 Interferon-gamma
"Interferon-gamma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.
| Descriptor ID |
D007371
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| MeSH Number(s) |
D12.644.276.374.440.893 D12.644.276.374.480.615.350 D12.776.467.374.440.893 D12.776.467.374.480.615.350 D23.529.374.440.893 D23.529.374.480.615.350
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| Concept/Terms |
Interferon-gamma- Interferon-gamma
- gamma-Interferon
- Interferon, Immune
- Immune Interferon
- Type II Interferon
- Interferon, Type II
- Interferon Type II
- Interferon, gamma
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Below are MeSH descriptors whose meaning is more general than "Interferon-gamma".
Below are MeSH descriptors whose meaning is more specific than "Interferon-gamma".
This graph shows the total number of publications written about "Interferon-gamma" by people in this website by year, and whether "Interferon-gamma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1989 | 4 | 2 | 6 | | 1990 | 4 | 9 | 13 | | 1991 | 1 | 2 | 3 | | 1992 | 1 | 4 | 5 | | 1993 | 5 | 4 | 9 | | 1994 | 1 | 10 | 11 | | 1995 | 4 | 4 | 8 | | 1996 | 3 | 10 | 13 | | 1997 | 2 | 2 | 4 | | 1998 | 9 | 13 | 22 | | 1999 | 3 | 8 | 11 | | 2000 | 9 | 8 | 17 | | 2001 | 8 | 19 | 27 | | 2002 | 9 | 12 | 21 | | 2003 | 12 | 16 | 28 | | 2004 | 6 | 13 | 19 | | 2005 | 7 | 18 | 25 | | 2006 | 7 | 14 | 21 | | 2007 | 13 | 15 | 28 | | 2008 | 5 | 21 | 26 | | 2009 | 10 | 12 | 22 | | 2010 | 9 | 17 | 26 | | 2011 | 5 | 19 | 24 | | 2012 | 4 | 18 | 22 | | 2013 | 7 | 11 | 18 | | 2014 | 3 | 14 | 17 | | 2015 | 5 | 15 | 20 | | 2016 | 6 | 11 | 17 | | 2017 | 1 | 6 | 7 | | 2018 | 1 | 4 | 5 |
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Below are the most recent publications written about "Interferon-gamma" by people in Profiles.
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Kaplanov I, Carmi Y, Kornetsky R, Shemesh A, Shurin GV, Shurin MR, Dinarello CA, Voronov E, Apte RN. Blocking IL-1ß reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation. Proc Natl Acad Sci U S A. 2019 01 22; 116(4):1361-1369.
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Chan ED. Reduced IFN-? in Patients with Pulmonary Nontuberculous Mycobacterial Disease: Potentially Multiple Causes. Am J Respir Cell Mol Biol. 2018 07; 59(1):130-131.
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Pennell CA, Barnum JL, McDonald-Hyman CS, Panoskaltsis-Mortari A, Riddle MJ, Xiong Z, Loschi M, Thangavelu G, Campbell HM, Storlie MD, Refaeli Y, Furlan SN, Jensen MC, Kean LS, Miller JS, Tolar J, Osborn MJ, Blazar BR. Human CD19-Targeted Mouse T Cells Induce B Cell Aplasia and Toxicity in Human CD19 Transgenic Mice. Mol Ther. 2018 06 06; 26(6):1423-1434.
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Faddoul G, Nadkarni GN, Bridges ND, Goebel J, Hricik DE, Formica R, Menon MC, Morrison Y, Murphy B, Newell K, Nickerson P, Poggio ED, Rush D, Heeger PS. Analysis of Biomarkers Within the Initial 2 Years Posttransplant and 5-Year Kidney Transplant Outcomes: Results From Clinical Trials in Organ Transplantation-17. Transplantation. 2018 04; 102(4):673-680.
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Nahomi RB, Sampathkumar S, Myers AM, Elghazi L, Smith DG, Tang J, Lee CA, Kern TS, Nagaraj RH, Fort PE. The Absence of Indoleamine 2,3-Dioxygenase Inhibits Retinal Capillary Degeneration in Diabetic Mice. Invest Ophthalmol Vis Sci. 2018 04 01; 59(5):2042-2053.
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Pugh JL, Nemat-Gorgani N, Norman PJ, Guethlein LA, Parham P. Human NK Cells Downregulate Zap70 and Syk in Response to Prolonged Activation or DNA Damage. J Immunol. 2018 02 01; 200(3):1146-1158.
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Vajravelu RK, Osterman MT, Aberra FN, Roy JA, Lichtenstein GR, Mamtani R, Goldberg DS, Lewis JD, Scott FI. Indeterminate QuantiFERON-TB Gold Increases Likelihood of Inflammatory Bowel Disease Treatment Delay and Hospitalization. Inflamm Bowel Dis. 2017 12 19; 24(1):217-226.
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Ellison MA, Gearheart CM, Porter CC, Ambruso DR. IFN-? alters the expression of diverse immunity related genes in a cell culture model designed to represent maturing neutrophils. PLoS One. 2017; 12(10):e0185956.
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Weinberg A, Canniff J, Rouphael N, Mehta A, Mulligan M, Whitaker JA, Levin MJ. Varicella-Zoster Virus-Specific Cellular Immune Responses to the Live Attenuated Zoster Vaccine in Young and Older Adults. J Immunol. 2017 07 15; 199(2):604-612.
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Vaitaitis GM, Yussman MG, Waid DM, Wagner DH. Th40 cells (CD4+CD40+ Tcells) drive a more severe form of Experimental Autoimmune Encephalomyelitis than conventional CD4 T cells. PLoS One. 2017; 12(2):e0172037.
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