 Nitric Oxide
"Nitric Oxide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
| Descriptor ID |
D009569
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| MeSH Number(s) |
D01.339.387 D01.625.550.500 D01.625.700.500 D01.650.550.587.600
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| Concept/Terms |
Nitric Oxide- Nitric Oxide
- Oxide, Nitric
- Mononitrogen Monoxide
- Monoxide, Mononitrogen
- Nitrogen Monoxide
- Monoxide, Nitrogen
- Endogenous Nitrate Vasodilator
- Nitrate Vasodilator, Endogenous
- Vasodilator, Endogenous Nitrate
- Nitric Oxide, Endothelium-Derived
- Endothelium-Derived Nitric Oxide
- Nitric Oxide, Endothelium Derived
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Below are MeSH descriptors whose meaning is more general than "Nitric Oxide".
Below are MeSH descriptors whose meaning is more specific than "Nitric Oxide".
This graph shows the total number of publications written about "Nitric Oxide" by people in this website by year, and whether "Nitric Oxide" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1989 | 1 | 0 | 1 | | 1990 | 1 | 0 | 1 | | 1991 | 1 | 0 | 1 | | 1992 | 3 | 0 | 3 | | 1993 | 8 | 2 | 10 | | 1994 | 12 | 2 | 14 | | 1995 | 15 | 5 | 20 | | 1996 | 14 | 1 | 15 | | 1997 | 22 | 8 | 30 | | 1998 | 15 | 6 | 21 | | 1999 | 14 | 8 | 22 | | 2000 | 11 | 2 | 13 | | 2001 | 8 | 6 | 14 | | 2002 | 10 | 15 | 25 | | 2003 | 10 | 6 | 16 | | 2004 | 11 | 10 | 21 | | 2005 | 13 | 18 | 31 | | 2006 | 9 | 9 | 18 | | 2007 | 10 | 15 | 25 | | 2008 | 21 | 16 | 37 | | 2009 | 6 | 18 | 24 | | 2010 | 8 | 12 | 20 | | 2011 | 11 | 13 | 24 | | 2012 | 12 | 19 | 31 | | 2013 | 12 | 14 | 26 | | 2014 | 14 | 13 | 27 | | 2015 | 9 | 10 | 19 | | 2016 | 9 | 15 | 24 | | 2017 | 2 | 7 | 9 |
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Below are the most recent publications written about "Nitric Oxide" by people in Profiles.
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Klawitter J, Hildreth KL, Christians U, Kohrt WM, Moreau KL. A relative L-arginine deficiency contributes to endothelial dysfunction across the stages of the menopausal transition. Physiol Rep. 2017 Sep; 5(17).
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Xu W, Comhair SAA, Janocha AJ, Lara A, Mavrakis LA, Bennett CD, Kalhan SC, Erzurum SC. Arginine metabolic endotypes related to asthma severity. PLoS One. 2017; 12(8):e0183066.
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Anenberg SC, Miller J, Minjares R, Du L, Henze DK, Lacey F, Malley CS, Emberson L, Franco V, Klimont Z, Heyes C. Impacts and mitigation of excess diesel-related NOx emissions in 11 major vehicle markets. Nature. 2017 05 25; 545(7655):467-471.
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Lanz MJ, Gonzalez MM, Efaw BJ, Harbeck RJ. Higher fractional exhaled nitric oxide and Der p 1 exposure in children with asthma living in tropical environments. Ann Allergy Asthma Immunol. 2017 06; 118(6):731-732.
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Green JB, Hart B, Cornett EM, Kaye AD, Salehi A, Fox CJ. Pulmonary Vasodilators and Anesthesia Considerations. Anesthesiol Clin. 2017 Jun; 35(2):221-232.
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Dos Santos JC, Heinhuis B, Gomes RS, Damen MS, Real F, Mortara RA, Keating ST, Dinarello CA, Joosten LA, Ribeiro-Dias F. Cytokines and microbicidal molecules regulated by IL-32 in THP-1-derived human macrophages infected with New World Leishmania species. PLoS Negl Trop Dis. 2017 Feb; 11(2):e0005413.
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Denlinger LC, Phillips BR, Ramratnam S, Ross K, Bhakta NR, Cardet JC, Castro M, Peters SP, Phipatanakul W, Aujla S, Bacharier LB, Bleecker ER, Comhair SA, Coverstone A, DeBoer M, Erzurum SC, Fain SB, Fajt M, Fitzpatrick AM, Gaffin J, Gaston B, Hastie AT, Hawkins GA, Holguin F, Irani AM, Israel E, Levy BD, Ly N, Meyers DA, Moore WC, Myers R, Opina MT, Peters MC, Schiebler ML, Sorkness RL, Teague WG, Wenzel SE, Woodruff PG, Mauger DT, Fahy JV, Jarjour NN. Inflammatory and Comorbid Features of Patients with Severe Asthma and Frequent Exacerbations. Am J Respir Crit Care Med. 2017 Feb 01; 195(3):302-313.
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Farabaugh KT, Majumder M, Guan BJ, Jobava R, Wu J, Krokowski D, Gao XH, Schuster A, Longworth M, Chan ED, Bianchi M, Dey M, Koromilas AE, Ramakrishnan P, Hatzoglou M. Protein Kinase R Mediates the Inflammatory Response Induced by Hyperosmotic Stress. Mol Cell Biol. 2017 Feb 15; 37(4).
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Chen YC, Liou TH, Chen PC, Chiang BL, Yang YH, Fan HY, Lee YL. Growth trajectories and asthma/rhinitis in children: a longitudinal study in Taiwan. Eur Respir J. 2017 Jan; 49(1).
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Akolkar G, Bagchi AK, Ayyappan P, Jassal DS, Singal PK. Doxorubicin-induced nitrosative stress is mitigated by vitamin C via the modulation of nitric oxide synthases. Am J Physiol Cell Physiol. 2017 Apr 01; 312(4):C418-C427.
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