 RNA, Catalytic
"RNA, Catalytic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
RNA that has catalytic activity. The catalytic RNA sequence folds to form a complex surface that can function as an enzyme in reactions with itself and other molecules. It may function even in the absence of protein. There are numerous examples of RNA species that are acted upon by catalytic RNA, however the scope of this enzyme class is not limited to a particular type of substrate.
| Descriptor ID |
D016337
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| MeSH Number(s) |
D08.811.797 D13.444.735.790.199
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "RNA, Catalytic".
Below are MeSH descriptors whose meaning is more specific than "RNA, Catalytic".
This graph shows the total number of publications written about "RNA, Catalytic" by people in this website by year, and whether "RNA, Catalytic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 7 | 0 | 7 | | 1993 | 7 | 1 | 8 | | 1994 | 12 | 0 | 12 | | 1995 | 5 | 0 | 5 | | 1996 | 10 | 0 | 10 | | 1997 | 10 | 1 | 11 | | 1998 | 4 | 1 | 5 | | 1999 | 1 | 3 | 4 | | 2000 | 3 | 1 | 4 | | 2001 | 7 | 0 | 7 | | 2002 | 6 | 0 | 6 | | 2003 | 0 | 1 | 1 | | 2004 | 2 | 1 | 3 | | 2005 | 1 | 1 | 2 | | 2006 | 1 | 0 | 1 | | 2007 | 3 | 2 | 5 | | 2008 | 1 | 0 | 1 | | 2009 | 3 | 0 | 3 | | 2012 | 1 | 0 | 1 | | 2015 | 0 | 2 | 2 | | 2017 | 2 | 0 | 2 | | 2018 | 0 | 1 | 1 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "RNA, Catalytic" by people in Profiles.
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Wolk SK, Mayfield WS, Gelinas AD, Astling D, Guillot J, Brody EN, Janjic N, Gold L. Modified nucleotides may have enhanced early RNA catalysis. Proc Natl Acad Sci U S A. 2020 04 14; 117(15):8236-8242.
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Shoffner GM, Wang R, Podell E, Cech TR, Guo F. In Crystallo Selection to Establish New RNA Crystal Contacts. Structure. 2018 09 04; 26(9):1275-1283.e3.
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Miao Z, Adamiak RW, Antczak M, Batey RT, Becka AJ, Biesiada M, Boniecki MJ, Bujnicki JM, Chen SJ, Cheng CY, Chou FC, Ferré-D'Amaré AR, Das R, Dawson WK, Ding F, Dokholyan NV, Dunin-Horkawicz S, Geniesse C, Kappel K, Kladwang W, Krokhotin A, Lach GE, Major F, Mann TH, Magnus M, Pachulska-Wieczorek K, Patel DJ, Piccirilli JA, Popenda M, Purzycka KJ, Ren A, Rice GM, Santalucia J, Sarzynska J, Szachniuk M, Tandon A, Trausch JJ, Tian S, Wang J, Weeks KM, Williams B, Xiao Y, Xu X, Zhang D, Zok T, Westhof E. RNA-Puzzles Round III: 3D RNA structure prediction of five riboswitches and one ribozyme. RNA. 2017 05; 23(5):655-672.
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Porter EB, Polaski JT, Morck MM, Batey RT. Recurrent RNA motifs as scaffolds for genetically encodable small-molecule biosensors. Nat Chem Biol. 2017 03; 13(3):295-301.
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Goff LA, Rinn JL. Linking RNA biology to lncRNAs. Genome Res. 2015 Oct; 25(10):1456-65.
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Batey RT. Riboswitches: still a lot of undiscovered country. RNA. 2015 Apr; 21(4):560-3.
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Morrow PK, Murthy RK, Ensor JD, Gordon GS, Margolin KA, Elias AD, Urba WJ, Weng DE, Rugo HS, Hortobagyi GN. An open-label, phase 2 trial of RPI.4610 (Angiozyme) in the treatment of metastatic breast cancer. Cancer. 2012 Sep 01; 118(17):4098-104.
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Drummond PD, Vaughan TG, Drummond AJ. Extinction times in autocatalytic systems. J Phys Chem A. 2010 Oct 07; 114(39):10481-91.
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Fong N, Ohman M, Bentley DL. Fast ribozyme cleavage releases transcripts from RNA polymerase II and aborts co-transcriptional pre-mRNA processing. Nat Struct Mol Biol. 2009 Sep; 16(9):916-22.
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Cech TR. Crawling out of the RNA world. Cell. 2009 Feb 20; 136(4):599-602.
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