 Fibroblast Growth Factor 8
"Fibroblast Growth Factor 8" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fibroblast growth factor that preferentially activates FIBROBLAST GROWTH FACTOR RECEPTOR 4. It was initially identified as an androgen-induced growth factor and plays a role in regulating growth of human BREAST NEOPLASMS and PROSTATIC NEOPLASMS.
| Descriptor ID |
D051524
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| MeSH Number(s) |
D12.644.276.624.180 D12.776.467.624.180 D23.529.624.180
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| Concept/Terms |
Fibroblast Growth Factor 8- Fibroblast Growth Factor 8
- Androgen-Induced Growth Factor
- Androgen Induced Growth Factor
- Growth Factor, Androgen-Induced
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Below are MeSH descriptors whose meaning is more general than "Fibroblast Growth Factor 8".
Below are MeSH descriptors whose meaning is more specific than "Fibroblast Growth Factor 8".
This graph shows the total number of publications written about "Fibroblast Growth Factor 8" by people in this website by year, and whether "Fibroblast Growth Factor 8" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 2 | 2 | | 2008 | 2 | 0 | 2 | | 2010 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2014 | 2 | 0 | 2 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Fibroblast Growth Factor 8" by people in Profiles.
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Schmidt L, Taiyab A, Melvin VS, Jones KL, Williams T. Increased FGF8 signaling promotes chondrogenic rather than osteogenic development in the embryonic skull. Dis Model Mech. 2018 06 15; 11(6).
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Green RM, Feng W, Phang T, Fish JL, Li H, Spritz RA, Marcucio RS, Hooper J, Jamniczky H, Hallgrímsson B, Williams T. Tfap2a-dependent changes in mouse facial morphology result in clefting that can be ameliorated by a reduction in Fgf8 gene dosage. Dis Model Mech. 2015 Jan; 8(1):31-43.
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Brooks LR, Pals HL, Enix CL, Woolaver RA, Paul ED, Lowry CA, Tsai PS. Fibroblast growth factor 8 deficiency compromises the functional response of the serotonergic system to stress. PLoS One. 2014; 9(7):e101420.
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Tata BK, Chung WC, Brooks LR, Kavanaugh SI, Tsai PS. Fibroblast growth factor signaling deficiencies impact female reproduction and kisspeptin neurons in mice. Biol Reprod. 2012 Apr; 86(4):119.
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McCabe MJ, Gaston-Massuet C, Tziaferi V, Gregory LC, Alatzoglou KS, Signore M, Puelles E, Gerrelli D, Farooqi IS, Raza J, Walker J, Kavanaugh SI, Tsai PS, Pitteloud N, Martinez-Barbera JP, Dattani MT. Novel FGF8 mutations associated with recessive holoprosencephaly, craniofacial defects, and hypothalamo-pituitary dysfunction. J Clin Endocrinol Metab. 2011 Oct; 96(10):E1709-18.
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Reid BS, Yang H, Melvin VS, Taketo MM, Williams T. Ectodermal Wnt/ß-catenin signaling shapes the mouse face. Dev Biol. 2011 Jan 15; 349(2):261-9.
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Falardeau J, Chung WC, Beenken A, Raivio T, Plummer L, Sidis Y, Jacobson-Dickman EE, Eliseenkova AV, Ma J, Dwyer A, Quinton R, Na S, Hall JE, Huot C, Alois N, Pearce SH, Cole LW, Hughes V, Mohammadi M, Tsai P, Pitteloud N. Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice. J Clin Invest. 2008 Aug; 118(8):2822-31.
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Chung WC, Moyle SS, Tsai PS. Fibroblast growth factor 8 signaling through fibroblast growth factor receptor 1 is required for the emergence of gonadotropin-releasing hormone neurons. Endocrinology. 2008 Oct; 149(10):4997-5003.
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Liu A, Li JY, Bromleigh C, Lao Z, Niswander LA, Joyner AL. FGF17b and FGF18 have different midbrain regulatory properties from FGF8b or activated FGF receptors. Development. 2003 Dec; 130(25):6175-85.
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Draper BW, Stock DW, Kimmel CB. Zebrafish fgf24 functions with fgf8 to promote posterior mesodermal development. Development. 2003 Oct; 130(19):4639-54.
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