 Nicotine
"Nicotine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
| Descriptor ID |
D009538
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| MeSH Number(s) |
D03.132.760.570 D03.383.725.518
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nicotine".
Below are MeSH descriptors whose meaning is more specific than "Nicotine".
This graph shows the total number of publications written about "Nicotine" by people in this website by year, and whether "Nicotine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 2 | 0 | 2 | | 1994 | 0 | 1 | 1 | | 1995 | 4 | 1 | 5 | | 1996 | 0 | 2 | 2 | | 1997 | 2 | 0 | 2 | | 1998 | 3 | 0 | 3 | | 1999 | 4 | 1 | 5 | | 2000 | 4 | 4 | 8 | | 2001 | 3 | 0 | 3 | | 2002 | 3 | 0 | 3 | | 2003 | 6 | 4 | 10 | | 2004 | 10 | 1 | 11 | | 2005 | 6 | 1 | 7 | | 2006 | 3 | 3 | 6 | | 2007 | 4 | 3 | 7 | | 2008 | 2 | 2 | 4 | | 2009 | 3 | 2 | 5 | | 2010 | 4 | 1 | 5 | | 2011 | 5 | 0 | 5 | | 2012 | 5 | 4 | 9 | | 2013 | 5 | 2 | 7 | | 2014 | 4 | 1 | 5 | | 2015 | 5 | 2 | 7 | | 2016 | 1 | 0 | 1 | | 2017 | 5 | 3 | 8 | | 2018 | 6 | 2 | 8 | | 2019 | 2 | 2 | 4 | | 2020 | 6 | 4 | 10 | | 2021 | 3 | 3 | 6 | | 2022 | 1 | 4 | 5 | | 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nicotine" by people in Profiles.
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Mize TJ, Funkhouser SA, Buck JM, Stitzel JA, Ehringer MA, Evans LM. Testing Association of Previously Implicated Gene Sets and Gene-Networks in Nicotine Exposed Mouse Models with Human Smoking Phenotypes. Nicotine Tob Res. 2023 04 06; 25(5):1030-1038.
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Novick AM, Duffy KA, Johnson RL, Sammel MD, Cao W, Strasser AA, Sofuoglu M, Kuzma A, Loughead J, Epperson CN. Progesterone Increases Nicotine Withdrawal and Anxiety in Male but Not Female Smokers During Brief Abstinence. Nicotine Tob Res. 2022 11 12; 24(12):1898-1905.
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Esther CR, O'Neal WK, Alexis NE, Koch AL, Cooper CB, Barjaktarevic I, Raffield LM, Bowler RP, Comellas AP, Peters SP, Hastie AT, Curtis JL, Ronish B, Ortega VE, Wells JM, Halper-Stromberg E, Rennard SI, Boucher RC. Prolonged, physiologically relevant nicotine concentrations in the airways of smokers. Am J Physiol Lung Cell Mol Physiol. 2023 01 01; 324(1):L32-L37.
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Novick AM, Duffy KA, Johnson RL, Sammel MD, Cao W, Strasser AA, Sofuoglu M, Kuzma A, Loughead J, Morrow AL, Epperson CN. Effect of progesterone administration in male and female smokers on nicotine withdrawal and neural response to smoking cues: role of progesterone conversion to allopregnanolone. Biol Sex Differ. 2022 10 23; 13(1):60.
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Hinds DM, Nick HJ, Vallin TM, Bloomquist LA, Christeson S, Bratcher PE, Cooper EH, Brinton JT, Bosco-Lauth A, White CW. Acute vaping in a golden Syrian hamster causes inflammatory response transcriptomic changes. Am J Physiol Lung Cell Mol Physiol. 2022 11 01; 323(5):L525-L535.
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Quijano Card? NA, Shaw J, Carter C, Kim S, Stitzel JA, Venkatesh SK, Ramchandani VA, De Biasi M. Mutation of the a5 nicotinic acetylcholine receptor subunit increases ethanol and nicotine consumption in adolescence and impacts adult drug consumption. Neuropharmacology. 2022 09 15; 216:109170.
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Flores-Bellver M, Mighty J, Aparicio-Domingo S, Li KV, Shi C, Zhou J, Cobb H, McGrath P, Michelis G, Lenhart P, Bilousova G, Heissel S, Rudy MJ, Coughlan C, Goodspeed AE, Becerra SP, Redenti S, Canto-Soler MV. Extracellular vesicles released by human retinal pigment epithelium mediate increased polarised secretion of drusen proteins in response to AMD stressors. J Extracell Vesicles. 2021 11; 10(13):e12165.
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Cunningham JK, Solomon TGA, Ritchey J, Muramoto ML. Dual Diagnosis and Alcohol/Nicotine Use Disorders: Native American and White Hospital Patients in 3 States. Am J Prev Med. 2022 02; 62(2):e107-e116.
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Bhargava M, Mroz MM, Maier LA. Smoke Signals: Promise of Nicotine as a Treatment for Pulmonary Sarcoidosis. Chest. 2021 10; 160(4):1169-1170.
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Buck JM, Yu L, Knopik VS, Stitzel JA. DNA methylome perturbations: an epigenetic basis for the emergingly heritable neurodevelopmental abnormalities associated with maternal smoking and maternal nicotine exposure?. Biol Reprod. 2021 09 14; 105(3):644-666.
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