 Proto-Oncogene Proteins c-pim-1
"Proto-Oncogene Proteins c-pim-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Serine-threonine protein kinases that relay signals from CYTOKINE RECEPTORS and are involved in control of CELL GROWTH PROCESSES; CELL DIFFERENTIATION; and APOPTOSIS.
| Descriptor ID |
D051573
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| MeSH Number(s) |
D08.811.913.696.620.682.700.776 D12.776.624.664.700.191
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| Concept/Terms |
Proto-Oncogene Proteins c-pim-1- Proto-Oncogene Proteins c-pim-1
- Proto Oncogene Proteins c pim 1
- c-pim-1, Proto-Oncogene Proteins
- Pim-1 Kinase
- Kinase, Pim-1
- Pim 1 Kinase
- Proto-Oncogene Protein c-pim-1
- Proto Oncogene Protein c pim 1
- c-pim-1, Proto-Oncogene Protein
- Proto-Oncogene Protein pim-1
- Proto Oncogene Protein pim 1
- pim-1, Proto-Oncogene Protein
- c-pim-1 Protein
- c pim 1 Protein
- pim-1 Proto-Oncogene Protein
- pim 1 Proto Oncogene Protein
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-pim-1".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-pim-1".
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-pim-1" by people in this website by year, and whether "Proto-Oncogene Proteins c-pim-1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "Proto-Oncogene Proteins c-pim-1" by people in Profiles.
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Padi SKR, Singh N, Bearss JJ, Olive V, Song JH, Card?-Vila M, Kraft AS, Okumura K. Phosphorylation of DEPDC5, a component of the GATOR1 complex, releases inhibition of mTORC1 and promotes tumor growth. Proc Natl Acad Sci U S A. 2019 10 08; 116(41):20505-20510.
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Casillas AL, Toth RK, Sainz AG, Singh N, Desai AA, Kraft AS, Warfel NA. Hypoxia-Inducible PIM Kinase Expression Promotes Resistance to Antiangiogenic Agents. Clin Cancer Res. 2018 01 01; 24(1):169-180.
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Warfel NA, Sainz AG, Song JH, Kraft AS. PIM Kinase Inhibitors Kill Hypoxic Tumor Cells by Reducing Nrf2 Signaling and Increasing Reactive Oxygen Species. Mol Cancer Ther. 2016 07; 15(7):1637-47.
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Song JH, Padi SK, Luevano LA, Minden MD, DeAngelo DJ, Hardiman G, Ball LE, Warfel NA, Kraft AS. Insulin receptor substrate 1 is a substrate of the Pim protein kinases. Oncotarget. 2016 Apr 12; 7(15):20152-65.
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An N, Xiong Y, LaRue AC, Kraft AS, Cen B. Activation of Pim Kinases Is Sufficient to Promote Resistance to MET Small-Molecule Inhibitors. Cancer Res. 2015 Dec 15; 75(24):5318-28.
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Saurabh K, Scherzer MT, Shah PP, Mims AS, Lockwood WW, Kraft AS, Beverly LJ. The PIM family of oncoproteins: small kinases with huge implications in myeloid leukemogenesis and as therapeutic targets. Oncotarget. 2014 Sep 30; 5(18):8503-14.
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Cen B, Xiong Y, Song JH, Mahajan S, DuPont R, McEachern K, DeAngelo DJ, Cortes JE, Minden MD, Ebens A, Mims A, LaRue AC, Kraft AS. The Pim-1 protein kinase is an important regulator of MET receptor tyrosine kinase levels and signaling. Mol Cell Biol. 2014 Jul; 34(13):2517-32.
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An N, Lin YW, Mahajan S, Kellner JN, Wang Y, Li Z, Kraft AS, Kang Y. Pim1 serine/threonine kinase regulates the number and functions of murine hematopoietic stem cells. Stem Cells. 2013 Jun; 31(6):1202-12.
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Cen B, Mahajan S, Wang W, Kraft AS. Elevation of receptor tyrosine kinases by small molecule AKT inhibitors in prostate cancer is mediated by Pim-1. Cancer Res. 2013 Jun 01; 73(11):3402-11.
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An N, Kraft AS, Kang Y. Abnormal hematopoietic phenotypes in Pim kinase triple knockout mice. J Hematol Oncol. 2013 Jan 29; 6:12.
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