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Christene Huang

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-SRG

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Wang Z, Louras NJ, Lellouch AG, Pratts SG, Zhang H, Wang H, Huang CA, Cetrulo CL, Madsen JC, Sachs DH, Wang Z. Dosing optimization of CCR4 immunotoxin for improved depletion of CCR4+ Treg in nonhuman primates. Mol Oncol. 2018 Aug; 12(8):1374-1382. PMID: 29873181.
      View in: PubMed
    2. Navarro-Alvarez N, Gonçalves BMM, Andrews AR, Sachs DH, Huang CA. A CFA-Induced Model of Inflammatory Skin Disease in Miniature Swine. Int J Inflam. 2018; 2018:6916920. PMID: 30034774.
      View in: PubMed
    3. Navarro-Alvarez N, Goncalves B, Andrews AR, Wang Z, Wang Z, Harrington E, Shah J, Sachs DH, Eliaz I, Huang CA. The effects of galectin-3 depletion apheresis on induced skin inflammation in a porcine model. J Clin Apher. 2018 Aug; 33(4):486-493. PMID: 29572917.
      View in: PubMed
    4. Li Z, Navarro-Alvarez N, Keeley EJ, Nowell NH, Goncalves BMM, Huang CA, Evans CL. Non-invasive monitoring of skin inflammation using an oxygen-sensing paint-on bandage. Biomed Opt Express. 2017 Oct 01; 8(10):4640-4651. PMID: 29082091.
      View in: PubMed
    5. Wang Z, Zheng Q, Zhang H, Bronson RT, Madsen JC, Sachs DH, Huang CA, Wang Z. Ontak-like human IL-2 fusion toxin. J Immunol Methods. 2017 09; 448:51-58. PMID: 28551309.
      View in: PubMed
    6. Zheng Q, Wang Z, Zhang H, Huang Q, Madsen JC, Sachs DH, Huang CA, Wang Z. Diphtheria toxin-based anti-human CD19 immunotoxin for targeting human CD19+ tumors. Mol Oncol. 2017 05; 11(5):584-594. PMID: 28306193.
      View in: PubMed
    7. Eliaz I, Patil A, Navarro-Alvarez N, Wang Z, Eliaz A, Weil E, Wilk B, Sachs DH, Huang CA. Methods for the detection and serum depletion of porcine galectin-3. J Clin Apher. 2017 Oct; 32(5):335-341. PMID: 28083958.
      View in: PubMed
    8. Wang Z, Navarro-Alvarez N, Shah JA, Zhang H, Huang Q, Zheng Q, Madsen JC, Sachs DH, Huang CA, Wang Z. Porcine Treg depletion with a novel diphtheria toxin-based anti-human CCR4 immunotoxin. Vet Immunol Immunopathol. 2016 Dec; 182:150-158. PMID: 27863545.
      View in: PubMed
    9. Climov M, Matar AJ, Farkash EA, Medeiros E, Qiao J, Harrington E, Gusha A, Al-Musa A, Sachs DH, Randolph M, Bollenbach TJ, Huang CA. Survival of Allogeneic Self-Assembled Cultured Skin. Transplantation. 2016 10; 100(10):2071-8. PMID: 27479166.
      View in: PubMed
    10. Duran-Struuck R, Matar AJ, Crepeau RL, Teague AGS, Horner BM, Pathiraja V, Spitzer TR, Fishman JA, Bronson RT, Sachs DH, Huang CA. Donor Lymphocyte Infusion-Mediated Graft-versus-Host Responses in a Preclinical Swine Model of Haploidentical Hematopoietic Cell Transplantation. Biol Blood Marrow Transplant. 2016 11; 22(11):1953-1960. PMID: 27543159.
      View in: PubMed
    11. Climov M, Medeiros E, Farkash EA, Qiao J, Rousseau CF, Dong S, Zawadzka A, Racki WJ, Al-Musa A, Sachs DH, Randolph MA, Huang CA, Bollenbach TJ. Bioengineered Self-assembled Skin as an Alternative to Skin Grafts. Plast Reconstr Surg Glob Open. 2016 Jun; 4(6):e731. PMID: 27482479; PMCID: PMC4956843.
    12. Duran-Struuck R, Matar AJ, Huang CA. Myeloid Leukemias and Virally Induced Lymphomas in Miniature Inbred Swine: Development of a Large Animal Tumor Model. Front Genet. 2015; 6:332. PMID: 26635868; PMCID: PMC4653297.
    13. Wang Z, Pratts SG, Zhang H, Spencer PJ, Yu R, Tonsho M, Shah JA, Tanabe T, Powell HR, Huang CA, Madsen JC, Sachs DH, Wang Z. Treg depletion in non-human primates using a novel diphtheria toxin-based anti-human CCR4 immunotoxin. Mol Oncol. 2016 Apr; 10(4):553-65. PMID: 26643572; PMCID: PMC4826841 [Available on 04/01/17].
    14. Duran-Struuck R, Huang CA, Orf K, Bronson RT, Sachs DH, Spitzer TR. Miniature Swine as a Clinically Relevant Model of Graft-Versus-Host Disease. Comp Med. 2015 Oct; 65(5):429-43. PMID: 26473348; PMCID: PMC4617335.
    15. Navarro Alvarez N, Zhu A, Arellano RS, Randolph MA, Duggan M, Scott Arn J, Huang CA, Sachs DH, Vagefi PA. Postnatal xenogeneic B-cell tolerance in swine following in utero intraportal antigen exposure. Xenotransplantation. 2015 Sep-Oct; 22(5):368-78. PMID: 26314946.
      View in: PubMed
    16. Matar AJ, Patil AR, Al-Musa A, Hanekamp I, Sachs DH, Huang CA, Duran-Struuck R. Effect of Irradiation on Incidence of Post-Transplant Lymphoproliferative Disorder after Hematopoietic Cell Transplantation in Miniature Swine. Biol Blood Marrow Transplant. 2015 Oct; 21(10):1732-8. PMID: 26210443.
      View in: PubMed
    17. Madariaga ML, Michel SG, La Muraglia GM, Sihag S, Leonard DA, Farkash EA, Colvin RB, Cetrulo CL, Huang CA, Sachs DH, Madsen JC, Allan JS. Recipient-matching of Passenger Leukocytes Prolongs Survival of Donor Lung Allografts in Miniature Swine. Transplantation. 2015 Jul; 99(7):1372-8. PMID: 25757217; PMCID: PMC4494890.
    18. Wang Z, Wei M, Zhang H, Chen H, Germana S, Huang CA, Madsen JC, Sachs DH, Wang Z. Diphtheria-toxin based anti-human CCR4 immunotoxin for targeting human CCR4(+) cells in vivo. Mol Oncol. 2015 Aug; 9(7):1458-70. PMID: 25958791.
      View in: PubMed
    19. Wei M, Marino J, Trowell A, Zhang H, Stromp Peraino J, Rajasekera PV, Madsen JC, Sachs DH, Huang CA, Benichou G, Wang Z. Diphtheria toxin-based recombinant murine IL-2 fusion toxin for depleting murine regulatory T cells in vivo. Protein Eng Des Sel. 2014 Sep; 27(9):289-95. PMID: 25147093.
      View in: PubMed
    20. Mathes DW, Solari MG, Gazelle GS, Butler PE, Wu A, Nazzal A, Nielsen GP, Huang CA, Sachs DH, Lee WP, Randolph MA. Stable mixed hematopoietic chimerism permits tolerance of vascularized composite allografts across a full major histocompatibility mismatch in swine. Transpl Int. 2014 Oct; 27(10):1086-96. PMID: 24963743.
      View in: PubMed
    21. Bharti K, Rao M, Hull SC, Stroncek D, Brooks BP, Feigal E, van Meurs JC, Huang CA, Miller SS. Developing cellular therapies for retinal degenerative diseases. Invest Ophthalmol Vis Sci. 2014 Feb 26; 55(2):1191-202. PMID: 24573369; PMCID: PMC4587754.
    22. Peraino JS, Zhang H, Rajasekera PV, Wei M, Madsen JC, Sachs DH, Huang CA, Wang Z. Diphtheria toxin-based bivalent human IL-2 fusion toxin with improved efficacy for targeting human CD25(+) cells. J Immunol Methods. 2014 Mar; 405:57-66. PMID: 24462799; PMCID: PMC4120078.
    23. Liang F, Wamala I, Scalea J, Tena A, Cormack T, Pratts S, Duran-Struuck R, Elias N, Hertl M, Huang CA, Sachs DH. Increased levels of anti-non-Gal IgG following pig-to-baboon bone marrow transplantation correlate with failure of engraftment. Xenotransplantation. 2013 Nov-Dec; 20(6):458-68. PMID: 24289469; PMCID: PMC3848062.
    24. Wamala I, Matar AJ, Farkash E, Wang Z, Huang CA, Sachs DH. Recombinant anti-monkey CD3 immunotoxin depletes peripheral lymph node T lymphocytes more effectively than rabbit anti-thymocyte globulin in naïve baboons. Transpl Immunol. 2013 Dec; 29(1-4):60-3. PMID: 24157659; PMCID: PMC3938119.
    25. Peraino JS, Schenk M, Li G, Zhang H, Farkash EA, Sachs DH, Huang CA, Duran-Struuck R, Wang Z. Development of a diphtheria toxin-based recombinant porcine IL-2 fusion toxin for depleting porcine CD25+ cells. J Immunol Methods. 2013 Dec 15; 398-399:33-43. PMID: 24055128; PMCID: PMC3840057.
    26. Peraino JS, Zhang H, Li G, Huang CA, Wang Z. Molecular basis of cross-species reactivities of human versus porcine CTLA-4. Hum Immunol. 2013 Jul; 74(7):842-8. PMID: 23602875; PMCID: PMC3721328.
    27. Peraino JS, Schenk M, Zhang H, Li G, Hermanrud CE, Neville DM, Sachs DH, Huang CA, Duran-Struuck R, Wang Z. A truncated diphtheria toxin based recombinant porcine CTLA-4 fusion toxin. J Immunol Methods. 2013 May 31; 391(1-2):103-11. PMID: 23470981; PMCID: PMC3688055.
    28. Pathiraja V, Matar AJ, Gusha A, Huang CA, Duran-Struuck R. Leukapheresis protocol for nonhuman primates weighing less than 10 kg. J Am Assoc Lab Anim Sci. 2013 Jan; 52(1):70-7. PMID: 23562036; PMCID: PMC3548204.
    29. Matar AJ, Crepeau RL, Pathiraja V, Robson S, Fishman JA, Spitzer TR, Sachs DH, Huang CA, Duran-Struuck R. Effects of mobilization regimens in donors on outcomes of hematopoietic cell transplantation in miniature Swine. Comp Med. 2012 Dec; 62(6):487-94. PMID: 23561882; PMCID: PMC3527753.
    30. Duran-Struuck R, Matar A, Crepeau R, Gusha A, Schenk M, Hanekamp I, Pathiraja V, Spitzer TR, Sachs DH, Huang CA. Lack of antidonor alloantibody does not indicate lack of immune sensitization: studies of graft loss in a haploidentical hematopoietic cell transplantation swine model. Biol Blood Marrow Transplant. 2012 Nov; 18(11):1629-37. PMID: 22892552.
      View in: PubMed
    31. Crepeau R, Matar A, Spitzer TR, Robson S, Pathiraja V, Sachs DH, Huang CA, Duran-Struuck R. Edema and tetraparesis in a miniature pig after allogeneic hematopoietic cell transplantation. Comp Med. 2012 Aug; 62(4):298-302. PMID: 23043783; PMCID: PMC3415372.
    32. Matar AJ, Pathiraja V, Wang Z, Duran-Struuck R, Gusha A, Crepeau R, Tasaki M, Sachs DH, Huang CA. Effect of pre-existing anti-diphtheria toxin antibodies on T cell depletion levels following diphtheria toxin-based recombinant anti-monkey CD3 immunotoxin treatment. Transpl Immunol. 2012 Aug; 27(1):52-4. PMID: 22676970; PMCID: PMC3413771.
    33. Peraino JS, Hermanrud CE, Springett L, Zhang H, Li G, Srinivasan S, Gusha A, Sachs DH, Huang CA, Wang Z. Expression and characterization of recombinant soluble porcine CD3 ectodomain molecules: mapping the epitope of an anti-porcine CD3 monoclonal antibody 898H2-6-15. Cell Immunol. 2012 Mar-Apr; 276(1-2):162-7. PMID: 22672968; PMCID: PMC3641788.
    34. Peraino J, Zhang H, Hermanrud CE, Li G, Sachs DH, Huang CA, Wang Z. Expression and purification of soluble porcine CTLA-4 in yeast Pichia pastoris. Protein Expr Purif. 2012 Apr; 82(2):270-8. PMID: 22326797; PMCID: PMC3319225.
    35. Hermanrud CE, Pathiraja V, Matar A, Duran-Struuck R, Crepeau RL, Srinivasan S, Sachs DH, Huang CA, Wang Z. Expression and purification of non-N-glycosylated porcine interleukin 3 in yeast Pichia pastoris. Protein Expr Purif. 2012 Mar; 82(1):70-4. PMID: 22154875; PMCID: PMC3288236.
    36. Wang Z, Duran-Struuck R, Crepeau R, Matar A, Hanekamp I, Srinivasan S, Neville DM, Sachs DH, Huang CA. Development of a diphtheria toxin based antiporcine CD3 recombinant immunotoxin. Bioconjug Chem. 2011 Oct 19; 22(10):2014-20. PMID: 21866954; PMCID: PMC3200572.
    37. Hermanrud CE, Lucas CL, Sykes M, Huang CA, Wang Z. Expression and purification of soluble murine CD40L monomers and polymers in yeast Pichia pastoris. Protein Expr Purif. 2011 Mar; 76(1):115-20. PMID: 21074618; PMCID: PMC3005846.
    38. Lutton BV, Cho PS, Hirsh EL, Ferguson KK, Teague AG, Hanekamp JS, Chi N, Goldman SN, Messina DJ, Houser S, Yeap BY, Popma SH, Sachs DH, Huang CA. Approaches to avoid immune responses induced by repeated subcutaneous injections of allogeneic umbilical cord tissue-derived cells. Transplantation. 2010 Sep 15; 90(5):494-501. PMID: 21451445; PMCID: PMC3740357.
    39. Griesemer A, Liang F, Hirakata A, Hirsh E, Lo D, Okumi M, Sykes M, Yamada K, Huang CA, Sachs DH. Occurrence of specific humoral non-responsiveness to swine antigens following administration of GalT-KO bone marrow to baboons. Xenotransplantation. 2010 Jul-Aug; 17(4):300-12. PMID: 20723202; PMCID: PMC2942069.
    40. Duran-Struuck R, Cho PS, Teague AG, Fishman B, Fishman AS, Hanekamp JS, Moran SG, Wikiel KJ, Ferguson KK, Lo DP, Duggan M, Arn JS, Billiter B, Horner B, Houser S, Yeap BY, Westmoreland SV, Spitzer TR, McMorrow IM, Sachs DH, Bronson RT, Huang CA. Myelogenous leukemia in adult inbred MHC-defined miniature swine: a model for human myeloid leukemias. Vet Immunol Immunopathol. 2010 Jun 15; 135(3-4):243-56. PMID: 20079939; PMCID: PMC2879595.
    41. Cho PS, Messina DJ, Hirsh EL, Chi N, Goldman SN, Lo DP, Harris IR, Popma SH, Sachs DH, Huang CA. Immunogenicity of umbilical cord tissue derived cells. Blood. 2008 Jan 01; 111(1):430-8. PMID: 17909081.
      View in: PubMed
    42. Horner BM, Randolph MA, Huang CA, Butler PE. Skin tolerance: in search of the Holy Grail. Transpl Int. 2008 Feb; 21(2):101-12. PMID: 17903184.
      View in: PubMed
    43. Cho PS, Lo DP, Wikiel KJ, Rowland HC, Coburn RC, McMorrow IM, Goodrich JG, Arn JS, Billiter RA, Houser SL, Shimizu A, Yang YG, Sachs DH, Huang CA. Establishment of transplantable porcine tumor cell lines derived from MHC-inbred miniature swine. Blood. 2007 Dec 01; 110(12):3996-4004. PMID: 17702898; PMCID: PMC2190613.
    44. Doucette K, Dor FJ, Wilkinson RA, Martin SI, Huang CA, Cooper DK, Sachs DH, Fishman JA. Gene expression of porcine lymphotrophic herpesvirus-1 in miniature Swine with posttransplant lymphoproliferative disorder. Transplantation. 2007 Jan 15; 83(1):87-90. PMID: 17220799.
      View in: PubMed
    45. Dor FJ, Ramirez ML, Parmar K, Altman EL, Huang CA, Down JD, Cooper DK. Primitive hematopoietic cell populations reside in the spleen: Studies in the pig, baboon, and human. Exp Hematol. 2006 Nov; 34(11):1573-82. PMID: 17046577.
      View in: PubMed
    46. Cina RA, Wikiel KJ, Lee PW, Cameron AM, Hettiarachy S, Rowland H, Goodrich J, Colby C, Spitzer TR, Neville DM, Huang CA. Stable multilineage chimerism without graft versus host disease following nonmyeloablative haploidentical hematopoietic cell transplantation. Transplantation. 2006 Jun 27; 81(12):1677-85. PMID: 16794534.
      View in: PubMed
    47. Dor FJ, Tseng YL, Kuwaki K, Gollackner B, Ramirez ML, Prabharasuth DD, Cina RA, Knosalla C, Nuhn MG, Houser SL, Huang CA, Ko DS, Cooper DK. Immunological unresponsiveness in chimeric miniature swine following MHC-mismatched spleen transplantation. Transplantation. 2005 Dec 27; 80(12):1791-804. PMID: 16378076.
      View in: PubMed
    48. Mathes DW, Solari MG, Randolph MA, Gazelle GS, Yamada K, Huang CA, Sachs DH, Lee WP. Long-term acceptance of renal allografts following prenatal inoculation with adult bone marrow. Transplantation. 2005 Nov 15; 80(9):1300-8. PMID: 16314799.
      View in: PubMed
    49. Lee PW, Cina RA, Randolph MA, Arellano R, Goodrich J, Rowland H, Huang CA, Sachs DH, Kim HB. In utero bone marrow transplantation induces kidney allograft tolerance across a full major histocompatibility complex barrier in Swine. Transplantation. 2005 May 15; 79(9):1084-90. PMID: 15880048.
      View in: PubMed
    50. Lee PW, Cina RA, Randolph MA, Goodrich J, Rowland H, Arellano R, Kim HB, Sachs DH, Huang CA. Stable multilineage chimerism across full MHC barriers without graft-versus-host disease following in utero bone marrow transplantation in pigs. Exp Hematol. 2005 Mar; 33(3):371-9. PMID: 15730861.
      View in: PubMed
    51. Cho PS, Mueller NJ, Cameron AM, Cina RA, Coburn RC, Hettiaratchy S, Melendy E, Neville DM, Patience C, Fishman JA, Sachs DH, Huang CA. Risk factors for the development of post-transplant lymphoproliferative disorder in a large animal model. Am J Transplant. 2004 Aug; 4(8):1274-82. PMID: 15268728.
      View in: PubMed
    52. Dor FJ, Doucette KE, Mueller NJ, Wilkinson RA, Bajwa JA, McMorrow IM, Tseng YL, Kuwaki K, Houser SL, Fishman JA, Cooper DK, Huang CA. Posttransplant lymphoproliferative disease after allogeneic transplantation of the spleen in miniature swine. Transplantation. 2004 Jul 27; 78(2):286-91. PMID: 15280692.
      View in: PubMed
    53. Hettiaratchy S, Melendy E, Randolph MA, Coburn RC, Neville DM, Sachs DH, Huang CA, Lee WP. Tolerance to composite tissue allografts across a major histocompatibility barrier in miniature swine. Transplantation. 2004 Feb 27; 77(4):514-21. PMID: 15084927.
      View in: PubMed
    54. Lima B, Gleit ZL, Cameron AM, Germana S, Murphy MC, Consorti R, Chang Q, Down JD, LeGuern C, Sachs DH, Huang CA. Engraftment of quiescent progenitors and conversion to full chimerism after nonmyelosuppressive conditioning and hematopoietic cell transplantation in miniature swine. Biol Blood Marrow Transplant. 2003 Sep; 9(9):571-82. PMID: 14506659.
      View in: PubMed
    55. Gleit ZL, Fuchimoto Y, Yamada K, Melendy E, Scheier-Dolberg R, Monajati L, Coburn RC, Neville DM, Sachs DH, Huang CA. Variable relationship between chimerism and tolerance after hematopoietic cell transplantation without myelosuppressive conditioning. Transplantation. 2002 Dec 15; 74(11):1535-44. PMID: 12490786.
      View in: PubMed
    56. Gleit ZL, Cameron AM, Fuchimoto Y, Melendy E, Monajati L, Coburn RC, Sachs DH, Huang CA. Persistent chimerism despite antidonor MHC in vitro responses in miniature swine following allogeneic hematopoietic cell transplantation. Transplantation. 2002 Nov 15; 74(9):1260-6. PMID: 12451263.
      View in: PubMed
    57. Haller GW, Lima B, Kunisaki SM, Germana S, Leguern C, Huang CA, Sachs DH. MHC alloantigens elicit secondary, but not primary, indirect in vitro proliferative responses. J Immunol. 2002 Oct 01; 169(7):3613-21. PMID: 12244152.
      View in: PubMed
    58. Heinz M, Huang CA, Emery DW, Giovino MA, LeGuern A, Kurilla-Mahon B, Theodore P, Arn JS, Sykes M, Mulligan R, Down JD, Sachs DH, Goodell MA. Use of CD9 expression to enrich for porcine hematopoietic progenitors. Exp Hematol. 2002 Jul; 30(7):809-15. PMID: 12135680.
      View in: PubMed
    59. Goltz M, Ericsson T, Patience C, Huang CA, Noack S, Sachs DH, Ehlers B. Sequence analysis of the genome of porcine lymphotropic herpesvirus 1 and gene expression during posttransplant lymphoproliferative disease of pigs. Virology. 2002 Mar 15; 294(2):383-93. PMID: 12009880.
      View in: PubMed
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