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Margaret A Schmitt

TitleResearch Associate
InstitutionUniversity of Colorado Denver - Denver Campus
DepartmentCLAS-Chemistry

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Tittle JM, Schwark DG, Biddle W, Schmitt MA, Fisk JD. Impact of queuosine modification of endogenous E. coli tRNAs on sense codon reassignment. Front Mol Biosci. 2022; 9:938114. PMID: 36120552.
      View in: PubMed
    2. Biddle W, Schwark DG, Schmitt MA, Fisk JD. Directed Evolution Pipeline for the Improvement of Orthogonal Translation Machinery for Genetic Code Expansion at Sense Codons. Front Chem. 2022; 10:815788. PMID: 35252113.
      View in: PubMed
    3. Schwark DG, Schmitt MA, Fisk JD. Directed Evolution of the Methanosarcina barkeri Pyrrolysyl tRNA/aminoacyl tRNA Synthetase Pair for Rapid Evaluation of Sense Codon Reassignment Potential. Int J Mol Sci. 2021 Jan 18; 22(2). PMID: 33477414.
      View in: PubMed
    4. Schwark DG, Schmitt MA, Biddle W, Fisk JD. The Influence of Competing tRNA Abundance on Translation: Quantifying the Efficiency of Sense Codon Reassignment at Rarely Used Codons. Chembiochem. 2020 08 17; 21(16):2274-2286. PMID: 32203635.
      View in: PubMed
    5. Schwark DG, Schmitt MA, Fisk JD. Dissecting the Contribution of Release Factor Interactions to Amber Stop Codon Reassignment Efficiencies of the Methanocaldococcus jannaschii Orthogonal Pair. Genes (Basel). 2018 Nov 12; 9(11). PMID: 30424562.
      View in: PubMed
    6. Schmitt MA, Biddle W, Fisk JD. Mapping the Plasticity of the Escherichia coli Genetic Code with Orthogonal Pair-Directed Sense Codon Reassignment. Biochemistry. 2018 05 15; 57(19):2762-2774. PMID: 29668270.
      View in: PubMed
    7. Zhao N, Spencer J, Schmitt MA, Fisk JD. Hyperthermostable binding molecules on phage: Assay components for point-of-care diagnostics for active tuberculosis infection. Anal Biochem. 2017 03 15; 521:59-71. PMID: 28062210.
      View in: PubMed
    8. Biddle W, Schmitt MA, Fisk JD. Modification of orthogonal tRNAs: unexpected consequences for sense codon reassignment. Nucleic Acids Res. 2016 12 01; 44(21):10042-10050. PMID: 27915288.
      View in: PubMed
    9. Smeal SW, Schmitt MA, Pereira RR, Prasad A, Fisk JD. Simulation of the M13 life cycle I: Assembly of a genetically-structured deterministic chemical kinetic simulation. Virology. 2017 01; 500:259-274. PMID: 27644585.
      View in: PubMed
    10. Smeal SW, Schmitt MA, Pereira RR, Prasad A, Fisk JD. Simulation of the M13 life cycle II: Investigation of the control mechanisms of M13 infection and establishment of the carrier state. Virology. 2017 01; 500:275-284. PMID: 27569186.
      View in: PubMed
    11. Zhao N, Schmitt MA, Fisk JD. Phage display selection of tight specific binding variants from a hyperthermostable Sso7d scaffold protein library. FEBS J. 2016 Apr; 283(7):1351-67. PMID: 26835881.
      View in: PubMed
    12. Biddle W, Schmitt MA, Fisk JD. Evaluating Sense Codon Reassignment with a Simple Fluorescence Screen. Biochemistry. 2015 Dec 22; 54(50):7355-64. PMID: 26536053.
      View in: PubMed
    13. Schmitt MA, Weisblum B, Gellman SH. Interplay among folding, sequence, and lipophilicity in the antibacterial and hemolytic activities of alpha/beta-peptides. J Am Chem Soc. 2007 Jan 17; 129(2):417-28. PMID: 17212422.
      View in: PubMed
    14. Fisk JD, Schmitt MA, Gellman SH. Thermodynamic analysis of autonomous parallel beta-sheet formation in water. J Am Chem Soc. 2006 Jun 07; 128(22):7148-9. PMID: 16734453.
      View in: PubMed
    15. Schmitt MA, Choi SH, Guzei IA, Gellman SH. New helical foldamers: heterogeneous backbones with 1:2 and 2:1 alpha:beta-amino acid residue patterns. J Am Chem Soc. 2006 Apr 12; 128(14):4538-9. PMID: 16594667.
      View in: PubMed
    16. Epand RF, Schmitt MA, Gellman SH, Epand RM. Role of membrane lipids in the mechanism of bacterial species selective toxicity by two alpha/beta-antimicrobial peptides. Biochim Biophys Acta. 2006 Sep; 1758(9):1343-50. PMID: 16564494.
      View in: PubMed
    17. Epand RF, Schmitt MA, Gellman SH, Sen A, Auger M, Hughes DW, Epand RM. Bacterial species selective toxicity of two isomeric alpha/beta-peptides: role of membrane lipids. Mol Membr Biol. 2005 Nov-Dec; 22(6):457-69. PMID: 16373318.
      View in: PubMed
    18. Schmitt MA, Choi SH, Guzei IA, Gellman SH. Residue requirements for helical folding in short alpha/beta-peptides: crystallographic characterization of the 11-helix in an optimized sequence. J Am Chem Soc. 2005 Sep 28; 127(38):13130-1. PMID: 16173725.
      View in: PubMed
    19. Sadowsky JD, Schmitt MA, Lee HS, Umezawa N, Wang S, Tomita Y, Gellman SH. Chimeric (alpha/beta + alpha)-peptide ligands for the BH3-recognition cleft of Bcl-XL: critical role of the molecular scaffold in protein surface recognition. J Am Chem Soc. 2005 Aug 31; 127(34):11966-8. PMID: 16117535.
      View in: PubMed
    20. Schmitt MA, Weisblum B, Gellman SH. Unexpected relationships between structure and function in alpha,beta-peptides: antimicrobial foldamers with heterogeneous backbones. J Am Chem Soc. 2004 Jun 09; 126(22):6848-9. PMID: 15174837.
      View in: PubMed
    21. Hayen A, Schmitt MA, Ngassa FN, Thomasson KA, Gellman SH. Two helical conformations from a single foldamer backbone: "split personality" in short alpha/beta-peptides. Angew Chem Int Ed Engl. 2004 Jan 16; 43(4):505-10. PMID: 14735547.
      View in: PubMed
    22. Porter EA, Wang X, Schmitt MA, Gellman SH. Synthesis and 12-helical secondary structure of beta-peptides containing (2R,3R)-aminoproline. Org Lett. 2002 Sep 19; 4(19):3317-9. PMID: 12227778.
      View in: PubMed
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