 Gene Rearrangement
"Gene Rearrangement" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The ordered rearrangement of gene regions by DNA recombination such as that which occurs normally during development.
| Descriptor ID |
D015321
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| MeSH Number(s) |
G05.344
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| Concept/Terms |
Gene Rearrangement- Gene Rearrangement
- Gene Rearrangements
- Rearrangement, Gene
- Rearrangements, Gene
- DNA Rearrangement
- DNA Rearrangements
- Rearrangement, DNA
- Rearrangements, DNA
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Below are MeSH descriptors whose meaning is more general than "Gene Rearrangement".
Below are MeSH descriptors whose meaning is more specific than "Gene Rearrangement".
This graph shows the total number of publications written about "Gene Rearrangement" by people in this website by year, and whether "Gene Rearrangement" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 0 | 2 | 2 | | 1991 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1998 | 1 | 1 | 2 | | 1999 | 0 | 3 | 3 | | 2000 | 0 | 1 | 1 | | 2002 | 0 | 2 | 2 | | 2004 | 1 | 3 | 4 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 2 | 3 | | 2009 | 2 | 0 | 2 | | 2010 | 1 | 2 | 3 | | 2011 | 2 | 1 | 3 | | 2012 | 1 | 3 | 4 | | 2013 | 3 | 2 | 5 | | 2014 | 1 | 2 | 3 | | 2015 | 6 | 4 | 10 | | 2016 | 3 | 4 | 7 | | 2017 | 4 | 4 | 8 | | 2018 | 4 | 2 | 6 | | 2019 | 0 | 2 | 2 |
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Below are the most recent publications written about "Gene Rearrangement" by people in Profiles.
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Davies KD, Villalobos VM, Aisner DL. Ready or Not, Here I Come: Inflammatory Myofibroblastic Tumors With Kinase Alterations Revealed Through Molecular Hide and Seek. J Thorac Oncol. 2019 05; 14(5):758-760.
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Gu Z, Churchman ML, Roberts KG, Moore I, Zhou X, Nakitandwe J, Hagiwara K, Pelletier S, Gingras S, Berns H, Payne-Turner D, Hill A, Iacobucci I, Shi L, Pounds S, Cheng C, Pei D, Qu C, Newman S, Devidas M, Dai Y, Reshmi SC, Gastier-Foster J, Raetz EA, Borowitz MJ, Wood BL, Carroll WL, Zweidler-McKay PA, Rabin KR, Mattano LA, Maloney KW, Rambaldi A, Spinelli O, Radich JP, Minden MD, Rowe JM, Luger S, Litzow MR, Tallman MS, Racevskis J, Zhang Y, Bhatia R, Kohlschmidt J, Mrózek K, Bloomfield CD, Stock W, Kornblau S, Kantarjian HM, Konopleva M, Evans WE, Jeha S, Pui CH, Yang J, Paietta E, Downing JR, Relling MV, Zhang J, Loh ML, Hunger SP, Mullighan CG. PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia. Nat Genet. 2019 02; 51(2):296-307.
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Solomon BJ, Besse B, Bauer TM, Felip E, Soo RA, Camidge DR, Chiari R, Bearz A, Lin CC, Gadgeel SM, Riely GJ, Tan EH, Seto T, James LP, Clancy JS, Abbattista A, Martini JF, Chen J, Peltz G, Thurm H, Ou SI, Shaw AT. Lorlatinib in patients with ALK-positive non-small-cell lung cancer: results from a global phase 2 study. Lancet Oncol. 2018 12; 19(12):1654-1667.
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Chen Y, Jones KL, Anastassiadis K, Kranz A, Stewart AF, Grembecka J, Meyerson M, Ernst P. Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemia. Exp Hematol. 2019 01; 69:37-42.
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Patil T, Smith DE, Bunn PA, Aisner DL, Le AT, Hancock M, Purcell WT, Bowles DW, Camidge DR, Doebele RC. The Incidence of Brain Metastases in Stage IV ROS1-Rearranged Non-Small Cell Lung Cancer and Rate of Central Nervous System Progression on Crizotinib. J Thorac Oncol. 2018 11; 13(11):1717-1726.
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Rudzinski ER, Lockwood CM, Stohr BA, Vargas SO, Sheridan R, Black JO, Rajaram V, Laetsch TW, Davis JL. Pan-Trk Immunohistochemistry Identifies NTRK Rearrangements in Pediatric Mesenchymal Tumors. Am J Surg Pathol. 2018 07; 42(7):927-935.
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Villalobos VM, Camidge DR. Targeting ALK in inflammatory myofibroblastic tumours. Lancet Respir Med. 2018 06; 6(6):405-407.
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Balla A, Khan F, Hampel KJ, Aisner DL, Sidiropoulos N. Small-cell transformation of ALK-rearranged non-small-cell adenocarcinoma of the lung. Cold Spring Harb Mol Case Stud. 2018 04; 4(2).
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Greer RO, Eskendri J, Freedman P, Ahmadian M, Murakami-Walter A, Varella-Garcia M. Assessment of biologically aggressive, recurrent glandular odontogenic cysts for mastermind-like 2 (MAML2) rearrangements: histopathologic and fluorescent in situ hybridization (FISH) findings in 11 cases. J Oral Pathol Med. 2018 Feb; 47(2):192-197.
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Wierda WG, Byrd JC, Abramson JS, Bhat S, Bociek G, Brander D, Brown J, Chanan-Khan A, Coutre SE, Davis RS, Fletcher CD, Hill B, Kahl BS, Kamdar M, Kaplan LD, Khan N, Kipps TJ, Lancet J, Ma S, Malek S, Mosse C, Shadman M, Siddiqi T, Stephens D, Wagner N, Zelenetz AD, Dwyer MA, Sundar H. Hairy Cell Leukemia, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2017 11; 15(11):1414-1427.
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