 Endotoxemia
"Endotoxemia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.
| Descriptor ID |
D019446
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| MeSH Number(s) |
C01.539.757.100.275 C01.539.861.375 C23.550.470.790.500.100.275
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Endotoxemia".
Below are MeSH descriptors whose meaning is more specific than "Endotoxemia".
This graph shows the total number of publications written about "Endotoxemia" by people in this website by year, and whether "Endotoxemia" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 | | 1998 | 3 | 1 | 4 | | 1999 | 2 | 2 | 4 | | 2000 | 5 | 0 | 5 | | 2001 | 5 | 2 | 7 | | 2002 | 4 | 1 | 5 | | 2003 | 1 | 0 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 2 | 0 | 2 | | 2006 | 1 | 0 | 1 | | 2007 | 1 | 1 | 2 | | 2008 | 1 | 0 | 1 | | 2010 | 1 | 2 | 3 | | 2012 | 4 | 0 | 4 | | 2013 | 0 | 1 | 1 | | 2014 | 2 | 0 | 2 | | 2015 | 1 | 1 | 2 | | 2016 | 1 | 0 | 1 | | 2017 | 2 | 0 | 2 | | 2018 | 2 | 0 | 2 | | 2019 | 3 | 0 | 3 |
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Below are the most recent publications written about "Endotoxemia" by people in Profiles.
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Butler B, De Dios R, Nguyen L, McKenna S, Ghosh S, Wright CJ. Developmentally Regulated Innate Immune NF?B Signaling Mediates IL-1a Expression in the Perinatal Murine Lung. Front Immunol. 2019; 10:1555.
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Davidson JA, Urban TT, Tong S, Maddux A, Hill G, Frank BS, Watson JD, Jaggers J, Simões EAF, Wischmeyer P. Alkaline Phosphatase Activity and Endotoxemia After Infant Cardiothoracic Surgery. Shock. 2019 03; 51(3):328-336.
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Nguyen L, Sandoval J, De Dios R, Yihdego E, Zarate M, Castro O, McKenna S, Wright CJ. The hepatic innate immune response is lobe-specific in a murine model endotoxemia. Innate Immun. 2019 02; 25(2):144-154.
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Hippensteel JA, Shapiro NI, Schmidt EP. Challenging Dogma: The Value of Bolus Fluids in the Early Resuscitation of Hyperdynamic Sepsis. Am J Respir Crit Care Med. 2018 10 15; 198(8):981-983.
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McKenna S, Burey T, Sandoval J, Nguyen L, Castro O, Gudipati S, Gonzalez J, El Kasmi KC, Wright CJ. Immunotolerant p50/NF?B Signaling and Attenuated Hepatic IFNß Expression Increases Neonatal Sensitivity to Endotoxemia. Front Immunol. 2018; 9:2210.
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Call JA, Donet J, Martin KS, Sharma AK, Chen X, Zhang J, Cai J, Galarreta CA, Okutsu M, Du Z, Lira VA, Zhang M, Mehrad B, Annex BH, Klibanov AL, Bowler RP, Laubach VE, Peirce SM, Yan Z. Muscle-derived extracellular superoxide dismutase inhibits endothelial activation and protects against multiple organ dysfunction syndrome in mice. Free Radic Biol Med. 2017 12; 113:212-223.
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Hui H, Zhai Y, Ao L, Cleveland JC, Liu H, Fullerton DA, Meng X. Klotho suppresses the inflammatory responses and ameliorates cardiac dysfunction in aging endotoxemic mice. Oncotarget. 2017 Feb 28; 8(9):15663-15676.
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Li J, Zhai Y, Ao L, Hui H, Fullerton DA, Dinarello CA, Meng X. Interleukin-37 suppresses the inflammatory response to protect cardiac function in old endotoxemic mice. Cytokine. 2017 07; 95:55-63.
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McKenna S, Eckman M, Parker A, Bok R, Hurt KJ, Wright CJ. Perinatal Endotoxemia Induces Sustained Hepatic COX-2 Expression through an NF?B-Dependent Mechanism. J Innate Immun. 2016; 8(4):386-99.
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McKenna S, Gossling M, Bugarini A, Hill E, Anderson AL, Rancourt RC, Balasubramaniyan N, El Kasmi KC, Wright CJ. Endotoxemia Induces I?Bß/NF-?B-Dependent Endothelin-1 Expression in Hepatic Macrophages. J Immunol. 2015 Oct 15; 195(8):3866-79.
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