 Lymphoid Enhancer-Binding Factor 1
"Lymphoid Enhancer-Binding Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A T-cell factor that plays an essential role in EMBRYONIC DEVELOPMENT.
| Descriptor ID |
D051821
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| MeSH Number(s) |
D12.776.260.730.500 D12.776.660.235.400.800.500 D12.776.664.235.400.800.500 D12.776.930.875.500
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| Concept/Terms |
Lymphoid Enhancer-Binding Factor 1- Lymphoid Enhancer-Binding Factor 1
- Lymphoid Enhancer Binding Factor 1
- LEF-1 Transcription Factor
- LEF 1 Transcription Factor
- Transcription Factor, LEF-1
- T Cell-Specific Transcription Factor 1-alpha
- T Cell Specific Transcription Factor 1 alpha
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Below are MeSH descriptors whose meaning is more general than "Lymphoid Enhancer-Binding Factor 1".
Below are MeSH descriptors whose meaning is more specific than "Lymphoid Enhancer-Binding Factor 1".
This graph shows the total number of publications written about "Lymphoid Enhancer-Binding Factor 1" by people in this website by year, and whether "Lymphoid Enhancer-Binding Factor 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 1 | 2 |
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Below are the most recent publications written about "Lymphoid Enhancer-Binding Factor 1" by people in Profiles.
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Gaillard D, Bowles SG, Salcedo E, Xu M, Millar SE, Barlow LA. ?-catenin is required for taste bud cell renewal and behavioral taste perception in adult mice. PLoS Genet. 2017 Aug; 13(8):e1006990.
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Xie Y, Kaufmann D, Moulton MJ, Panahi S, Gaynes JA, Watters HN, Zhou D, Xue HH, Fung CM, Levine EM, Letsou A, Brennan KC, Dorsky RI. Lef1-dependent hypothalamic neurogenesis inhibits anxiety. PLoS Biol. 2017 Aug; 15(8):e2002257.
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Xing S, Li F, Zeng Z, Zhao Y, Yu S, Shan Q, Li Y, Phillips FC, Maina PK, Qi HH, Liu C, Zhu J, Pope RM, Musselman CA, Zeng C, Peng W, Xue HH. Tcf1 and Lef1 transcription factors establish CD8(+) T cell identity through intrinsic HDAC activity. Nat Immunol. 2016 06; 17(6):695-703.
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An N, Lin YW, Mahajan S, Kellner JN, Wang Y, Li Z, Kraft AS, Kang Y. Pim1 serine/threonine kinase regulates the number and functions of murine hematopoietic stem cells. Stem Cells. 2013 Jun; 31(6):1202-12.
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Tokonzaba E, Chen J, Cheng X, Den Z, Ganeshan R, Muller EJ, Koch PJ. Plakoglobin as a regulator of desmocollin gene expression. J Invest Dermatol. 2013 Dec; 133(12):2732-2740.
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Malhotra N, Narayan K, Cho OH, Sylvia KE, Yin C, Melichar H, Rashighi M, Lefebvre V, Harris JE, Berg LJ, Kang J. A network of high-mobility group box transcription factors programs innate interleukin-17 production. Immunity. 2013 Apr 18; 38(4):681-93.
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Zhang Z, Florez S, Gutierrez-Hartmann A, Martin JF, Amendt BA. MicroRNAs regulate pituitary development, and microRNA 26b specifically targets lymphoid enhancer factor 1 (Lef-1), which modulates pituitary transcription factor 1 (Pit-1) expression. J Biol Chem. 2010 Nov 05; 285(45):34718-28.
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Cordray P, Satterwhite DJ. TGF-beta induces novel Lef-1 splice variants through a Smad-independent signaling pathway. Dev Dyn. 2005 Apr; 232(4):969-78.
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Supekova L, Pezacki JP, Su AI, Loweth CJ, Riedl R, Geierstanger B, Schultz PG, Wemmer DE. Genomic effects of polyamide/DNA interactions on mRNA expression. Chem Biol. 2002 Jul; 9(7):821-7.
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Williams BO, Barish GD, Klymkowsky MW, Varmus HE. A comparative evaluation of beta-catenin and plakoglobin signaling activity. Oncogene. 2000 Nov 23; 19(50):5720-8.
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