 Interferon-gamma
"Interferon-gamma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.
| Descriptor ID |
D007371
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| MeSH Number(s) |
D12.644.276.374.440.893 D12.644.276.374.480.615.350 D12.776.467.374.440.893 D12.776.467.374.480.615.350 D23.529.374.440.893 D23.529.374.480.615.350
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| Concept/Terms |
Interferon-gamma- Interferon-gamma
- gamma-Interferon
- Interferon, Immune
- Immune Interferon
- Type II Interferon
- Interferon, Type II
- Interferon Type II
- Interferon, gamma
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Below are MeSH descriptors whose meaning is more general than "Interferon-gamma".
Below are MeSH descriptors whose meaning is more specific than "Interferon-gamma".
This graph shows the total number of publications written about "Interferon-gamma" by people in this website by year, and whether "Interferon-gamma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1991 | 1 | 1 | 2 | | 1992 | 2 | 4 | 6 | | 1993 | 3 | 4 | 7 | | 1994 | 1 | 8 | 9 | | 1995 | 3 | 4 | 7 | | 1996 | 3 | 9 | 12 | | 1997 | 1 | 2 | 3 | | 1998 | 7 | 12 | 19 | | 1999 | 1 | 7 | 8 | | 2000 | 8 | 8 | 16 | | 2001 | 7 | 16 | 23 | | 2002 | 9 | 12 | 21 | | 2003 | 13 | 16 | 29 | | 2004 | 6 | 12 | 18 | | 2005 | 7 | 17 | 24 | | 2006 | 7 | 12 | 19 | | 2007 | 11 | 18 | 29 | | 2008 | 5 | 24 | 29 | | 2009 | 10 | 11 | 21 | | 2010 | 9 | 17 | 26 | | 2011 | 6 | 19 | 25 | | 2012 | 4 | 17 | 21 | | 2013 | 8 | 13 | 21 | | 2014 | 4 | 16 | 20 | | 2015 | 4 | 17 | 21 | | 2016 | 6 | 11 | 17 | | 2017 | 1 | 10 | 11 | | 2018 | 3 | 8 | 11 | | 2019 | 8 | 6 | 14 | | 2020 | 2 | 3 | 5 |
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Below are the most recent publications written about "Interferon-gamma" by people in Profiles.
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Locatelli F, Jordan MB, Allen C, Cesaro S, Rizzari C, Rao A, Degar B, Garrington TP, Sevilla J, Putti MC, Fagioli F, Ahlmann M, Dapena Diaz JL, Henry M, De Benedetti F, Grom A, Lapeyre G, Jacqmin P, Ballabio M, de Min C. Emapalumab in Children with Primary Hemophagocytic Lymphohistiocytosis. N Engl J Med. 2020 05 07; 382(19):1811-1822.
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Leavitt C, Zakai NA, Auer P, Cushman M, Lange EM, Levitan EB, Olson N, Thornton TA, Tracy RP, Wilson JG, Lange LA, Reiner AP, Raffield LM. Interferon gamma-induced protein 10 (IP-10) and cardiovascular disease in African Americans. PLoS One. 2020; 15(4):e0231013.
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Smith C, Moraka NO, Ibrahim M, Moyo S, Mayondi G, Kammerer B, Leidner J, Gaseitsiwe S, Li S, Shapiro R, Lockman S, Weinberg A. Human Immunodeficiency Virus Exposure but Not Early Cytomegalovirus Infection Is Associated With Increased Hospitalization and Decreased Memory T-Cell Responses to Tetanus Vaccine. J Infect Dis. 2020 03 16; 221(7):1167-1175.
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Lupieri A, Smirnova NF, Solinhac R, Malet N, Benamar M, Saoudi A, Santos-Zas I, Zeboudj L, Ait-Oufella H, Hirsch E, Ohayon P, Lhermusier T, Carrié D, Arnal JF, Ramel D, Gayral S, Laffargue M. Smooth muscle cells-derived CXCL10 prevents endothelial healing through PI3K?-dependent T cells response. Cardiovasc Res. 2020 02 01; 116(2):438-449.
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Loh L, Gherardin NA, Sant S, Grzelak L, Crawford JC, Bird NL, Koay HF, van de Sandt CE, Moreira ML, Lappas M, Allen EK, Crowe J, Loudovaris T, Flanagan KL, Quinn KM, Rossjohn J, Thomas PG, Eckle SBG, McCluskey J, Godfrey DI, Kedzierska K. Human Mucosal-Associated Invariant T Cells in Older Individuals Display Expanded TCRaß Clonotypes with Potent Antimicrobial Responses. J Immunol. 2020 03 01; 204(5):1119-1133.
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Sirobhushanam S, Parsa N, Reed TJ, Berthier CC, Sarkar MK, Hile GA, Tsoi LC, Banfield J, Dobry C, Horswill AR, Gudjonsson JE, Kahlenberg JM. Staphylococcus aureus Colonization Is Increased on Lupus Skin Lesions and Is Promoted by IFN-Mediated Barrier Disruption. J Invest Dermatol. 2020 05; 140(5):1066-1074.e4.
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Walrath T, Malizia RA, Zhu X, Sharp SP, D'Souza SS, Lopez-Soler R, Parr B, Kartchner B, Lee EC, Stain SC, Iwakura Y, O'Connor W. IFN-? and IL-17A regulate intestinal crypt production of CXCL10 in the healthy and inflamed colon. Am J Physiol Gastrointest Liver Physiol. 2020 03 01; 318(3):G479-G489.
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Lewis CV, Vinh A, Diep H, Samuel CS, Drummond GR, Kemp-Harper BK. Distinct Redox Signalling following Macrophage Activation Influences Profibrotic Activity. J Immunol Res. 2019; 2019:1278301.
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Araya P, Waugh KA, Sullivan KD, Núñez NG, Roselli E, Smith KP, Granrath RE, Rachubinski AL, Enriquez Estrada B, Butcher ET, Minter R, Tuttle KD, Bruno TC, Maccioni M, Espinosa JM. Trisomy 21 dysregulates T cell lineages toward an autoimmunity-prone state associated with interferon hyperactivity. Proc Natl Acad Sci U S A. 2019 11 26; 116(48):24231-24241.
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Crisler WJ, Eshleman EM, Lenz LL. Ligand-induced IFNGR1 down-regulation calibrates myeloid cell IFN? responsiveness. Life Sci Alliance. 2019 10; 2(5).
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