 Virulence
"Virulence" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.
| Descriptor ID |
D014774
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| MeSH Number(s) |
G06.930
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Virulence".
Below are MeSH descriptors whose meaning is more specific than "Virulence".
This graph shows the total number of publications written about "Virulence" by people in this website by year, and whether "Virulence" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 0 | 2 | 2 | | 1993 | 0 | 1 | 1 | | 1994 | 0 | 2 | 2 | | 1995 | 0 | 2 | 2 | | 1996 | 0 | 2 | 2 | | 1997 | 0 | 1 | 1 | | 1998 | 0 | 3 | 3 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2001 | 0 | 5 | 5 | | 2002 | 0 | 6 | 6 | | 2003 | 1 | 5 | 6 | | 2004 | 0 | 5 | 5 | | 2005 | 0 | 1 | 1 | | 2006 | 0 | 3 | 3 | | 2007 | 1 | 3 | 4 | | 2008 | 0 | 5 | 5 | | 2009 | 0 | 2 | 2 | | 2010 | 0 | 9 | 9 | | 2011 | 0 | 6 | 6 | | 2012 | 1 | 5 | 6 | | 2013 | 0 | 12 | 12 | | 2014 | 0 | 11 | 11 | | 2015 | 0 | 8 | 8 | | 2016 | 2 | 3 | 5 | | 2017 | 0 | 6 | 6 | | 2018 | 1 | 6 | 7 | | 2019 | 1 | 9 | 10 | | 2020 | 0 | 11 | 11 | | 2021 | 2 | 4 | 6 | | 2022 | 0 | 4 | 4 |
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Below are the most recent publications written about "Virulence" by people in Profiles.
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Kwiecinski JM, Jelani DA, Fuentes EJ, Horswill AR. Therapeutic Inhibition of Staphylococcus aureus ArlRS Two-Component Regulatory System Blocks Virulence. Antimicrob Agents Chemother. 2022 07 19; 66(7):e0018722.
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Wittekind MA, Frey A, Bonsall AE, Briaud P, Keogh RA, Wiemels RE, Shaw LN, Carroll RK. The novel protein ScrA acts through the SaeRS two-component system to regulate virulence gene expression in Staphylococcus aureus. Mol Microbiol. 2022 05; 117(5):1196-1212.
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Manzer HS, Villarreal RI, Doran KS. Targeting the BspC-vimentin interaction to develop anti-virulence therapies during Group B streptococcal meningitis. PLoS Pathog. 2022 03; 18(3):e1010397.
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Vang CK, Dawrs SN, Oberlag NM, Gilmore AE, Hasan NA, Honda JR. Comparative survival of environmental and clinical Mycobacterium abscessus isolates in a variety of diverse host cells. J Appl Microbiol. 2022 Apr; 132(4):3302-3314.
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Spencer BL, Tak U, Mendonça JC, Nagao PE, Niederweis M, Doran KS. A type VII secretion system in Group B Streptococcus mediates cytotoxicity and virulence. PLoS Pathog. 2021 12; 17(12):e1010121.
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Brissac T, MartÃnez E, Kruckow KL, Riegler AN, Ganaie F, Im H, Bakshi S, Arroyo-Diaz NM, Spencer BL, Saad JS, Nahm MH, Orihuela CJ. Capsule Promotes Intracellular Survival and Vascular Endothelial Cell Translocation during Invasive Pneumococcal Disease. mBio. 2021 10 26; 12(5):e0251621.
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Russo BC, Duncan-Lowey JK, Chen P, Goldberg MB. The type 3 secretion system requires actin polymerization to open translocon pores. PLoS Pathog. 2021 09; 17(9):e1009932.
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Kwiecinski JM, Kratofil RM, Parlet CP, Surewaard BGJ, Kubes P, Horswill AR. Staphylococcus aureus uses the ArlRS and MgrA cascade to regulate immune evasion during skin infection. Cell Rep. 2021 07 27; 36(4):109462.
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Haist KC, Carpentier KS, Davenport BJ, Morrison TE. Plasmacytoid Dendritic Cells Mediate Control of Ross River Virus Infection via a Type I Interferon-Dependent, MAVS-Independent Mechanism. J Virol. 2021 02 24; 95(6).
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Grosse-Siestrup BT, Gupta T, Helms S, Tucker SL, Voskuil MI, Quinn FD, Karls RK. A Role for Mycobacterium tuberculosis Sigma Factor C in Copper Nutritional Immunity. Int J Mol Sci. 2021 Feb 20; 22(4).
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