 Ion Channel Gating
"Ion Channel Gating" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The opening and closing of ion channels due to a stimulus. The stimulus can be a change in membrane potential (voltage-gated), drugs or chemical transmitters (ligand-gated), or a mechanical deformation. Gating is thought to involve conformational changes of the ion channel which alters selective permeability.
| Descriptor ID |
D015640
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| MeSH Number(s) |
G02.111.820.400 G04.835.400 G07.265.625
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| Concept/Terms |
Ion Channel Gating- Ion Channel Gating
- Gating, Ion Channel
- Gatings, Ion Channel
- Ion Channel Gatings
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Below are MeSH descriptors whose meaning is more general than "Ion Channel Gating".
Below are MeSH descriptors whose meaning is more specific than "Ion Channel Gating".
This graph shows the total number of publications written about "Ion Channel Gating" by people in this website by year, and whether "Ion Channel Gating" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 1 | 1 | 2 | | 1992 | 2 | 1 | 3 | | 1994 | 0 | 4 | 4 | | 1995 | 1 | 0 | 1 | | 1996 | 4 | 2 | 6 | | 1997 | 0 | 4 | 4 | | 1998 | 2 | 3 | 5 | | 1999 | 2 | 6 | 8 | | 2000 | 2 | 2 | 4 | | 2001 | 0 | 1 | 1 | | 2002 | 2 | 5 | 7 | | 2003 | 1 | 3 | 4 | | 2004 | 1 | 1 | 2 | | 2005 | 3 | 3 | 6 | | 2006 | 0 | 2 | 2 | | 2007 | 1 | 1 | 2 | | 2008 | 1 | 7 | 8 | | 2009 | 3 | 2 | 5 | | 2010 | 3 | 2 | 5 | | 2011 | 1 | 1 | 2 | | 2012 | 3 | 1 | 4 | | 2013 | 2 | 0 | 2 | | 2014 | 0 | 1 | 1 | | 2015 | 1 | 1 | 2 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 1 | 2 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ion Channel Gating" by people in Profiles.
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Tyagi S, Bendrick TR, Filipova D, Papadopoulos S, Bannister RA. A mutation in CaV2.1 linked to a severe neurodevelopmental disorder impairs channel gating. J Gen Physiol. 2019 06 03; 151(6):850-859.
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Romanov RA, Lasher RS, High B, Savidge LE, Lawson A, Rogachevskaja OA, Zhao H, Rogachevsky VV, Bystrova MF, Churbanov GD, Adameyko I, Harkany T, Yang R, Kidd GJ, Marambaud P, Kinnamon JC, Kolesnikov SS, Finger TE. Chemical synapses without synaptic vesicles: Purinergic neurotransmission through a CALHM1 channel-mitochondrial signaling complex. Sci Signal. 2018 05 08; 11(529).
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Bruni GN, Weekley RA, Dodd BJT, Kralj JM. Voltage-gated calcium flux mediates Escherichia coli mechanosensation. Proc Natl Acad Sci U S A. 2017 08 29; 114(35):9445-9450.
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Lorca RA, Ma X, England SK. The unique N-terminal sequence of the BKCa channel a-subunit determines its modulation by ß-subunits. PLoS One. 2017; 12(7):e0182068.
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Nematian-Ardestani E, Jarerattanachat V, Aryal P, Sansom MSP, Tucker SJ. The effects of stretch activation on ionic selectivity of the TREK-2 K2P K+ channel. Channels (Austin). 2017 Sep 03; 11(5):482-486.
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Aryal P, Jarerattanachat V, Clausen MV, Schewe M, McClenaghan C, Argent L, Conrad LJ, Dong YY, Pike ACW, Carpenter EP, Baukrowitz T, Sansom MSP, Tucker SJ. Bilayer-Mediated Structural Transitions Control Mechanosensitivity of the TREK-2 K2P Channel. Structure. 2017 05 02; 25(5):708-718.e2.
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McClenaghan C, Schewe M, Aryal P, Carpenter EP, Baukrowitz T, Tucker SJ. Polymodal activation of the TREK-2 K2P channel produces structurally distinct open states. J Gen Physiol. 2016 06; 147(6):497-505.
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Zhang X, Hothi JS, Zhang YH, Srinivasan S, Stokes DC, Zhang W. c.3623G?>?A mutation encodes a CFTR protein with impaired channel function. Respir Res. 2016 Jan 22; 17:8.
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Bannister RA. Bridging the myoplasmic gap II: more recent advances in skeletal muscle excitation-contraction coupling. J Exp Biol. 2016 Jan; 219(Pt 2):175-82.
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Ye W, Chang RB, Bushman JD, Tu YH, Mulhall EM, Wilson CE, Cooper AJ, Chick WS, Hill-Eubanks DC, Nelson MT, Kinnamon SC, Liman ER. The K+ channel KIR2.1 functions in tandem with proton influx to mediate sour taste transduction. Proc Natl Acad Sci U S A. 2016 Jan 12; 113(2):E229-38.
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