 Long QT Syndrome
"Long QT Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.
| Descriptor ID |
D008133
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| MeSH Number(s) |
C14.280.067.565 C14.280.123.625 C16.131.240.400.715 C23.550.073.547
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Long QT Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Long QT Syndrome".
This graph shows the total number of publications written about "Long QT Syndrome" by people in this website by year, and whether "Long QT Syndrome" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 2 | 0 | 2 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 1 | 2 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2013 | 4 | 1 | 5 | | 2014 | 3 | 0 | 3 | | 2015 | 2 | 1 | 3 | | 2016 | 0 | 2 | 2 | | 2017 | 2 | 0 | 2 | | 2018 | 1 | 1 | 2 | | 2019 | 3 | 0 | 3 | | 2021 | 5 | 0 | 5 | | 2022 | 3 | 1 | 4 | | 2023 | 3 | 0 | 3 | | 2024 | 1 | 0 | 1 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Long QT Syndrome" by people in Profiles.
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Trinkley KE, Simon ST, Rosenberg MA. Impact of an Alert-Based Inpatient Clinical Decision Support Tool to Prevent Drug-Induced Long QT Syndrome: Large-Scale, System-Wide Observational Study. J Med Internet Res. 2025 Apr 14; 27:e68256.
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Simon ST, Lin M, Trinkley KE, Aleong R, Rafaels N, Crooks KR, Reiter MJ, Gignoux CR, Rosenberg MA. A polygenic risk score for the QT interval is an independent predictor of drug-induced QT prolongation. PLoS One. 2024; 19(6):e0303261.
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Lowe RN, Wright G, Olivas L, Teel C, Suresh K, Macke LB, Sieja A, Rosenberg MA, Trinkley KE. Evaluating the prescribing and monitoring of medications associated with QTc-prolongation in the ambulatory care setting. J Eval Clin Pract. 2024 04; 30(3):385-392.
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Kaizer AM, Winbo A, Clur SB, Etheridge SP, Ackerman MJ, Horigome H, Herberg U, Dagradi F, Spazzolini C, Killen SAS, Wacker-Gussmann A, Wilde AAM, Sinkovskaya E, Abuhamad A, Torchio M, Ng CA, Rydberg A, Schwartz PJ, Cuneo BF. Effects of cohort, genotype, variant, and maternal ?-blocker treatment on foetal heart rate predictors of inherited long QT syndrome. Europace. 2023 11 02; 25(11).
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Arsava EM, Chang K, Tawakol A, Loggia ML, Goldstein JN, Brown J, Park KY, Singhal AB, Kalpathy-Cramer J, Sorensen AG, Rosen BR, Samuels MA, Ay H. Stroke-Related Visceral Alterations: A Voxel-Based Neuroanatomic Localization Study. Ann Neurol. 2023 12; 94(6):1155-1163.
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Crotti L, Spazzolini C, Nyegaard M, Overgaard MT, Kotta MC, Dagradi F, Sala L, Aiba T, Ayers MD, Baban A, Barc J, Beach CM, Behr ER, Bos JM, Cerrone M, Covi P, Cuneo B, Denjoy I, Donner B, Elbert A, Eliasson H, Etheridge SP, Fukuyama M, Girolami F, Hamilton R, Horie M, Iascone M, Jim?nez-Jaimez J, Jensen HK, Kannankeril PJ, Kaski JP, Makita N, Mu?oz-Esparza C, Odland HH, Ohno S, Papagiannis J, Porretta AP, Prandstetter C, Probst V, Robyns T, Rosenthal E, Ros?s-Noguer F, Sekarski N, Singh A, Spentzou G, Stute F, Tfelt-Hansen J, Till J, Tobert KE, Vinocur JM, Webster G, Wilde AAM, Wolf CM, Ackerman MJ, Schwartz PJ. Clinical presentation of calmodulin mutations: the International Calmodulinopathy Registry. Eur Heart J. 2023 09 14; 44(35):3357-3370.
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Simon ST, Trinkley KE, Malone DC, Rosenberg MA. Interpretable Machine Learning Prediction of Drug-Induced QT Prolongation: Electronic Health Record Analysis. J Med Internet Res. 2022 12 01; 24(12):e42163.
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Stansauk J, Fidell A, Benke T, Schaffer M, Demarest ST. Analysis of electrocardiograms in individuals with CDKL5 deficiency disorder. Am J Med Genet A. 2023 Jan; 191(1):108-111.
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Sanderson JL, Freund RK, Castano AM, Benke TA, Dell'Acqua ML. The CaV1.2 G406R mutation decreases synaptic inhibition and alters L-type Ca2+ channel-dependent LTP at hippocampal synapses in a mouse model of Timothy Syndrome. Neuropharmacology. 2022 Dec 01; 220:109271.
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Wempe MF. New Insights into Ion Channels: Predicting hERG-Drug Interactions. Int J Mol Sci. 2022 Sep 14; 23(18).
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