 Nitric Oxide
"Nitric Oxide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
| Descriptor ID |
D009569
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| MeSH Number(s) |
D01.339.387 D01.625.550.500 D01.625.700.500 D01.650.550.587.600
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| Concept/Terms |
Nitric Oxide- Nitric Oxide
- Oxide, Nitric
- Nitrogen Monoxide
- Monoxide, Nitrogen
- Nitric Oxide, Endothelium-Derived
- Endothelium-Derived Nitric Oxide
- Nitric Oxide, Endothelium Derived
- Endogenous Nitrate Vasodilator
- Nitrate Vasodilator, Endogenous
- Vasodilator, Endogenous Nitrate
- Mononitrogen Monoxide
- Monoxide, Mononitrogen
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Below are MeSH descriptors whose meaning is more general than "Nitric Oxide".
Below are MeSH descriptors whose meaning is more specific than "Nitric Oxide".
This graph shows the total number of publications written about "Nitric Oxide" by people in this website by year, and whether "Nitric Oxide" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 3 | 2 | 5 | | 1994 | 5 | 1 | 6 | | 1995 | 9 | 3 | 12 | | 1996 | 11 | 0 | 11 | | 1997 | 15 | 6 | 21 | | 1998 | 7 | 3 | 10 | | 1999 | 12 | 6 | 18 | | 2000 | 6 | 2 | 8 | | 2001 | 6 | 5 | 11 | | 2002 | 3 | 9 | 12 | | 2003 | 5 | 4 | 9 | | 2004 | 9 | 5 | 14 | | 2005 | 11 | 12 | 23 | | 2006 | 5 | 3 | 8 | | 2007 | 8 | 12 | 20 | | 2008 | 11 | 12 | 23 | | 2009 | 6 | 12 | 18 | | 2010 | 8 | 9 | 17 | | 2011 | 10 | 6 | 16 | | 2012 | 9 | 7 | 16 | | 2013 | 8 | 5 | 13 | | 2014 | 7 | 12 | 19 | | 2015 | 8 | 6 | 14 | | 2016 | 8 | 8 | 16 | | 2017 | 3 | 5 | 8 | | 2018 | 2 | 5 | 7 | | 2019 | 6 | 9 | 15 | | 2020 | 7 | 6 | 13 | | 2021 | 6 | 4 | 10 | | 2022 | 1 | 4 | 5 |
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Below are the most recent publications written about "Nitric Oxide" by people in Profiles.
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Shannon OM, Clifford T, Seals DR, Craighead DH, Rossman MJ. Nitric oxide, aging and aerobic exercise: Sedentary individuals to Master's athletes. Nitric Oxide. 2022 08 01; 125-126:31-39.
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Strickland B, Albala L, Coffey EC, Carroll RW, Zapol WM, Ichinose F, Berra L, Harris NS. Safety and practicality of high dose inhaled nitric oxide in emergency department COVID-19 patients. Am J Emerg Med. 2022 08; 58:5-8.
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Venturelli M, Rossman MJ, Ives SJ, Weavil JC, Amann M, Wray DW, Richardson RS. Passive leg movement-induced vasodilation and exercise-induced sympathetic vasoconstriction. Auton Neurosci. 2022 05; 239:102969.
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Yates AR, Berger JT, Reeder RW, Banks R, Mourani PM, Berg RA, Carcillo JA, Carpenter T, Hall MW, Meert KL, McQuillen PS, Pollack MM, Sapru A, Notterman DA, Holubkov R, Dean JM, Wessel DL. Characterization of Inhaled Nitric Oxide Use for Cardiac Indications in Pediatric Patients. Pediatr Crit Care Med. 2022 04 01; 23(4):245-254.
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Singh V, Akash R, Chaudhary G, Singh R, Choudhury S, Shukla A, Prabhu SN, Gangwar N, Garg SK. Sepsis downregulates aortic Notch signaling to produce vascular hyporeactivity in mice. Sci Rep. 2022 02 21; 12(1):2941.
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Snyder JP, Gullickson SK, Del Rio-Guerra R, Sweezy A, Vagher B, Hogan TC, Lahue KG, Reisz JA, D'Alessandro A, Krementsov DN, Amiel E. Divergent Genetic Regulation of Nitric Oxide Production between C57BL/6J and Wild-Derived PWD/PhJ Mice Controls Postactivation Mitochondrial Metabolism, Cell Survival, and Bacterial Resistance in Dendritic Cells. J Immunol. 2022 01 01; 208(1):97-109.
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Nelin L, Kinsella JP, Courtney SE, Pallotto EK, Tarau E, Potenziano JL. Use of inhaled nitric oxide in preterm vs term/near-term neonates with pulmonary hypertension: results of the PaTTerN registry study. J Perinatol. 2022 01; 42(1):14-18.
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Maddux AB, Mourani PM, Banks R, Reeder RW, Pollack MM, Berg RA, Meert KL, McQuillen PS, Yates AR, Notterman DA, Berger JT. Inhaled Nitric Oxide Use and Outcomes in Critically Ill Children With a History of Prematurity. Respir Care. 2021 Oct; 66(10):1549-1559.
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Mudan A, Lebin JA. Response to "The Mechanisms Underlying Methylene Blue-Mediated Attenuation of Nitric Oxide-induced Vasodilatation". J Emerg Med. 2021 05; 60(5):680.
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Schäfer M, Frank BS, Ivy DD, Abman SH, Stenmark KR, Mitchell MB, Browne LP, Barker AJ, Hunter KS, Kheyfets V, Miller-Reed K, Ing R, Morgan GJ, Truong U. Short-Term Effects of Inhaled Nitric Oxide on Right Ventricular Flow Hemodynamics by 4-Dimensional-Flow Magnetic Resonance Imaging in Children With Pulmonary Arterial Hypertension. J Am Heart Assoc. 2021 04 20; 10(8):e020548.
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