An-Jey Su
Title | Asst Professor-Research |
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Institution | University of Colorado Denver - Anschutz Medical Campus |
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Department | SOM-SRG |
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Email |  |
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Biography Duquesne University, Pittsburgh, PA | PhD | 2016 | Molecular Biology | University of Pittsburgh, Pittsburgh, PA | BS (Hons) | 2001 | Neuroscience/History & Philosophy of Science |
2019 | Emerging Vision Scientist, Alliance for Eye and Vision Research |
Overview Dr. Su is the Laboratory Director for Dr. Kia Washington MD. He holds scientific oversight of ongoing translational projects, investigating whole eye transplantation (WET), peripheral nerve regeneration, and vascularized composite allotransplantation. Our overarching goal is to restore a patient’s vision following disease, ocular trauma and ischemic or degenerative damage by total human eye allotransplantation (THEA). Our group has developed the world’s first orthotopic vascularized whole eye transplant small animal model. The next phase of research will involve a comprehensive approach to addressing the challenges of whole eye transplantation.
Bibliographic
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Washington KM, Solari MG, Zonoun RR, Kwegyir-Afful EE, Su AA, Carvell GE, Lee WPA, Simons DJ. Cortical Reintegration After Facial Allotransplantation. J Neurophysiol. 2022 Dec 21. PMID: 36542405.
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Komatsu C, van der Merwe Y, He L, Kasi A, Sims JR, Miller MR, Rosner IA, Khatter NJ, Su AA, Schuman JS, Washington KM, Chan KC. In vivo MRI evaluation of anterograde manganese transport along the visual pathway following whole eye transplantation. J Neurosci Methods. 2022 04 15; 372:109534. PMID: 35202613.
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Feng H, Lopez GY, Kim CK, Alvarez A, Duncan CG, Nishikawa R, Nagane M, Su AJ, Auron PE, Hedberg ML, Wang L, Raizer JJ, Kessler JA, Parsa AT, Gao WQ, Kim SH, Minata M, Nakano I, Grandis JR, McLendon RE, Bigner DD, Lin HK, Furnari FB, Cavenee WK, Hu B, Yan H, Cheng SY. EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis. J Clin Invest. 2014 Sep; 124(9):3741-56. PMID: 25061874.
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Chou WL, Galmozzi A, Partida D, Kwan K, Yeung H, Su AI, Saez E. Identification of regulatory elements that control PPAR? expression in adipocyte progenitors. PLoS One. 2013; 8(8):e72511. PMID: 24009687.
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Adamik J, Wang KZ, Unlu S, Su AJ, Tannahill GM, Galson DL, O'Neill LA, Auron PE. Distinct mechanisms for induction and tolerance regulate the immediate early genes encoding interleukin 1ß and tumor necrosis factor a. PLoS One. 2013; 8(8):e70622. PMID: 23936458.
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Shoulders MD, Ryno LM, Genereux JC, Moresco JJ, Tu PG, Wu C, Yates JR, Su AI, Kelly JW, Wiseman RL. Stress-independent activation of XBP1s and/or ATF6 reveals three functionally diverse ER proteostasis environments. Cell Rep. 2013 Apr 25; 3(4):1279-92. PMID: 23583182.
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Miller E, Yang J, DeRan M, Wu C, Su AI, Bonamy GM, Liu J, Peters EC, Wu X. Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP. Chem Biol. 2012 Aug 24; 19(8):955-62. PMID: 22884261.
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Geng X, Li L, Bottino R, Balamurugan AN, Bertera S, Densmore E, Su A, Chang Y, Trucco M, Drain P. Antidiabetic sulfonylurea stimulates insulin secretion independently of plasma membrane KATP channels. Am J Physiol Endocrinol Metab. 2007 Jul; 293(1):E293-301. PMID: 17405830.
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Melnick JS, Janes J, Kim S, Chang JY, Sipes DG, Gunderson D, Jarnes L, Matzen JT, Garcia ME, Hood TL, Beigi R, Xia G, Harig RA, Asatryan H, Yan SF, Zhou Y, Gu XJ, Saadat A, Zhou V, King FJ, Shaw CM, Su AI, Downs R, Gray NS, Schultz PG, Warmuth M, Caldwell JS. An efficient rapid system for profiling the cellular activities of molecular libraries. Proc Natl Acad Sci U S A. 2006 Feb 28; 103(9):3153-8. PMID: 16492761.
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Li L, Geng X, Yonkunas M, Su A, Densmore E, Tang P, Drain P. Ligand-dependent linkage of the ATP site to inhibition gate closure in the KATP channel. J Gen Physiol. 2005 Sep; 126(3):285-99. PMID: 16129775.
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Conkright MD, Guzmán E, Flechner L, Su AI, Hogenesch JB, Montminy M. Genome-wide analysis of CREB target genes reveals a core promoter requirement for cAMP responsiveness. Mol Cell. 2003 Apr; 11(4):1101-8. PMID: 12718894.
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Supekova L, Pezacki JP, Su AI, Loweth CJ, Riedl R, Geierstanger B, Schultz PG, Wemmer DE. Genomic effects of polyamide/DNA interactions on mRNA expression. Chem Biol. 2002 Jul; 9(7):821-7. PMID: 12144926.
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Panda S, Antoch MP, Miller BH, Su AI, Schook AB, Straume M, Schultz PG, Kay SA, Takahashi JS, Hogenesch JB. Coordinated transcription of key pathways in the mouse by the circadian clock. Cell. 2002 May 03; 109(3):307-20. PMID: 12015981.
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Chang YT, Wignall SM, Rosania GR, Gray NS, Hanson SR, Su AI, Merlie J, Moon HS, Sangankar SB, Perez O, Heald R, Schultz PG. Synthesis and biological evaluation of myoseverin derivatives: microtubule assembly inhibitors. J Med Chem. 2001 Dec 20; 44(26):4497-500. PMID: 11741468.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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Year | Publications |
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2001 | 1 | 2002 | 2 | 2003 | 1 | 2005 | 1 | 2006 | 1 | 2007 | 1 | 2012 | 1 | 2013 | 3 | 2014 | 1 | 2022 | 2 |
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