 Brugada Syndrome
"Brugada Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autosomal dominant defect of cardiac conduction that is characterized by an abnormal ST-segment in leads V1-V3 on the ELECTROCARDIOGRAM resembling a right BUNDLE-BRANCH BLOCK; high risk of VENTRICULAR TACHYCARDIA; or VENTRICULAR FIBRILLATION; SYNCOPAL EPISODE; and possible sudden death. This syndrome is linked to mutations of gene encoding the cardiac SODIUM CHANNEL alpha subunit.
| Descriptor ID |
D053840
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| MeSH Number(s) |
C14.280.067.322 C14.280.123.250 C16.320.100
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| Concept/Terms |
Brugada Syndrome- Brugada Syndrome
- Sudden Unexplained Death Syndrome
- Brugada Syndrome 1
- Brugada Syndrome 1s
- Sudden Unexplained Nocturnal Death Syndrome
- Right Bundle Branch Block, ST Segment Elevation, and Sudden Death Syndrome
- Sudden Unexplained Nocturnal Death Syndrome (SUNDS)
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Below are MeSH descriptors whose meaning is more general than "Brugada Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Brugada Syndrome".
This graph shows the total number of publications written about "Brugada Syndrome" by people in this website by year, and whether "Brugada Syndrome" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 4 | 0 | 4 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 1 | 2 |
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Below are the most recent publications written about "Brugada Syndrome" by people in Profiles.
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Sanner K, Mueller-Leisse J, Zormpas C, Duncker D, Leffler A, Veltmann C. A Novel SCN5A Variant Causes Temperature-Sensitive Loss Of Function in a Family with Symptomatic Brugada Syndrome, Cardiac Conduction Disease, and Sick Sinus Syndrome. Cardiology. 2021; 146(6):754-762.
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Peters CH, Watkins AR, Poirier OL, Ruben PC. E1784K, the most common Brugada syndrome and long-QT syndrome type 3 mutant, disrupts sodium channel inactivation through two separate mechanisms. J Gen Physiol. 2020 09 07; 152(9).
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Shenasa M, Heidary S, Shenasa H. Inappropriate ICD shock due to hot tub-induced external electrical interference. J Electrocardiol. 2018 Sep - Oct; 51(5):852-855.
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Heath RR, Varosy PD, Katz DF, Schuller JL, Aleong RG, Sauer WH, Nguyen DT. Life-threatening ST-segment elevation without coronary artery disease. Arch Intern Med. 2011 May 09; 171(9):801, 802-3.
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Tzou WS, Gerstenfeld EP. Genetic testing in the management of inherited arrhythmia syndromes. Curr Cardiol Rep. 2009 Sep; 11(5):343-51.
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Ambardekar AV, Krantz MJ. The Brugada syndrome: the perfect storm of genetics and environment? Int J Cardiol. 2010 May 14; 141(1):108-9.
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Bebarta VS, Waksman JC. Reply to: "Amitriptyline-induced Brugada pattern fails to respond to sodium bicarbonate". Clin Toxicol (Phila). 2008 Jan; 46(1):90-1.
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Ambardekar AV, Lewkowiez L, Krantz MJ. Mastitis unmasks Brugada syndrome. Int J Cardiol. 2009 Mar 06; 132(3):e94-6.
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London B, Michalec M, Mehdi H, Zhu X, Kerchner L, Sanyal S, Viswanathan PC, Pfahnl AE, Shang LL, Madhusudanan M, Baty CJ, Lagana S, Aleong R, Gutmann R, Ackerman MJ, McNamara DM, Weiss R, Dudley SC. Mutation in glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) decreases cardiac Na+ current and causes inherited arrhythmias. Circulation. 2007 Nov 13; 116(20):2260-8.
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Bebarta VS, Phillips S, Eberhardt A, Calihan KJ, Waksman JC, Heard K. Incidence of Brugada electrocardiographic pattern and outcomes of these patients after intentional tricyclic antidepressant ingestion. Am J Cardiol. 2007 Aug 15; 100(4):656-60.
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