 Silicone Oils
"Silicone Oils" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Organic siloxanes which are polymerized to the oily stage. The oils have low surface tension and density less than 1. They are used in industrial applications and in the treatment of retinal detachment, complicated by proliferative vitreoretinopathy.
| Descriptor ID |
D012827
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| MeSH Number(s) |
D02.715.650.700.800 D05.750.900.850.950 D25.720.900.850.950 J01.637.051.720.900.850.950
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Silicone Oils".
Below are MeSH descriptors whose meaning is more specific than "Silicone Oils".
This graph shows the total number of publications written about "Silicone Oils" by people in this website by year, and whether "Silicone Oils" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 | | 2010 | 2 | 0 | 2 | | 2011 | 1 | 0 | 1 | | 2012 | 3 | 2 | 5 | | 2013 | 1 | 1 | 2 | | 2015 | 3 | 2 | 5 | | 2016 | 2 | 0 | 2 | | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Silicone Oils" by people in Profiles.
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Melo GB, da Cruz NFS, do Monte Agra LL, Emerson GG, Lima LH, Linkuviene V, Maia M, Farah ME, Carpenter JF, Rodrigues EB, Probst C. Silicone oil-free syringes, siliconized syringes and needles: quantitative assessment of silicone oil release with drugs used for intravitreal injection. Acta Ophthalmol. 2021 Dec; 99(8):e1366-e1374.
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do Monte Agra LL, da Cruz NFS, Linkuviene V, Carpenter JF, Farah ME, Melo GB, Maia M. High particle variability across siliconized and oil-free syringes and needles from the same lots. Sci Rep. 2021 02 25; 11(1):4645.
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Melo GB, Cruz NFSD, Emerson GG, Rezende FA, Meyer CH, Uchiyama S, Carpenter J, Shiroma HF, Farah ME, Maia M, Rodrigues EB. Critical analysis of techniques and materials used in devices, syringes, and needles used for intravitreal injections. Prog Retin Eye Res. 2021 01; 80:100862.
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Ueda T, Nakamura K, Abe Y, Carpenter JF. Effects of Product Handling Parameters on Particle Levels in a?Commercial Factor VIII Product: Impacts and Mitigation. J Pharm Sci. 2019 Jan; 108(1):775-786.
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Chisholm CF, Soucie KR, Song JS, Strauch P, Torres RM, Carpenter JF, Ragheb JA, Randolph TW. Immunogenicity of Structurally Perturbed Hen Egg Lysozyme Adsorbed to Silicone Oil Microdroplets in Wild-Type and Transgenic Mouse Models. J Pharm Sci. 2017 06; 106(6):1519-1527.
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Mehta SB, Carpenter JF, Randolph TW. Colloidal Instability Fosters Agglomeration of Subvisible Particles Created by Rupture of Gels of a Monoclonal Antibody Formed at Silicone Oil-Water Interfaces. J Pharm Sci. 2016 08; 105(8):2338-48.
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Chisholm CF, Baker AE, Soucie KR, Torres RM, Carpenter JF, Randolph TW. Silicone Oil Microdroplets Can Induce Antibody Responses Against Recombinant Murine Growth Hormone in Mice. J Pharm Sci. 2016 05; 105(5):1623-1632.
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Gerhardt A, Mcumber AC, Nguyen BH, Lewus R, Schwartz DK, Carpenter JF, Randolph TW. Surfactant Effects on Particle Generation in Antibody Formulations in Pre-filled Syringes. J Pharm Sci. 2015 Dec; 104(12):4056-4064.
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Chisholm CF, Nguyen BH, Soucie KR, Torres RM, Carpenter JF, Randolph TW. In Vivo Analysis of the Potency of Silicone Oil Microdroplets as Immunological Adjuvants in Protein Formulations. J Pharm Sci. 2015 Nov; 104(11):3681-3690.
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Shomali M, Tanriverdi S, Freitag AJ, Engert J, Winter G, Siedler M, Kaymakcalan Z, Carpenter JF, Randolph TW. Dose levels in particulate-containing formulations impact anti-drug antibody responses to murine monoclonal antibody in mice. J Pharm Sci. 2015 May; 104(5):1610-21.
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