 Osteopontin
"Osteopontin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A negatively-charged extracellular matrix protein that plays a role in the regulation of BONE metabolism and a variety of other biological functions. Cell signaling by osteopontin may occur through a cell adhesion sequence that recognizes INTEGRIN ALPHA-V BETA-3.
| Descriptor ID |
D053495
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| MeSH Number(s) |
D12.644.276.374.625 D12.776.395.700.837 D12.776.467.374.625 D12.776.860.300.762 D23.529.374.625
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| Concept/Terms |
Osteopontin- Osteopontin
- Sialoprotein 1
- Secreted Phosphoprotein 1
- Bone Sialoprotein 1
- Sialoprotein 1, Bone
- Bone Sialoprotein I
- Sialoprotein I, Bone
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Below are MeSH descriptors whose meaning is more general than "Osteopontin".
Below are MeSH descriptors whose meaning is more specific than "Osteopontin".
This graph shows the total number of publications written about "Osteopontin" by people in this website by year, and whether "Osteopontin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 | | 2003 | 0 | 2 | 2 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 4 | 4 | | 2006 | 0 | 3 | 3 | | 2009 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 2 | 1 | 3 | | 2013 | 1 | 0 | 1 | | 2016 | 1 | 1 | 2 |
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Below are the most recent publications written about "Osteopontin" by people in Profiles.
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Ahmed M, Sottnik JL, Dancik GM, Sahu D, Hansel DE, Theodorescu D, Schwartz MA. An Osteopontin/CD44 Axis in RhoGDI2-Mediated Metastasis Suppression. Cancer Cell. 2016 09 12; 30(3):432-443.
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Moran CS, Rush CM, Dougan T, Jose RJ, Biros E, Norman PE, Gera L, Golledge J. Modulation of Kinin B2 Receptor Signaling Controls Aortic Dilatation and Rupture in the Angiotensin II-Infused Apolipoprotein E-Deficient Mouse. Arterioscler Thromb Vasc Biol. 2016 05; 36(5):898-907.
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Kurzbach D, Platzer G, Schwarz TC, Henen MA, Konrat R, Hinderberger D. Cooperative unfolding of compact conformations of the intrinsically disordered protein osteopontin. Biochemistry. 2013 Aug 06; 52(31):5167-75.
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Nadlonek NA, Weyant MJ, Yu JA, Cleveland JC, Reece TB, Meng X, Fullerton DA. Radiation induces osteogenesis in human aortic valve interstitial cells. J Thorac Cardiovasc Surg. 2012 Dec; 144(6):1466-70.
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Anwar A, Li M, Frid MG, Kumar B, Gerasimovskaya EV, Riddle SR, McKeon BA, Thukaram R, Meyrick BO, Fini MA, Stenmark KR. Osteopontin is an endogenous modulator of the constitutively activated phenotype of pulmonary adventitial fibroblasts in hypoxic pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2012 Jul 01; 303(1):L1-L11.
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Cheema BS, Iyengar S, Ahluwalia TS, Kohli HS, Sharma R, Shah VN, Bhansali A, Sakhuja V, Khullar M. Association of an Osteopontin gene promoter polymorphism with susceptibility to diabetic nephropathy in Asian Indians. Clin Chim Acta. 2012 Oct 09; 413(19-20):1600-4.
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Mazali FC, Johnson RJ, Mazzali M. Use of uric acid-lowering agents limits experimental cyclosporine nephropathy. Nephron Exp Nephrol. 2012; 120(1):e12-9.
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Yang X, Meng X, Su X, Mauchley DC, Ao L, Cleveland JC, Fullerton DA. Bone morphogenic protein 2 induces Runx2 and osteopontin expression in human aortic valve interstitial cells: role of Smad1 and extracellular signal-regulated kinase 1/2. J Thorac Cardiovasc Surg. 2009 Oct; 138(4):1008-15.
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Gallant-Behm CL, Reno C, Tsao H, Hart DA. Genetic involvement in skin wound healing and scarring in domestic pigs: assessment of molecular expression patterns in (Yorkshire x Red Duroc) x Yorkshire backcross animals. J Invest Dermatol. 2007 Jan; 127(1):233-44.
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Le QT, Chen E, Salim A, Cao H, Kong CS, Whyte R, Donington J, Cannon W, Wakelee H, Tibshirani R, Mitchell JD, Richardson D, O'Byrne KJ, Koong AC, Giaccia AJ. An evaluation of tumor oxygenation and gene expression in patients with early stage non-small cell lung cancers. Clin Cancer Res. 2006 Mar 01; 12(5):1507-14.
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