Ion Channel Gating
"Ion Channel Gating" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The opening and closing of ion channels due to a stimulus. The stimulus can be a change in membrane potential (voltage-gated), drugs or chemical transmitters (ligand-gated), or a mechanical deformation. Gating is thought to involve conformational changes of the ion channel which alters selective permeability.
Descriptor ID |
D015640
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MeSH Number(s) |
G02.111.820.400 G04.835.400 G07.265.625
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Concept/Terms |
Ion Channel Gating- Ion Channel Gating
- Gating, Ion Channel
- Gatings, Ion Channel
- Ion Channel Gatings
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Below are MeSH descriptors whose meaning is more general than "Ion Channel Gating".
Below are MeSH descriptors whose meaning is more specific than "Ion Channel Gating".
This graph shows the total number of publications written about "Ion Channel Gating" by people in this website by year, and whether "Ion Channel Gating" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1992 | 0 | 1 | 1 | 1994 | 0 | 1 | 1 | 1996 | 4 | 1 | 5 | 1997 | 0 | 3 | 3 | 1998 | 1 | 2 | 3 | 1999 | 1 | 6 | 7 | 2001 | 0 | 1 | 1 | 2002 | 1 | 4 | 5 | 2003 | 0 | 2 | 2 | 2004 | 1 | 1 | 2 | 2005 | 2 | 2 | 4 | 2006 | 0 | 2 | 2 | 2007 | 0 | 1 | 1 | 2008 | 1 | 3 | 4 | 2009 | 2 | 1 | 3 | 2010 | 1 | 2 | 3 | 2012 | 2 | 0 | 2 | 2014 | 0 | 1 | 1 | 2015 | 0 | 1 | 1 | 2017 | 1 | 0 | 1 | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ion Channel Gating" by people in Profiles.
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Klipp RC, Cullinan MM, Bankston JR. Insights into the molecular mechanisms underlying the inhibition of acid-sensing ion channel 3 gating by stomatin. J Gen Physiol. 2020 03 02; 152(3).
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Bruni GN, Weekley RA, Dodd BJT, Kralj JM. Voltage-gated calcium flux mediates Escherichia coli mechanosensation. Proc Natl Acad Sci U S A. 2017 08 29; 114(35):9445-9450.
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Aryal P, Jarerattanachat V, Clausen MV, Schewe M, McClenaghan C, Argent L, Conrad LJ, Dong YY, Pike ACW, Carpenter EP, Baukrowitz T, Sansom MSP, Tucker SJ. Bilayer-Mediated Structural Transitions Control Mechanosensitivity of the TREK-2 K2P Channel. Structure. 2017 05 02; 25(5):708-718.e2.
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Zhang X, Hothi JS, Zhang YH, Srinivasan S, Stokes DC, Zhang W. c.3623G?>?A mutation encodes a CFTR protein with impaired channel function. Respir Res. 2016 Jan 22; 17:8.
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Ye W, Chang RB, Bushman JD, Tu YH, Mulhall EM, Wilson CE, Cooper AJ, Chick WS, Hill-Eubanks DC, Nelson MT, Kinnamon SC, Liman ER. The K+ channel KIR2.1 functions in tandem with proton influx to mediate sour taste transduction. Proc Natl Acad Sci U S A. 2016 Jan 12; 113(2):E229-38.
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Trick JL, Aryal P, Tucker SJ, Sansom MS. Molecular simulation studies of hydrophobic gating in nanopores and ion channels. Biochem Soc Trans. 2015 Apr; 43(2):146-50.
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Dong YY, Pike AC, Mackenzie A, McClenaghan C, Aryal P, Dong L, Quigley A, Grieben M, Goubin S, Mukhopadhyay S, Ruda GF, Clausen MV, Cao L, Brennan PE, Burgess-Brown NA, Sansom MS, Tucker SJ, Carpenter EP. K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac. Science. 2015 Mar 13; 347(6227):1256-9.
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López F, Delgado R, López R, Bacigalupo J, Restrepo D. Transduction for pheromones in the main olfactory epithelium is mediated by the Ca2+ -activated channel TRPM5. J Neurosci. 2014 Feb 26; 34(9):3268-78.
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Zhang Z, Yu H, Huang J, Faouzi M, Schmitz C, Penner R, Fleig A. The TRPM6 kinase domain determines the Mg·ATP sensitivity of TRPM7/M6 heteromeric ion channels. J Biol Chem. 2014 Feb 21; 289(8):5217-27.
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Liao Z, Lockhead D, St Clair JR, Larson ED, Wilson CE, Proenza C. Cellular context and multiple channel domains determine cAMP sensitivity of HCN4 channels: ligand-independent relief of autoinhibition in HCN4. J Gen Physiol. 2012 Nov; 140(5):557-66.
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