 Macrophages
"Macrophages" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.)
| Descriptor ID |
D008264
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| MeSH Number(s) |
A11.329.372 A11.627.482 A11.733.397 A15.382.680.397 A15.382.812.522
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| Concept/Terms |
Macrophages- Macrophages
- Bone Marrow-Derived Macrophages
- Bone Marrow Derived Macrophages
- Bone Marrow-Derived Macrophage
- Macrophage, Bone Marrow-Derived
- Macrophages, Bone Marrow-Derived
- Monocyte-Derived Macrophages
- Monocyte Derived Macrophages
- Macrophage
- Macrophages, Monocyte-Derived
- Macrophage, Monocyte-Derived
- Macrophages, Monocyte Derived
- Monocyte-Derived Macrophage
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Below are MeSH descriptors whose meaning is more general than "Macrophages".
Below are MeSH descriptors whose meaning is more specific than "Macrophages".
This graph shows the total number of publications written about "Macrophages" by people in this website by year, and whether "Macrophages" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 2 | 3 | 5 | | 1981 | 3 | 1 | 4 | | 1982 | 4 | 3 | 7 | | 1983 | 5 | 2 | 7 | | 1984 | 3 | 3 | 6 | | 1985 | 3 | 4 | 7 | | 1986 | 6 | 3 | 9 | | 1987 | 1 | 3 | 4 | | 1988 | 4 | 8 | 12 | | 1989 | 1 | 3 | 4 | | 1990 | 4 | 3 | 7 | | 1991 | 7 | 2 | 9 | | 1992 | 1 | 4 | 5 | | 1993 | 7 | 0 | 7 | | 1994 | 7 | 5 | 12 | | 1995 | 9 | 3 | 12 | | 1996 | 2 | 6 | 8 | | 1997 | 5 | 2 | 7 | | 1998 | 6 | 6 | 12 | | 1999 | 5 | 8 | 13 | | 2000 | 4 | 6 | 10 | | 2001 | 11 | 3 | 14 | | 2002 | 11 | 14 | 25 | | 2003 | 9 | 10 | 19 | | 2004 | 4 | 17 | 21 | | 2005 | 6 | 16 | 22 | | 2006 | 18 | 17 | 35 | | 2007 | 17 | 24 | 41 | | 2008 | 20 | 18 | 38 | | 2009 | 14 | 21 | 35 | | 2010 | 16 | 18 | 34 | | 2011 | 21 | 20 | 41 | | 2012 | 29 | 14 | 43 | | 2013 | 15 | 22 | 37 | | 2014 | 16 | 16 | 32 | | 2015 | 20 | 15 | 35 | | 2016 | 16 | 17 | 33 | | 2017 | 15 | 14 | 29 | | 2018 | 3 | 2 | 5 |
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Below are the most recent publications written about "Macrophages" by people in Profiles.
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Ziemba BP, Falke JJ. A PKC-MARCKS-PI3K regulatory module links Ca2+ and PIP3 signals at the leading edge of polarized macrophages. PLoS One. 2018; 13(5):e0196678.
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Chen S, Bonifati S, Qin Z, St Gelais C, Kodigepalli KM, Barrett BS, Kim SH, Antonucci JM, Ladner KJ, Buzovetsky O, Knecht KM, Xiong Y, Yount JS, Guttridge DC, Santiago ML, Wu L. SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-?B and interferon pathways. Proc Natl Acad Sci U S A. 2018 04 17; 115(16):E3798-E3807.
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Ruiz-Moreno JS, Hamann L, Jin L, Sander LE, Puzianowska-Kuznicka M, Cambier J, Witzenrath M, Schumann RR, Suttorp N, Opitz B. The cGAS/STING Pathway Detects Streptococcus pneumoniae but Appears Dispensable for Antipneumococcal Defense in Mice and Humans. Infect Immun. 2018 03; 86(3).
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Marchetti C, Swartzwelter B, Gamboni F, Neff CP, Richter K, Azam T, Carta S, Tengesdal I, Nemkov T, D'Alessandro A, Henry C, Jones GS, Goodrich SA, St Laurent JP, Jones TM, Scribner CL, Barrow RB, Altman RD, Skouras DB, Gattorno M, Grau V, Janciauskiene S, Rubartelli A, Joosten LAB, Dinarello CA. OLT1177, a ß-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation. Proc Natl Acad Sci U S A. 2018 02 13; 115(7):E1530-E1539.
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McCubbrey AL, Barthel L, Mohning MP, Redente EF, Mould KJ, Thomas SM, Leach SM, Danhorn T, Gibbings SL, Jakubzick CV, Henson PM, Janssen WJ. Deletion of c-FLIP from CD11bhi Macrophages Prevents Development of Bleomycin-induced Lung Fibrosis. Am J Respir Cell Mol Biol. 2018 01; 58(1):66-78.
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Sasidhar MV, Chevooru SK, Eickelberg O, Hartung HP, Neuhaus O. Downregulation of monocytic differentiation via modulation of CD147 by 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. PLoS One. 2017; 12(12):e0189701.
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Smith AJ, Graves B, Child R, Rice PJ, Ma Z, Lowman DW, Ensley HE, Ryter KT, Evans JT, Williams DL. Immunoregulatory Activity of the Natural Product Laminarin Varies Widely as a Result of Its Physical Properties. J Immunol. 2018 01 15; 200(2):788-799.
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Quick ED, Seitz S, Clarke P, Tyler KL. Minocycline Has Anti-inflammatory Effects and Reduces Cytotoxicity in an Ex Vivo Spinal Cord Slice Culture Model of West Nile Virus Infection. J Virol. 2017 11 15; 91(22).
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Kane SJ, Farley TK, Gordon EO, Estep J, Bender HR, Moreno JA, Bartz J, Telling GC, Pickering MC, Zabel MD. Complement Regulatory Protein Factor H Is a Soluble Prion Receptor That Potentiates Peripheral Prion Pathogenesis. J Immunol. 2017 12 01; 199(11):3821-3827.
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Wallace J, Lutgen V, Avasarala S, St Croix B, Winn RA, Al-Harthi L. Wnt7a induces a unique phenotype of monocyte-derived macrophages with lower phagocytic capacity and differential expression of pro- and anti-inflammatory cytokines. Immunology. 2018 02; 153(2):203-213.
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