2024 Dec; 89:102935.
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Gardner L, Rossi J, Armstrong B, Muse M, LaVeck A, Blevins MA, Zhang L, Ford HL, Zhao R, Wang X. Rational Design of Novel Allosteric EYA2 Inhibitors as Potential Therapeutics for Multiple Brain Cancers. ChemMedChem. 2024 Sep 16; 19(18):e202400179.
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Labouesse MA, Wilhelm M, Kagiampaki Z, Yee AG, Denis R, Harada M, Gresch A, Marinescu AM, Otomo K, Curreli S, Serratosa Capdevila L, Zhou X, Cola RB, Ravotto L, Gl?ck C, Cherepanov S, Weber B, Zhou X, Katner J, Svensson KA, Fellin T, Trudeau LE, Ford CP, Sych Y, Patriarchi T. A chemogenetic approach for dopamine imaging with tunable sensitivity. Nat Commun. 2024 Jul 02; 15(1):5551.
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Acton OJ, Sheppard D, Kunzelmann S, Caswell SJ, Nans A, Burgess AJO, Kelly G, Morris ER, Rosenthal PB, Taylor IA. Platform-directed allostery and quaternary structure dynamics of SAMHD1 catalysis. Nat Commun. 2024 May 06; 15(1):3775.
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Mickus R, Ra?kevicius V, Sarapiniene I, Mikalayeva V, Prekeris R, Skeberdis VA. Phosphorylation-dependent allosteric regulation of Cx43 gap junction inhibitor potency. Biomed Pharmacother. 2024 May; 174:116550.
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Gates CA, Backos DS, Reigan P, Natale NR. The Lateral Metalation of Isoxazolo[3,4-d]pyridazinones towards Hit-to-Lead Development of Selective Positive Modulators of Metabotropic Glutamate Receptors. Molecules. 2023 Sep 25; 28(19).
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Zha J, Li Q, Liu X, Lin W, Wang T, Wei J, Zhang Z, Lu X, Wu J, Ni D, Song K, Zhang L, Lu X, Lu S, Zhang J. AlloReverse: multiscale understanding among hierarchical allosteric regulations. Nucleic Acids Res. 2023 07 05; 51(W1):W33-W38.
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