 Leukotriene C4
"Leukotriene C4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some VASCULAR SMOOTH MUSCLE. (From Dictionary of Prostaglandins and Related Compounds, 1990)
| Descriptor ID |
D017997
|
| MeSH Number(s) |
D10.251.355.255.100.450.855.455 D10.251.355.310.166.887.855.455 D23.469.050.175.450.725.400
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Leukotriene C4".
Below are MeSH descriptors whose meaning is more specific than "Leukotriene C4".
This graph shows the total number of publications written about "Leukotriene C4" by people in this website by year, and whether "Leukotriene C4" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 | | 1996 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 2000 | 1 | 2 | 3 | | 2007 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Leukotriene C4" by people in Profiles.
-
Murphy RC, Hammarstr?m S, Samuelsson B. Pillars Article: Leukotriene C: A Slow-Reacting Substance from Murine Mastocytoma Cells. Proc. Natl. Acad. Sci. USA. 1979. 76: 4275-4279. J Immunol. 2018 03 01; 200(5):1538-1542.
-
Suram S, Silveira LJ, Mahaffey S, Brown GD, Bonventre JV, Williams DL, Gow NA, Bratton DL, Murphy RC, Leslie CC. Cytosolic phospholipase A(2)a and eicosanoids regulate expression of genes in macrophages involved in host defense and inflammation. PLoS One. 2013; 8(7):e69002.
-
Eun JC, Moore EE, Mauchley DC, Johnson CA, Meng X, Banerjee A, Wohlauer MV, Zarini S, Gij?n MA, Murphy RC. The 5-lipoxygenase pathway is required for acute lung injury following hemorrhagic shock. Shock. 2012 Jun; 37(6):599-604.
-
Farias S, Frey LC, Murphy RC, Heidenreich KA. Injury-related production of cysteinyl leukotrienes contributes to brain damage following experimental traumatic brain injury. J Neurotrauma. 2009 Nov; 26(11):1977-86.
-
Farias SE, Zarini S, Precht T, Murphy RC, Heidenreich KA. Transcellular biosynthesis of cysteinyl leukotrienes in rat neuronal and glial cells. J Neurochem. 2007 Nov; 103(4):1310-8.
-
Bowers RC, Hevko J, Henson PM, Murphy RC. A novel glutathione containing eicosanoid (FOG7) chemotactic for human granulocytes. J Biol Chem. 2000 Sep 29; 275(39):29931-4.
-
Vidal A, Durand T, Vidal JP, Rossi JC, Ravasi S, Zarini S, Sala A. Synthesis of 19-[(2-azido-5-iodo)-benzoyloxy]-LTA4 and enzymatic conversion to the LTC4 analogue. Bioorg Med Chem Lett. 2000 Apr 03; 10(7):665-8.
-
Douglas IS, Leff AR, Sperling AI. CD4+ T cell and eosinophil adhesion is mediated by specific ICAM-3 ligation and results in eosinophil activation. J Immunol. 2000 Mar 15; 164(6):3385-91.
-
Fadok VA, Bratton DL, Konowal A, Freed PW, Westcott JY, Henson PM. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J Clin Invest. 1998 Feb 15; 101(4):890-8.
-
Henderson WR, Lewis DB, Albert RK, Zhang Y, Lamm WJ, Chiang GK, Jones F, Eriksen P, Tien YT, Jonas M, Chi EY. The importance of leukotrienes in airway inflammation in a mouse model of asthma. J Exp Med. 1996 Oct 01; 184(4):1483-94.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|