Genes, MHC Class II
"Genes, MHC Class II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genetic loci in the vertebrate major histocompatibility complex that encode polymorphic products which control the immune response to specific antigens. The genes are found in the HLA-D region in humans and includes H-2M, I-A, and I-E loci in mice.
Descriptor ID |
D005802
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MeSH Number(s) |
G05.360.340.024.340.610.600 G05.360.340.024.380.500.600 G12.500.500.600
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Concept/Terms |
Genes, MHC Class II- Genes, MHC Class II
- Genes, Class II
- MHC Class II Genes
- Class II Genes
- Class II Gene
- Gene, Class II
- Genes, HLA Class II
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Below are MeSH descriptors whose meaning is more general than "Genes, MHC Class II".
Below are MeSH descriptors whose meaning is more specific than "Genes, MHC Class II".
This graph shows the total number of publications written about "Genes, MHC Class II" by people in this website by year, and whether "Genes, MHC Class II" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 | 1999 | 1 | 0 | 1 | 2002 | 1 | 0 | 1 | 2004 | 0 | 2 | 2 | 2005 | 1 | 0 | 1 | 2006 | 2 | 0 | 2 | 2007 | 0 | 1 | 1 | 2008 | 1 | 1 | 2 | 2010 | 1 | 1 | 2 | 2011 | 1 | 0 | 1 | 2012 | 1 | 0 | 1 | 2013 | 1 | 1 | 2 | 2014 | 1 | 2 | 3 | 2015 | 2 | 0 | 2 | 2017 | 2 | 0 | 2 | 2018 | 1 | 0 | 1 | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Genes, MHC Class II" by people in Profiles.
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Jin Y, Roberts GHL, Ferrara TM, Ben S, van Geel N, Wolkerstorfer A, Ezzedine K, Siebert J, Neff CP, Palmer BE, Santorico SA, Spritz RA. Early-onset autoimmune vitiligo associated with an enhancer variant haplotype that upregulates class II HLA expression. Nat Commun. 2019 01 23; 10(1):391.
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Vijayababu P, Samykannu G, Antonyraj CB, Narayanan S, Basheer Ahamed SI, Perumal P, Piramanayagam S. B-cell and T-cell epitope identification with stability analysis of AI-2 import ATP-binding cassette LsrA from S. typhiIn silico approach. Microb Pathog. 2018 Oct; 123:487-495.
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Wang W, Ollila HM, Whittemore AS, Demehri S, Ioannidis NM, Jorgenson E, Mignot E, Asgari MM. Genetic variants in the HLA class II region associated with risk of cutaneous squamous cell carcinoma. Cancer Immunol Immunother. 2018 Jul; 67(7):1123-1133.
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Chatterjee P, Chiasson VL, Seerangan G, De Guzman E, Milad M, Bounds KR, Gasheva O, Tobin RP, Hatahet M, Kopriva S, Jones KA, Newell-Rogers MK, Mitchell BM. Depletion of MHC class II invariant chain peptide or ?-d T-cells ameliorates experimental preeclampsia. Clin Sci (Lond). 2017 08 01; 131(15):2047-2058.
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Norman PJ, Norberg SJ, Guethlein LA, Nemat-Gorgani N, Royce T, Wroblewski EE, Dunn T, Mann T, Alicata C, Hollenbach JA, Chang W, Shults Won M, Gunderson KL, Abi-Rached L, Ronaghi M, Parham P. Sequences of 95 human MHC haplotypes reveal extreme coding variation in genes other than highly polymorphic HLA class I and II. Genome Res. 2017 05; 27(5):813-823.
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Norman PJ, Norberg SJ, Nemat-Gorgani N, Royce T, Hollenbach JA, Shults Won M, Guethlein LA, Gunderson KL, Ronaghi M, Parham P. Very long haplotype tracts characterized at high resolution from HLA homozygous cell lines. Immunogenetics. 2015 Sep; 67(9):479-85.
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Carmona FD, Mackie SL, Mart?n JE, Taylor JC, Vaglio A, Eyre S, Bossini-Castillo L, Casta?eda S, Cid MC, Hern?ndez-Rodr?guez J, Prieto-Gonz?lez S, Solans R, Ramentol-Sintas M, Gonz?lez-Escribano MF, Ortiz-Fern?ndez L, Morado IC, Narv?ez J, Miranda-Filloy JA, Beretta L, Lunardi C, Cimmino MA, Gianfreda D, Santilli D, Ramirez GA, Soriano A, Muratore F, Pazzola G, Addimanda O, Wijmenga C, Witte T, Schirmer JH, Moosig F, Sch?nau V, Franke A, Palm ?, Molberg ?, Diamantopoulos AP, Carette S, Cuthbertson D, Forbess LJ, Hoffman GS, Khalidi NA, Koening CL, Langford CA, McAlear CA, Moreland L, Monach PA, Pagnoux C, Seo P, Spiera R, Sreih AG, Warrington KJ, Ytterberg SR, Gregersen PK, Pease CT, Gough A, Green M, Hordon L, Jarrett S, Watts R, Levy S, Patel Y, Kamath S, Dasgupta B, Worthington J, Koeleman BP, de Bakker PI, Barrett JH, Salvarani C, Merkel PA, Gonz?lez-Gay MA, Morgan AW, Mart?n J. A large-scale genetic analysis reveals a strong contribution of the HLA class II region to giant cell arteritis susceptibility. Am J Hum Genet. 2015 Apr 02; 96(4):565-80.
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Tobin RP, Mukherjee S, Kain JM, Rogers SK, Henderson SK, Motal HL, Newell Rogers MK, Shapiro LA. Traumatic brain injury causes selective, CD74-dependent peripheral lymphocyte activation that exacerbates neurodegeneration. Acta Neuropathol Commun. 2014 Oct 20; 2:143.
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David A, Crawford F, Garside P, Kappler JW, Marrack P, MacLeod M. Tolerance induction in memory CD4 T cells requires two rounds of antigen-specific activation. Proc Natl Acad Sci U S A. 2014 May 27; 111(21):7735-40.
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Schnabel LV, Pezzanite LM, Antczak DF, Felippe MJ, Fortier LA. Equine bone marrow-derived mesenchymal stromal cells are heterogeneous in MHC class II expression and capable of inciting an immune response in vitro. Stem Cell Res Ther. 2014 Jan 24; 5(1):13.
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