 Uric Acid
"Uric Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
| Descriptor ID |
D014527
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| MeSH Number(s) |
D03.132.960.877 D03.633.100.759.758.824.877
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| Concept/Terms |
Uric Acid- Uric Acid
- Acid, Uric
- 2,6,8-Trihydroxypurine
- Trioxopurine
Sodium Urate Monohydrate- Sodium Urate Monohydrate
- Monohydrate, Sodium Urate
- Urate Monohydrate, Sodium
- Monosodium Urate Monohydrate
- Monohydrate, Monosodium Urate
- Urate Monohydrate, Monosodium
- Sodium Acid Urate Monohydrate
- Sodium Urate
- Urate, Sodium
- Monosodium Urate
- Urate, Monosodium
- Sodium Acid Urate
- Acid Urate, Sodium
- Urate, Sodium Acid
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Below are MeSH descriptors whose meaning is more general than "Uric Acid".
Below are MeSH descriptors whose meaning is more specific than "Uric Acid".
This graph shows the total number of publications written about "Uric Acid" by people in this website by year, and whether "Uric Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1995 | 0 | 1 | 1 | | 2000 | 2 | 0 | 2 | | 2002 | 5 | 0 | 5 | | 2003 | 4 | 3 | 7 | | 2004 | 3 | 4 | 7 | | 2005 | 6 | 3 | 9 | | 2006 | 12 | 2 | 14 | | 2007 | 4 | 3 | 7 | | 2008 | 12 | 1 | 13 | | 2009 | 10 | 3 | 13 | | 2010 | 6 | 4 | 10 | | 2011 | 11 | 8 | 19 | | 2012 | 13 | 4 | 17 | | 2013 | 12 | 5 | 17 | | 2014 | 9 | 4 | 13 | | 2015 | 11 | 3 | 14 | | 2016 | 10 | 3 | 13 | | 2017 | 6 | 3 | 9 | | 2018 | 4 | 2 | 6 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Uric Acid" by people in Profiles.
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Sanchez-Lozada LG, Andres-Hernando A, Garcia-Arroyo FE, Cicerchi C, Li N, Kuwabara M, Roncal-Jimenez CA, Johnson RJ, Lanaspa MA. Uric acid activates aldose reductase and the polyol pathway for endogenous fructose and fat production causing development of fatty liver in rats. J Biol Chem. 2019 03 15; 294(11):4272-4281.
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Andrews ES, Perrenoud L, Nowak KL, You Z, Pasch A, Chonchol M, Kendrick J, Jalal D. Examining the effects of uric acid-lowering on markers vascular of calcification and CKD-MBD; A post-hoc analysis of a randomized clinical trial. PLoS One. 2018; 13(10):e0205831.
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García-Arroyo FE, Gonzaga G, Muñoz-Jiménez I, Blas-Marron MG, Silverio O, Tapia E, Soto V, Ranganathan N, Ranganathan P, Vyas U, Irvin A, Ir D, Robertson CE, Frank DN, Johnson RJ, Sánchez-Lozada LG. Probiotic supplements prevented oxonic acid-induced hyperuricemia and renal damage. PLoS One. 2018; 13(8):e0202901.
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Kuwabara M, Kuwabara R, Niwa K, Hisatome I, Smits G, Roncal-Jimenez CA, MacLean PS, Yracheta JM, Ohno M, Lanaspa MA, Johnson RJ, Jalal DI. Different Risk for Hypertension, Diabetes, Dyslipidemia, and Hyperuricemia According to Level of Body Mass Index in Japanese and American Subjects. Nutrients. 2018 Aug 03; 10(8).
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Bjornstad P, Maahs DM, Roncal CA, Snell-Bergeon JK, Shah VN, Milagres T, Ellis SL, Hatch M, Chung LT, Rewers MJ, Garg S, Cherney DZ, Pyle L, Nadeau KJ, Johnson RJ. Role of bicarbonate supplementation on urine uric acid crystals and diabetic tubulopathy in adults with type 1 diabetes. Diabetes Obes Metab. 2018 07; 20(7):1776-1780.
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Kuwabara M, Borghi C, Cicero AFG, Hisatome I, Niwa K, Ohno M, Johnson RJ, Lanaspa MA. Elevated serum uric acid increases risks for developing high LDL cholesterol and hypertriglyceridemia: A five-year cohort study in Japan. Int J Cardiol. 2018 06 15; 261:183-188.
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King C, Lanaspa MA, Jensen T, Tolan DR, Sánchez-Lozada LG, Johnson RJ. Uric Acid as a Cause of the Metabolic Syndrome. Contrib Nephrol. 2018; 192:88-102.
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Kuwabara M, Hisatome I, Niwa K, Hara S, Roncal-Jimenez CA, Bjornstad P, Nakagawa T, Andres-Hernando A, Sato Y, Jensen T, Garcia G, Rodriguez-Iturbe B, Ohno M, Lanaspa MA, Johnson RJ. Uric Acid Is a Strong Risk Marker for Developing Hypertension From Prehypertension: A 5-Year Japanese Cohort Study. Hypertension. 2018 01; 71(1):78-86.
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Todd AS, Walker RJ, MacGinley RJ, Kelly J, Merriman TR, Major TJ, Johnson RJ. Dietary Sodium Modifies Serum Uric Acid Concentrations in Humans. Am J Hypertens. 2017 Nov 06; 30(12):1196-1202.
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Kuwabara M, Kuwabara R, Hisatome I, Niwa K, Roncal-Jimenez CA, Bjornstad P, Andres-Hernando A, Sato Y, Jensen T, Garcia G, Ohno M, Hill JO, Lanaspa MA, Johnson RJ. "Metabolically Healthy" Obesity and Hyperuricemia Increase Risk for Hypertension and Diabetes: 5-year Japanese Cohort Study. Obesity (Silver Spring). 2017 11; 25(11):1997-2008.
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