 Proto-Oncogene Proteins c-pim-1
"Proto-Oncogene Proteins c-pim-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Serine-threonine protein kinases that relay signals from CYTOKINE RECEPTORS and are involved in control of CELL GROWTH PROCESSES; CELL DIFFERENTIATION; and APOPTOSIS.
| Descriptor ID |
D051573
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| MeSH Number(s) |
D08.811.913.696.620.682.700.776 D12.776.624.664.700.191
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| Concept/Terms |
Proto-Oncogene Proteins c-pim-1- Proto-Oncogene Proteins c-pim-1
- Proto Oncogene Proteins c pim 1
- c-pim-1, Proto-Oncogene Proteins
- Pim-1 Kinase
- Kinase, Pim-1
- Pim 1 Kinase
- Proto-Oncogene Protein c-pim-1
- Proto Oncogene Protein c pim 1
- c-pim-1, Proto-Oncogene Protein
- Proto-Oncogene Protein pim-1
- Proto Oncogene Protein pim 1
- pim-1, Proto-Oncogene Protein
- c-pim-1 Protein
- c pim 1 Protein
- pim-1 Proto-Oncogene Protein
- pim 1 Proto Oncogene Protein
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-pim-1".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-pim-1".
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-pim-1" by people in this website by year, and whether "Proto-Oncogene Proteins c-pim-1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2009 | 3 | 0 | 3 | | 2010 | 2 | 0 | 2 | | 2013 | 2 | 0 | 2 | | 2014 | 3 | 0 | 3 | | 2015 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Proto-Oncogene Proteins c-pim-1" by people in Profiles.
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Casillas AL, Toth RK, Sainz AG, Singh N, Desai AA, Kraft AS, Warfel NA. Hypoxia-Inducible PIM Kinase Expression Promotes Resistance to Antiangiogenic Agents. Clin Cancer Res. 2018 01 01; 24(1):169-180.
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Warfel NA, Sainz AG, Song JH, Kraft AS. PIM Kinase Inhibitors Kill Hypoxic Tumor Cells by Reducing Nrf2 Signaling and Increasing Reactive Oxygen Species. Mol Cancer Ther. 2016 07; 15(7):1637-47.
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An N, Xiong Y, LaRue AC, Kraft AS, Cen B. Activation of Pim Kinases Is Sufficient to Promote Resistance to MET Small-Molecule Inhibitors. Cancer Res. 2015 Dec 15; 75(24):5318-28.
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Zemskova MY, Song JH, Cen B, Cerda-Infante J, Montecinos VP, Kraft AS. Regulation of prostate stromal fibroblasts by the PIM1 protein kinase. Cell Signal. 2015 Jan; 27(1):135-46.
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Saurabh K, Scherzer MT, Shah PP, Mims AS, Lockwood WW, Kraft AS, Beverly LJ. The PIM family of oncoproteins: small kinases with huge implications in myeloid leukemogenesis and as therapeutic targets. Oncotarget. 2014 Sep 30; 5(18):8503-14.
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Cen B, Xiong Y, Song JH, Mahajan S, DuPont R, McEachern K, DeAngelo DJ, Cortes JE, Minden MD, Ebens A, Mims A, LaRue AC, Kraft AS. The Pim-1 protein kinase is an important regulator of MET receptor tyrosine kinase levels and signaling. Mol Cell Biol. 2014 Jul; 34(13):2517-32.
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An N, Lin YW, Mahajan S, Kellner JN, Wang Y, Li Z, Kraft AS, Kang Y. Pim1 serine/threonine kinase regulates the number and functions of murine hematopoietic stem cells. Stem Cells. 2013 Jun; 31(6):1202-12.
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An N, Kraft AS, Kang Y. Abnormal hematopoietic phenotypes in Pim kinase triple knockout mice. J Hematol Oncol. 2013 Jan 29; 6:12.
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Wang M, Okamoto M, Domenico J, Han J, Ashino S, Shin YS, Gelfand EW. Inhibition of Pim1 kinase prevents peanut allergy by enhancing Runx3 expression and suppressing T(H)2 and T(H)17 T-cell differentiation. J Allergy Clin Immunol. 2012 Oct; 130(4):932-44.e12.
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Shin YS, Takeda K, Shiraishi Y, Jia Y, Wang M, Jackson L, Wright AD, Carter L, Robinson J, Hicken E, Gelfand EW. Inhibition of Pim1 kinase activation attenuates allergen-induced airway hyperresponsiveness and inflammation. Am J Respir Cell Mol Biol. 2012 Apr; 46(4):488-97.
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