 Nitric Oxide
"Nitric Oxide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
| Descriptor ID |
D009569
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| MeSH Number(s) |
D01.339.387 D01.625.550.500 D01.625.700.500 D01.650.550.587.600
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| Concept/Terms |
Nitric Oxide- Nitric Oxide
- Oxide, Nitric
- Nitrogen Monoxide
- Monoxide, Nitrogen
- Nitric Oxide, Endothelium-Derived
- Endothelium-Derived Nitric Oxide
- Nitric Oxide, Endothelium Derived
- Endogenous Nitrate Vasodilator
- Nitrate Vasodilator, Endogenous
- Vasodilator, Endogenous Nitrate
- Mononitrogen Monoxide
- Monoxide, Mononitrogen
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Below are MeSH descriptors whose meaning is more general than "Nitric Oxide".
Below are MeSH descriptors whose meaning is more specific than "Nitric Oxide".
This graph shows the total number of publications written about "Nitric Oxide" by people in this website by year, and whether "Nitric Oxide" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 1 | 0 | 1 | | 1992 | 2 | 0 | 2 | | 1993 | 6 | 1 | 7 | | 1994 | 12 | 2 | 14 | | 1995 | 16 | 5 | 21 | | 1996 | 14 | 1 | 15 | | 1997 | 22 | 8 | 30 | | 1998 | 14 | 5 | 19 | | 1999 | 17 | 8 | 25 | | 2000 | 10 | 2 | 12 | | 2001 | 5 | 7 | 12 | | 2002 | 7 | 14 | 21 | | 2003 | 11 | 6 | 17 | | 2004 | 12 | 9 | 21 | | 2005 | 13 | 18 | 31 | | 2006 | 10 | 8 | 18 | | 2007 | 10 | 13 | 23 | | 2008 | 19 | 15 | 34 | | 2009 | 7 | 14 | 21 | | 2010 | 8 | 12 | 20 | | 2011 | 13 | 11 | 24 | | 2012 | 12 | 12 | 24 | | 2013 | 9 | 11 | 20 | | 2014 | 11 | 13 | 24 | | 2015 | 12 | 10 | 22 | | 2016 | 8 | 9 | 17 | | 2017 | 4 | 6 | 10 | | 2018 | 3 | 9 | 12 | | 2019 | 7 | 15 | 22 | | 2020 | 6 | 3 | 9 |
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Below are the most recent publications written about "Nitric Oxide" by people in Profiles.
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Wang K, Verbakel JY, Oke J, Fleming-Nouri A, Harada N, Atsuta R, Fujisawa T, Kawayama T, Inoue H, Lazarus S, Szefler S, Martinez FD, Shaw D, Pavord ID, Thomas M. Using fractional exhaled nitric oxide to guide step-down treatment decisions in asthma: practical considerations. Eur Respir J. 2020 08; 56(2).
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Berger JT, Maddux AB, Reeder RW, Banks R, Mourani PM, Berg RA, Carcillo JA, Carpenter T, Hall MW, Meert KL, McQuillen PS, Pollack MM, Sapru A, Yates AR, Notterman DA, Holubkov R, Dean JM, Wessel DL. Inhaled Nitric Oxide Use in Pediatric Hypoxemic Respiratory Failure. Pediatr Crit Care Med. 2020 08; 21(8):708-719.
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Lorca RA, Matarazzo CJ, Bales ES, Houck JA, Orlicky DJ, Euser AG, Julian CG, Moore LG. AMPK activation in pregnant human myometrial arteries from high-altitude and intrauterine growth-restricted pregnancies. Am J Physiol Heart Circ Physiol. 2020 07 01; 319(1):H203-H212.
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Wang K, Verbakel JY, Oke J, Fleming-Nouri A, Brewin J, Roberts N, Harada N, Atsuta R, Takahashi K, Mori K, Fujisawa T, Shirai T, Kawayama T, Inoue H, Lazarus S, Szefler S, Martinez F, Shaw D, Pavord ID, Thomas M. Using fractional exhaled nitric oxide to guide step-down treatment decisions in patients with asthma: a systematic review and individual patient data meta-analysis. Eur Respir J. 2020 05; 55(5).
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Fielding SS, Pijnenburg M, de Jongste J, Pike K, Roberts G, Petsky H, Chang AB, Fritsch M, Frischer T, Szefler SJ, Gergen P, Vermeulen F, Vael R, Turner SS. Does treatment guided by exhaled nitric oxide fraction improve outcomes in subgroups of children with asthma? Eur Respir J. 2020 05; 55(5).
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Brewster LM, Coombs GB, Garcia VP, Hijmans JG, DeSouza NM, Stockelman KA, Barak OF, Mijacika T, Dujic Z, Greiner JJ, Phillips AA, Ainslie PN, DeSouza CA. Effects of circulating extracellular microvesicles from spinal cord-injured adults on endothelial cell function. Clin Sci (Lond). 2020 04 17; 134(7):777-789.
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Gien J, Nuxoll C, Kinsella JP. Inhaled Nitric Oxide in Emergency Medical Transport of the Newborn. Neoreviews. 2020 03; 21(3):e157-e164.
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Jones-Carson J, Yahashiri A, Kim JS, Liu L, Fitzsimmons LF, Weiss DS, Vázquez-Torres A. Nitric oxide disrupts bacterial cytokinesis by poisoning purine metabolism. Sci Adv. 2020 02; 6(9):eaaz0260.
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Fielding S, Pijnenburg M, de Jongste J, Pike K, Roberts G, Petsky H, Chang AB, Fritsch M, Frischer T, Szefler S, Gergen P, Vermeulen F, Vael R, Turner S. What is a clinically meaningful change in exhaled nitric oxide for children with asthma? Pediatr Pulmonol. 2020 03; 55(3):599-606.
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Holguin F, Grasemann H, Sharma S, Winnica D, Wasil K, Smith V, Cruse MH, Perez N, Coleman E, Scialla TJ, Que LG. L-Citrulline increases nitric oxide and improves control in obese asthmatics. JCI Insight. 2019 12 19; 4(24).
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