Regulon
"Regulon" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
In eukaryotes, a genetic unit consisting of a noncontiguous group of genes under the control of a single regulator gene. In bacteria, regulons are global regulatory systems involved in the interplay of pleiotropic regulatory domains and consist of several OPERONS.
Descriptor ID |
D018085
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MeSH Number(s) |
G05.360.340.024.742
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Regulon".
Below are MeSH descriptors whose meaning is more specific than "Regulon".
This graph shows the total number of publications written about "Regulon" by people in this website by year, and whether "Regulon" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2001 | 0 | 1 | 1 | 2002 | 0 | 1 | 1 | 2004 | 1 | 0 | 1 | 2006 | 0 | 1 | 1 | 2007 | 1 | 1 | 2 | 2008 | 0 | 1 | 1 | 2009 | 2 | 1 | 3 | 2010 | 0 | 2 | 2 | 2011 | 3 | 1 | 4 | 2013 | 0 | 1 | 1 | 2014 | 1 | 0 | 1 | 2015 | 2 | 1 | 3 | 2016 | 0 | 1 | 1 | 2017 | 2 | 0 | 2 | 2018 | 1 | 2 | 3 | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Regulon" by people in Profiles.
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Flores-Valdez MA, Aceves-Sánchez MJ, Peterson EJR, Baliga N, Bravo-Madrigal J, De la Cruz-Villegas MÁ, Ares MA, Born S, Voskuil M, Pérez-Padilla NA, Burciaga-Flores M, Camacho-Villegas TA, Espinoza-Jorge MG. Transcriptional portrait of M. bovis BCG during biofilm production shows genes differentially expressed during intercellular aggregation and substrate attachment. Sci Rep. 2020 07 28; 10(1):12578.
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Tapscott T, Kim JS, Crawford MA, Fitzsimmons L, Liu L, Jones-Carson J, Vázquez-Torres A. Guanosine tetraphosphate relieves the negative regulation of Salmonella pathogenicity island-2 gene transcription exerted by the AT-rich ssrA discriminator region. Sci Rep. 2018 06 21; 8(1):9465.
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Sporer AJ, Beierschmitt C, Bendebury A, Zink KE, Price-Whelan A, Buzzeo MC, Sanchez LM, Dietrich LEP. Pseudomonas aeruginosa PumA acts on an endogenous phenazine to promote self-resistance. Microbiology (Reading). 2018 05; 164(5):790-800.
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Demmig-Adams B, Stewart JJ, Baker CR, Adams WW. Optimization of Photosynthetic Productivity in Contrasting Environments by Regulons Controlling Plant Form and Function. Int J Mol Sci. 2018 Mar 15; 19(3).
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Reichlen MJ, Leistikow RL, Scobey MS, Born SEM, Voskuil MI. Anaerobic Mycobacterium tuberculosis Cell Death Stems from Intracellular Acidification Mitigated by the DosR Regulon. J Bacteriol. 2017 12 01; 199(23).
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Kimuda SG, Nalwoga A, Levin J, Franken KL, Ottenhoff TH, Elliott AM, Cose S, Andia-Biraro I. Humoral Responses to Rv1733c, Rv0081, Rv1735c, and Rv1737c DosR Regulon-Encoded Proteins of Mycobacterium tuberculosis in Individuals with Latent Tuberculosis Infection. J Immunol Res. 2017; 2017:1593143.
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Walter ND, de Jong BC, Garcia BJ, Dolganov GM, Worodria W, Byanyima P, Musisi E, Huang L, Chan ED, Van TT, Antonio M, Ayorinde A, Kato-Maeda M, Nahid P, Leung AM, Yen A, Fingerlin TE, Kechris K, Strong M, Voskuil MI, Davis JL, Schoolnik GK. Adaptation of Mycobacterium tuberculosis to Impaired Host Immunity in HIV-Infected Patients. J Infect Dis. 2016 10 15; 214(8):1205-11.
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An X, Zhang C, Sclafani RA, Seligman P, Huang M. The late-annotated small ORF LSO1 is a target gene of the iron regulon of Saccharomyces cerevisiae. Microbiologyopen. 2015 Dec; 4(6):941-51.
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Drecktrah D, Lybecker M, Popitsch N, Rescheneder P, Hall LS, Samuels DS. The Borrelia burgdorferi RelA/SpoT Homolog and Stringent Response Regulate Survival in the Tick Vector and Global Gene Expression during Starvation. PLoS Pathog. 2015 Sep; 11(9):e1005160.
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Voskuil MI, Schlesinger LS. Toward Resolving the Paradox of the Critical Role of the DosR Regulon in Mycobacterium tuberculosis Persistence and Active Disease. Am J Respir Crit Care Med. 2015 May 15; 191(10):1103-5.
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