 Replicon
"Replicon" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Any DNA sequence capable of independent replication or a molecule that possesses a REPLICATION ORIGIN and which is therefore potentially capable of being replicated in a suitable cell. (Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
| Descriptor ID |
D012093
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| MeSH Number(s) |
G05.360.340.024.745
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| Concept/Terms |
Replicon- Replicon
- Replicons
- Replication Unit
- Replication Units
- Unit, Replication
- Units, Replication
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Below are MeSH descriptors whose meaning is more general than "Replicon".
Below are MeSH descriptors whose meaning is more specific than "Replicon".
This graph shows the total number of publications written about "Replicon" by people in this website by year, and whether "Replicon" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 1 | 1 | 2 | | 2008 | 2 | 0 | 2 | | 2009 | 1 | 1 | 2 | | 2011 | 0 | 1 | 1 | | 2013 | 1 | 1 | 2 | | 2017 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Replicon" by people in Profiles.
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Scholte FEM, Spengler JR, Welch SR, Harmon JR, Coleman-McCray JD, Freitas BT, Kainulainen MH, Pegan SD, Nichol ST, Bergeron É, Spiropoulou CF. Single-dose replicon particle vaccine provides complete protection against Crimean-Congo hemorrhagic fever virus in mice. Emerg Microbes Infect. 2019; 8(1):575-578.
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Agnoli K, Freitag R, Gomes MC, Jenul C, Suppiger A, Mannweiler O, Frauenknecht C, Janser D, Vergunst AC, Eberl L. Use of Synthetic Hybrid Strains To Determine the Role of Replicon 3 in Virulence of the Burkholderia cepacia Complex. Appl Environ Microbiol. 2017 07 01; 83(13).
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Agnoli K, Frauenknecht C, Freitag R, Schwager S, Jenul C, Vergunst A, Carlier A, Eberl L. The third replicon of members of the Burkholderia cepacia Complex, plasmid pC3, plays a role in stress tolerance. Appl Environ Microbiol. 2014 Feb; 80(4):1340-8.
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Gaggioli V, Le Viet B, Germe T, Hyrien O. DNA topoisomerase IIa controls replication origin cluster licensing and firing time in Xenopus egg extracts. Nucleic Acids Res. 2013 Aug; 41(15):7313-31.
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Copley SD, Rokicki J, Turner P, Daligault H, Nolan M, Land M. The whole genome sequence of Sphingobium chlorophenolicum L-1: insights into the evolution of the pentachlorophenol degradation pathway. Genome Biol Evol. 2012; 4(2):184-98.
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Parsons J, Castaldi MP, Dutta S, Dibrov SM, Wyles DL, Hermann T. Conformational inhibition of the hepatitis C virus internal ribosome entry site RNA. Nat Chem Biol. 2009 Nov; 5(11):823-5.
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Wyles DL, Kaihara KA, Korba BE, Schooley RT, Beadle JR, Hostetler KY. The octadecyloxyethyl ester of (S)-9-[3-hydroxy-2-(phosphonomethoxy) propyl]adenine is a potent and selective inhibitor of hepatitis C virus replication in genotype 1A, 1B, and 2A replicons. Antimicrob Agents Chemother. 2009 Jun; 53(6):2660-2.
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Labit H, Perewoska I, Germe T, Hyrien O, Marheineke K. DNA replication timing is deterministic at the level of chromosomal domains but stochastic at the level of replicons in Xenopus egg extracts. Nucleic Acids Res. 2008 Oct; 36(17):5623-34.
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Kent SJ, De Rose R, Mokhonov VV, Mokhonova EI, Fernandez CS, Alcantara S, Rollman E, Mason RD, Loh L, Peut V, Reece JC, Wang XJ, Wilson KM, Suhrbier A, Khromykh A. Evaluation of recombinant Kunjin replicon SIV vaccines for protective efficacy in macaques. Virology. 2008 May 10; 374(2):528-34.
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Wyles DL, Kaihara KA, Vaida F, Schooley RT. Synergy of small molecular inhibitors of hepatitis C virus replication directed at multiple viral targets. J Virol. 2007 Mar; 81(6):3005-8.
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