Early Growth Response Protein 2
"Early Growth Response Protein 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An early growth response transcription factor that controls the formation of the MYELIN SHEATH around peripheral AXONS by SCHWANN CELLS. Mutations in EGR2 transcription factor have been associated with HEREDITARY MOTOR AND SENSORY NEUROPATHIES such as CHARCOT-MARIE-TOOTH DISEASE.
Descriptor ID |
D051767
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MeSH Number(s) |
D12.776.260.158.750 D12.776.460.525.750 D12.776.930.213.750
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Concept/Terms |
Early Growth Response Protein 2- Early Growth Response Protein 2
- Krox-20 Transcription Factor
- Krox 20 Transcription Factor
- Transcription Factor, Krox-20
- EGR2 Transcription Factor
- Transcription Factor, EGR2
- Krox20 Protein
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Below are MeSH descriptors whose meaning is more general than "Early Growth Response Protein 2".
Below are MeSH descriptors whose meaning is more specific than "Early Growth Response Protein 2".
This graph shows the total number of publications written about "Early Growth Response Protein 2" by people in this website by year, and whether "Early Growth Response Protein 2" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2013 | 0 | 1 | 1 | 2018 | 0 | 1 | 1 | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Early Growth Response Protein 2" by people in Profiles.
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Kamran M, Liang J, Liu B, Li Y, Gao J, Keating A, Mohamed F, Dai S, Reinhardt R, Jiong Y, Wu Z, Huang H. The Clusters of Transcription Factors NFATC2, STAT5, GATA2, AP1, RUNX1 and EGR2 Binding Sites at the Induced Il13 Enhancers Mediate Il13 Gene Transcription in Response to Antigenic Stimulation. J Immunol. 2020 12 15; 205(12):3311-3318.
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Tuttle KD, Krovi SH, Zhang J, Bedel R, Harmacek L, Peterson LK, Dragone LL, Lefferts A, Halluszczak C, Riemondy K, Hesselberth JR, Rao A, O'Connor BP, Marrack P, Scott-Browne J, Gapin L. TCR signal strength controls thymic differentiation of iNKT cell subsets. Nat Commun. 2018 07 09; 9(1):2650.
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Bedel R, Berry R, Mallevaey T, Matsuda JL, Zhang J, Godfrey DI, Rossjohn J, Kappler JW, Marrack P, Gapin L. Effective functional maturation of invariant natural killer T cells is constrained by negative selection and T-cell antigen receptor affinity. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):E119-28.
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