 Macrophages
"Macrophages" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.)
| Descriptor ID |
D008264
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| MeSH Number(s) |
A11.329.372 A11.627.482 A11.733.397 A15.382.680.397 A15.382.812.522
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| Concept/Terms |
Macrophages- Macrophages
- Bone Marrow-Derived Macrophages
- Bone Marrow Derived Macrophages
- Bone Marrow-Derived Macrophage
- Macrophage, Bone Marrow-Derived
- Macrophages, Bone Marrow-Derived
- Monocyte-Derived Macrophages
- Monocyte Derived Macrophages
- Macrophage
- Macrophages, Monocyte-Derived
- Macrophage, Monocyte-Derived
- Macrophages, Monocyte Derived
- Monocyte-Derived Macrophage
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Below are MeSH descriptors whose meaning is more general than "Macrophages".
Below are MeSH descriptors whose meaning is more specific than "Macrophages".
This graph shows the total number of publications written about "Macrophages" by people in this website by year, and whether "Macrophages" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 6 | 0 | 6 | | 1994 | 5 | 5 | 10 | | 1995 | 5 | 3 | 8 | | 1996 | 1 | 4 | 5 | | 1997 | 4 | 1 | 5 | | 1998 | 6 | 6 | 12 | | 1999 | 2 | 6 | 8 | | 2000 | 4 | 6 | 10 | | 2001 | 11 | 5 | 16 | | 2002 | 10 | 13 | 23 | | 2003 | 9 | 10 | 19 | | 2004 | 6 | 15 | 21 | | 2005 | 7 | 12 | 19 | | 2006 | 16 | 16 | 32 | | 2007 | 18 | 23 | 41 | | 2008 | 18 | 22 | 40 | | 2009 | 11 | 21 | 32 | | 2010 | 18 | 16 | 34 | | 2011 | 19 | 23 | 42 | | 2012 | 26 | 11 | 37 | | 2013 | 16 | 21 | 37 | | 2014 | 18 | 17 | 35 | | 2015 | 20 | 18 | 38 | | 2016 | 15 | 21 | 36 | | 2017 | 16 | 17 | 33 | | 2018 | 18 | 16 | 34 | | 2019 | 19 | 15 | 34 | | 2020 | 18 | 22 | 40 | | 2021 | 15 | 12 | 27 | | 2022 | 2 | 6 | 8 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Macrophages" by people in Profiles.
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Fritz D, Inamo J, Zhang F. Single-cell computational machine learning approaches to immune-mediated inflammatory disease: New tools uncover novel fibroblast and macrophage interactions driving pathogenesis. Front Immunol. 2022; 13:1076700.
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Kim JS, Liu L, Davenport B, Kant S, Morrison TE, Vazquez-Torres A. Oxidative stress activates transcription of Salmonella pathogenicity island-2 genes in macrophages. J Biol Chem. 2022 07; 298(7):102130.
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Konigsberg IR, Yang IV. Differential Methylation of Chronic Obstructive Pulmonary Disease Lung Macrophage Genes Sheds Light on Disease Pathogenesis. Am J Respir Cell Mol Biol. 2022 06; 66(6):589-590.
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Campbell NV, Mickael C, Kumar S, Zhang H, Campbell IL, Gillen AE, Trentin CO, Diener K, Gao B, Kheyfets VO, Gu S, Kumar R, Phang T, Brown RD, Graham BB, Stenmark KR. Single-cell RNA sequencing and binary hierarchical clustering define lung interstitial macrophage heterogeneity in response to hypoxia. Am J Physiol Lung Cell Mol Physiol. 2022 07 01; 323(1):L58-L68.
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El Kharbili M, Aviszus K, Sasse SK, Zhao X, Serban KA, Majka SM, Gerber AN, Gally F. Macrophage programming is regulated by a cooperative interaction between fatty acid binding protein 5 and peroxisome proliferator-activated receptor ?. FASEB J. 2022 05; 36(5):e22300.
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Ferrero E, Villa A, Stefanoni D, Nemkov T, D'Alessandro A, Tengesdal I, Belloni D, Molteni R, Vergani B, De Luca G, Grassini G, Cangi MG, Dagna L, Doglioni C, Cavalli G, Ferrarini M. Immunometabolic activation of macrophages leads to cytokine production in the pathogenesis of KRAS-mutated histiocytosis. Rheumatology (Oxford). 2022 04 11; 61(4):e93-e96.
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Gibbings SL, Haist KC, Nick H, Frasch SC, Glass TH, Vestal B, Danhorn T, Mould KJ, Henson PM, Bratton DL. Heightened turnover and failed maturation of monocyte-derived macrophages in murine chronic granulomatous disease. Blood. 2022 03 17; 139(11):1707-1721.
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Saleh LS, Amer LD, Thompson BJ, Danhorn T, Knapp JR, Gibbings SL, Thomas S, Barthel L, O'Connor BP, Janssen WJ, Alper S, Bryant SJ. Mapping Macrophage Polarization and Origin during the Progression of the Foreign Body Response to a Poly(ethylene glycol) Hydrogel Implant. Adv Healthc Mater. 2022 05; 11(9):e2102209.
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McCubbrey AL, McManus SA, McClendon JD, Thomas SM, Chatwin HB, Reisz JA, D'Alessandro A, Mould KJ, Bratton DL, Henson PM, Janssen WJ. Polyamine import and accumulation causes immunomodulation in macrophages engulfing apoptotic cells. Cell Rep. 2022 01 11; 38(2):110222.
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King EM, Hume PS, Janssen WJ, McCubbrey AL. Isolation and Analysis of Macrophage Subsets from the Mouse and Human Lung. Methods Mol Biol. 2022; 2506:257-267.
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