 NF-kappa B
"NF-kappa B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Ubiquitous, inducible, nuclear transcriptional activator that binds to enhancer elements in many different cell types and is activated by pathogenic stimuli. The NF-kappa B complex is a heterodimer composed of two DNA-binding subunits: NF-kappa B1 and relA.
| Descriptor ID |
D016328
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| MeSH Number(s) |
D12.776.260.600 D12.776.660.600 D12.776.930.600
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| Concept/Terms |
NF-kappa B- NF-kappa B
- kappa B Enhancer Binding Protein
- NF-kappaB
- NF kappaB
- Transcription Factor NF-kB
- Factor NF-kB, Transcription
- NF-kB, Transcription Factor
- Transcription Factor NF kB
- NF-kB
- NF kB
- Immunoglobulin Enhancer-Binding Protein
- Enhancer-Binding Protein, Immunoglobulin
- Immunoglobulin Enhancer Binding Protein
- Nuclear Factor kappa B
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Below are MeSH descriptors whose meaning is more general than "NF-kappa B".
Below are MeSH descriptors whose meaning is more specific than "NF-kappa B".
This graph shows the total number of publications written about "NF-kappa B" by people in this website by year, and whether "NF-kappa B" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 1 | 0 | 1 | | 1993 | 2 | 0 | 2 | | 1995 | 4 | 1 | 5 | | 1996 | 4 | 2 | 6 | | 1997 | 4 | 3 | 7 | | 1998 | 3 | 1 | 4 | | 1999 | 4 | 5 | 9 | | 2000 | 9 | 5 | 14 | | 2001 | 5 | 8 | 13 | | 2002 | 8 | 16 | 24 | | 2003 | 13 | 15 | 28 | | 2004 | 13 | 6 | 19 | | 2005 | 9 | 16 | 25 | | 2006 | 7 | 11 | 18 | | 2007 | 6 | 19 | 25 | | 2008 | 6 | 18 | 24 | | 2009 | 10 | 12 | 22 | | 2010 | 4 | 15 | 19 | | 2011 | 5 | 16 | 21 | | 2012 | 6 | 16 | 22 | | 2013 | 7 | 16 | 23 | | 2014 | 11 | 15 | 26 | | 2015 | 6 | 7 | 13 | | 2016 | 1 | 11 | 12 | | 2017 | 3 | 9 | 12 | | 2018 | 5 | 2 | 7 | | 2019 | 3 | 10 | 13 | | 2020 | 6 | 4 | 10 | | 2021 | 4 | 4 | 8 |
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Below are the most recent publications written about "NF-kappa B" by people in Profiles.
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Gupta A, Sasse SK, Gruca MA, Sanford L, Dowell RD, Gerber AN. Deconvolution of multiplexed transcriptional responses to wood smoke particles defines rapid aryl hydrocarbon receptor signaling dynamics. J Biol Chem. 2021 10; 297(4):101147.
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Zarate MA, De Dios RK, Balasubramaniyan D, Zheng L, Sherlock LG, Rozance PJ, Wright CJ. The Acute Hepatic NF-?B-Mediated Proinflammatory Response to Endotoxemia Is Attenuated in Intrauterine Growth-Restricted Newborn Mice. Front Immunol. 2021; 12:706774.
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Gallagher MP, Conley JM, Vangala P, Garber M, Reboldi A, Berg LJ. Hierarchy of signaling thresholds downstream of the T cell receptor and the Tec kinase ITK. Proc Natl Acad Sci U S A. 2021 08 31; 118(35).
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Clement CC, D'Alessandro A, Thangaswamy S, Chalmers S, Furtado R, Spada S, Mondanelli G, Ianni F, Gehrke S, Gargaro M, Manni G, Cara LCL, Runge P, Tsai WL, Karaman S, Arasa J, Fernandez-Rodriguez R, Beck A, Macchiarulo A, Gadina M, Halin C, Fallarino F, Skobe M, Veldhoen M, Moretti S, Formenti S, Demaria S, Soni RK, Galarini R, Sardella R, Lauvau G, Putterman C, Alitalo K, Grohmann U, Santambrogio L. 3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine. Nat Commun. 2021 07 21; 12(1):4447.
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Penthala NR, Balasubramaniam M, Dachavaram SS, Morris EJ, Bhat-Nakshatri P, Ponder J, Jordan CT, Nakshatri H, Crooks PA. Antitumor properties of novel sesquiterpene lactone analogs as NF?B inhibitors that bind to the IKKß ubiquitin-like domain (ULD). Eur J Med Chem. 2021 Nov 15; 224:113675.
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Wright CJ, McKenna S, De Dios R, Boehmer BH, Nguyen L, Ghosh S, Sandoval J, Rozance PJ. Lower threshold to NF?B activity sensitizes murine ß-cells to streptozotocin. J Endocrinol. 2021 05 06; 249(3):163-175.
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Gerber AN, Newton R, Sasse SK. Repression of transcription by the glucocorticoid receptor: A parsimonious model for the genomics era. J Biol Chem. 2021 Jan-Jun; 296:100687.
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Li S, Jiang L, Beckmann K, Højen JF, Pessara U, Powers NE, de Graaf DM, Azam T, Lindenberger J, Eisenmesser EZ, Fischer S, Dinarello CA. A novel anti-human IL-1R7 antibody reduces IL-18-mediated inflammatory signaling. J Biol Chem. 2021 Jan-Jun; 296:100630.
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Zou M, Zhang X, Jiang D, Zhao Y, Wu T, Gong Q, Su H, Wu D, Moreland L, Li G. Transcriptional Regulation of CD40 Expression by 4 Ribosomal Proteins via a Functional SNP on a Disease-Associated CD40 Locus. Genes (Basel). 2020 12 21; 11(12).
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Gergen AK, Kohtz PD, Halpern AL, Li A, Meng X, Reece TB, Fullerton DA, Weyant MJ. Activation of Toll-Like Receptor 2 Promotes Proliferation of Human Lung Adenocarcinoma Cells. Anticancer Res. 2020 Oct; 40(10):5361-5369.
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