 NF-kappa B
"NF-kappa B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Ubiquitous, inducible, nuclear transcriptional activator that binds to enhancer elements in many different cell types and is activated by pathogenic stimuli. The NF-kappa B complex is a heterodimer composed of two DNA-binding subunits: NF-kappa B1 and relA.
| Descriptor ID |
D016328
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| MeSH Number(s) |
D12.776.260.600 D12.776.660.600 D12.776.930.600
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| Concept/Terms |
NF-kappa B- NF-kappa B
- kappa B Enhancer Binding Protein
- NF-kappaB
- NF kappaB
- Transcription Factor NF-kB
- Factor NF-kB, Transcription
- NF-kB, Transcription Factor
- Transcription Factor NF kB
- NF-kB
- NF kB
- Immunoglobulin Enhancer-Binding Protein
- Enhancer-Binding Protein, Immunoglobulin
- Immunoglobulin Enhancer Binding Protein
- Nuclear Factor kappa B
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Below are MeSH descriptors whose meaning is more general than "NF-kappa B".
Below are MeSH descriptors whose meaning is more specific than "NF-kappa B".
This graph shows the total number of publications written about "NF-kappa B" by people in this website by year, and whether "NF-kappa B" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 1 | 0 | 1 | | 1993 | 2 | 0 | 2 | | 1995 | 4 | 1 | 5 | | 1996 | 4 | 2 | 6 | | 1997 | 4 | 3 | 7 | | 1998 | 3 | 1 | 4 | | 1999 | 4 | 5 | 9 | | 2000 | 9 | 5 | 14 | | 2001 | 6 | 8 | 14 | | 2002 | 8 | 16 | 24 | | 2003 | 14 | 15 | 29 | | 2004 | 13 | 6 | 19 | | 2005 | 9 | 15 | 24 | | 2006 | 7 | 11 | 18 | | 2007 | 6 | 20 | 26 | | 2008 | 6 | 18 | 24 | | 2009 | 10 | 12 | 22 | | 2010 | 4 | 15 | 19 | | 2011 | 5 | 17 | 22 | | 2012 | 6 | 16 | 22 | | 2013 | 7 | 16 | 23 | | 2014 | 11 | 14 | 25 | | 2015 | 6 | 7 | 13 | | 2016 | 1 | 10 | 11 | | 2017 | 3 | 9 | 12 | | 2018 | 5 | 2 | 7 | | 2019 | 3 | 10 | 13 | | 2020 | 4 | 3 | 7 |
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Below are the most recent publications written about "NF-kappa B" by people in Profiles.
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Gergen AK, Kohtz PD, Halpern AL, Li A, Meng X, Reece TB, Fullerton DA, Weyant MJ. Activation of Toll-Like Receptor 2 Promotes Proliferation of Human Lung Adenocarcinoma Cells. Anticancer Res. 2020 Oct; 40(10):5361-5369.
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Goto RN, Sobral LM, Stringhetta-Padovani K, Garcia CB, da Silva G, Vitek MP, Leopoldino AM. Synergic effect of OP449 and FTY720 on oral squamous cell carcinoma. Eur J Pharmacol. 2020 Sep 05; 882:173268.
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Wright CJ, Cari EL, Sandoval J, Bales E, Sam PK, Zarate MA, Polotsky AJ, Kallen AN, Johnson J. Control of Murine Primordial Follicle Growth Activation by I?B/NF?B Signaling. Reprod Sci. 2020 11; 27(11):2063-2074.
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Lee FF, Davidson K, Harris C, McClendon J, Janssen WJ, Alper S. NF-?B mediates lipopolysaccharide-induced alternative pre-mRNA splicing of MyD88 in mouse macrophages. J Biol Chem. 2020 05 01; 295(18):6236-6248.
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The E, Yao Q, Zhang P, Zhai Y, Ao L, Fullerton DA, Meng X. Mechanistic Roles of Matrilin-2 and Klotho in Modulating the Inflammatory Activity of Human Aortic Valve Cells. Cells. 2020 02 07; 9(2).
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Harrold AP, Cleary MM, Bharathy N, Lathara M, Berlow NE, Foreman NK, Donson AM, Amani V, Zuercher WJ, Keller C. In vitro benchmarking of NF-?B inhibitors. Eur J Pharmacol. 2020 Apr 15; 873:172981.
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Mendez JM, Keestra-Gounder AM. NF-?B-dependent Luciferase Activation and Quantification of Gene Expression in Salmonella Infected Tissue Culture Cells. J Vis Exp. 2020 01 12; (155).
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Yang C, McDermot DS, Pasricha S, Brown AS, Bedoui S, Lenz LL, van Driel IR, Hartland EL. IFN? receptor down-regulation facilitates Legionella survival in alveolar macrophages. J Leukoc Biol. 2020 02; 107(2):273-284.
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Wyatt GL, Crump LS, Young CM, Wessells VM, McQueen CM, Wall SW, Gustafson TL, Fan YY, Chapkin RS, Porter WW, Lyons TR. Cross-talk between SIM2s and NF?B regulates cyclooxygenase 2 expression in breast cancer. Breast Cancer Res. 2019 11 29; 21(1):131.
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Jarrett MJ, Yao Q, Venardos N, Weyant MJ, Reece TB, Meng X, Fullerton DA. Simvastatin down-regulates osteogenic response in cultured human aortic valve interstitial cells. J Thorac Cardiovasc Surg. 2021 04; 161(4):e261-e271.
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