 Nitric Oxide
"Nitric Oxide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
| Descriptor ID |
D009569
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| MeSH Number(s) |
D01.339.387 D01.625.550.500 D01.625.700.500 D01.650.550.587.600
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| Concept/Terms |
Nitric Oxide- Nitric Oxide
- Oxide, Nitric
- Nitrogen Monoxide
- Monoxide, Nitrogen
- Nitric Oxide, Endothelium-Derived
- Endothelium-Derived Nitric Oxide
- Nitric Oxide, Endothelium Derived
- Endogenous Nitrate Vasodilator
- Nitrate Vasodilator, Endogenous
- Vasodilator, Endogenous Nitrate
- Mononitrogen Monoxide
- Monoxide, Mononitrogen
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Below are MeSH descriptors whose meaning is more general than "Nitric Oxide".
Below are MeSH descriptors whose meaning is more specific than "Nitric Oxide".
This graph shows the total number of publications written about "Nitric Oxide" by people in this website by year, and whether "Nitric Oxide" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 1 | 0 | 1 | | 1991 | 1 | 0 | 1 | | 1992 | 2 | 0 | 2 | | 1993 | 6 | 1 | 7 | | 1994 | 12 | 2 | 14 | | 1995 | 15 | 5 | 20 | | 1996 | 14 | 1 | 15 | | 1997 | 21 | 8 | 29 | | 1998 | 14 | 5 | 19 | | 1999 | 15 | 8 | 23 | | 2000 | 10 | 2 | 12 | | 2001 | 5 | 7 | 12 | | 2002 | 11 | 14 | 25 | | 2003 | 12 | 6 | 18 | | 2004 | 12 | 9 | 21 | | 2005 | 13 | 18 | 31 | | 2006 | 10 | 10 | 20 | | 2007 | 10 | 13 | 23 | | 2008 | 20 | 16 | 36 | | 2009 | 7 | 15 | 22 | | 2010 | 9 | 12 | 21 | | 2011 | 13 | 10 | 23 | | 2012 | 12 | 12 | 24 | | 2013 | 9 | 11 | 20 | | 2014 | 11 | 13 | 24 | | 2015 | 12 | 9 | 21 | | 2016 | 8 | 12 | 20 | | 2017 | 5 | 6 | 11 | | 2018 | 3 | 9 | 12 | | 2019 | 3 | 10 | 13 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nitric Oxide" by people in Profiles.
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Brewster LM, Coombs GB, Garcia VP, Hijmans JG, DeSouza NM, Stockelman KA, Barak OF, Mijacika T, Dujic Z, Greiner JJ, Phillips AA, Ainslie PN, DeSouza CA. Effects of circulating extracellular microvesicles from spinal cord-injured adults on endothelial cell function. Clin Sci (Lond). 2020 04 17; 134(7):777-789.
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Guerra DD, Bok R, Vyas V, Orlicky DJ, Lorca RA, Hurt KJ. Akt phosphorylation of neuronal nitric oxide synthase regulates gastrointestinal motility in mouse ileum. Proc Natl Acad Sci U S A. 2019 08 27; 116(35):17541-17546.
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Brothers RM, Fadel PJ, Keller DM. Racial disparities in cardiovascular disease risk: mechanisms of vascular dysfunction. Am J Physiol Heart Circ Physiol. 2019 10 01; 317(4):H777-H789.
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Beghetti M, Gorenflo M, Ivy DD, Moledina S, Bonnet D. Treatment of pediatric pulmonary arterial hypertension: A focus on the NO-sGC-cGMP pathway. Pediatr Pulmonol. 2019 10; 54(10):1516-1526.
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Johnson Kameny R, Datar SA, Boehme JB, Morris C, Zhu T, Goudy BD, Johnson EG, Galambos C, Raff GW, Sun X, Wang T, Chiacchia SR, Lu Q, Black SM, Maltepe E, Fineman JR. Ovine Models of Congenital Heart Disease and the Consequences of Hemodynamic Alterations for Pulmonary Artery Remodeling. Am J Respir Cell Mol Biol. 2019 05; 60(5):503-514.
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Favazzo LJ, Gill AL, Farnsworth CW, Mooney RA, Gill SR. The Response of nor and nos Contributes to Staphylococcus aureus Virulence and Metabolism. J Bacteriol. 2019 05 01; 201(9).
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Rogers SC, Moynihan FT, McDonough R, Timm DD, Hovmand-Warner E, Frazier E, Thomas KA, Spinella PC, Doctor A. Effect of plasma processing and storage on microparticle abundance, nitric oxide scavenging, and vasoactivity. Transfusion. 2019 04; 59(S2):1568-1577.
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Mandell EW, Kratimenos P, Abman SH, Steinhorn RH. Drugs for the Prevention and Treatment of Bronchopulmonary Dysplasia. Clin Perinatol. 2019 06; 46(2):291-310.
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Frank BS, Schäfer M, Grenolds A, Ivy DD, Abman SH, Darst JR. Acute Vasoreactivity Testing during Cardiac Catheterization of Neonates with Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension. J Pediatr. 2019 05; 208:127-133.
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Fujita M, Somasundaram V, Basudhar D, Cheng RYS, Ridnour LA, Higuchi H, Imadome K, No JH, Bharadwaj G, Wink DA. Role of nitric oxide in pancreatic cancer cells exhibiting the invasive phenotype. Redox Biol. 2019 04; 22:101158.
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