 Amino Acid Transport System L
"Amino Acid Transport System L" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sodium-independent neutral amino acid transporter system with specificity for large amino acids. One of the functions of the transporter system is to supply large neutral amino acids to the brain.
| Descriptor ID |
D027062
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| MeSH Number(s) |
D12.776.157.530.200.500.500 D12.776.543.585.200.500.500
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| Concept/Terms |
Amino Acid Transport System L- Amino Acid Transport System L
- System L Transporter Proteins
- System L Transporter
- Transporter, System L
- Amino Acid Transport System L Proteins
- Large Neutral Amino Acid Transporter (LNAA)
- Large Amino Acid Transporter (LAT)
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Below are MeSH descriptors whose meaning is more general than "Amino Acid Transport System L".
Below are MeSH descriptors whose meaning is more specific than "Amino Acid Transport System L".
This graph shows the total number of publications written about "Amino Acid Transport System L" by people in this website by year, and whether "Amino Acid Transport System L" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2012 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Amino Acid Transport System L" by people in Profiles.
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Rosario FJ, Kramer A, Li C, Galan HL, Powell TL, Nathanielsz PW, Jansson T. Reduction of In Vivo Placental Amino Acid Transport Precedes the Development of Intrauterine Growth Restriction in the Non-Human Primate. Nutrients. 2021 Aug 23; 13(8).
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Vaughan OR, Powell TL, Jansson T. Apelin is a novel regulator of human trophoblast amino acid transport. Am J Physiol Endocrinol Metab. 2019 05 01; 316(5):E810-E816.
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Dosier LBM, Premkumar VJ, Zhu H, Akosman I, Wempe MF, McMahon TJ. Antagonists of the system L neutral amino acid transporter (LAT) promote endothelial adhesivity of human red blood cells. Thromb Haemost. 2017 06 28; 117(7):1402-1411.
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Gaccioli F, Aye IL, Roos S, Lager S, Ramirez VI, Kanai Y, Powell TL, Jansson T. Expression and functional characterisation of System L amino acid transporters in the human term placenta. Reprod Biol Endocrinol. 2015 Jun 09; 13:57.
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Yun DW, Lee SA, Park MG, Kim JS, Yu SK, Park MR, Kim SG, Oh JS, Kim CS, Kim HJ, Kim JS, Chun HS, Kanai Y, Endou H, Wempe MF, Kim DK. JPH203, an L-type amino acid transporter 1-selective compound, induces apoptosis of YD-38 human oral cancer cells. J Pharmacol Sci. 2014; 124(2):208-17.
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Aye IL, Jansson T, Powell TL. Interleukin-1? inhibits insulin signaling and prevents insulin-stimulated system A amino acid transport in primary human trophoblasts. Mol Cell Endocrinol. 2013 Dec 05; 381(1-2):46-55.
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Rosario FJ, Kanai Y, Powell TL, Jansson T. Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells. J Physiol. 2013 Feb 01; 591(3):609-25.
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Roos S, Kanai Y, Prasad PD, Powell TL, Jansson T. Regulation of placental amino acid transporter activity by mammalian target of rapamycin. Am J Physiol Cell Physiol. 2009 Jan; 296(1):C142-50.
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Roos S, Jansson N, Palmberg I, S?lj? K, Powell TL, Jansson T. Mammalian target of rapamycin in the human placenta regulates leucine transport and is down-regulated in restricted fetal growth. J Physiol. 2007 Jul 01; 582(Pt 1):449-59.
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