 Indomethacin
"Indomethacin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A non-steroidal anti-inflammatory agent (NSAID) that inhibits the enzyme cyclooxygenase necessary for the formation of prostaglandins and other autacoids. It also inhibits the motility of polymorphonuclear leukocytes.
| Descriptor ID |
D007213
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| MeSH Number(s) |
D03.633.100.473.420
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Indomethacin".
Below are MeSH descriptors whose meaning is more specific than "Indomethacin".
This graph shows the total number of publications written about "Indomethacin" by people in this website by year, and whether "Indomethacin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 0 | 3 | 3 | | 1992 | 1 | 1 | 2 | | 1993 | 1 | 0 | 1 | | 1996 | 0 | 2 | 2 | | 1997 | 0 | 1 | 1 | | 2000 | 0 | 2 | 2 | | 2002 | 1 | 2 | 3 | | 2003 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 | | 2006 | 3 | 2 | 5 | | 2007 | 1 | 1 | 2 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 1 | 2 | | 2013 | 1 | 0 | 1 | | 2015 | 1 | 1 | 2 | | 2016 | 1 | 0 | 1 | | 2018 | 1 | 1 | 2 |
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Below are the most recent publications written about "Indomethacin" by people in Profiles.
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Howley LW, Chatterjee D, Patel SS, Cuneo BF, Crombleholme TM, Behrendt N, Zaretsky MV, Marwan AI, Zuk J, Galan HL, Wood C. Indomethacin Dosing and Constriction of the Ductus Arteriosus During Open Fetal Surgery for Myelomeningocele Repair. Fetal Diagn Ther. 2019; 45(5):339-344.
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Stremming JE, Wright CJ, Brown LD. Is paracetamol as effective as indomethacin or ibuprofen in closing a hemodynamically significant patent ductus arteriosus in preterm infants? Acta Paediatr. 2018 10; 107(10):1836.
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Burgess KR, Lucas SJE, Burgess KME, Sprecher KE, Donnelly J, Basnet AS, Tymko MM, Day T, Smith K, Lewis N, Ainslie PN. Increasing cerebral blood flow reduces the severity of central sleep apnea at high altitude. J Appl Physiol (1985). 2018 05 01; 124(5):1341-1348.
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Elmunzer BJ, Serrano J, Chak A, Edmundowicz SA, Papachristou GI, Scheiman JM, Singh VK, Varadarajulu S, Vargo JJ, Willingham FF, Baron TH, Coté GA, Romagnuolo J, Wood-Williams A, Depue EK, Spitzer RL, Spino C, Foster LD, Durkalski V. Rectal indomethacin alone versus indomethacin and prophylactic pancreatic stent placement for preventing pancreatitis after ERCP: study protocol for a randomized controlled trial. Trials. 2016 03 03; 17(1):120.
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Faucett AM, Metz TD, DeWitt PE, Gibbs RS. Effect of obesity on neonatal outcomes in pregnancies with preterm premature rupture of membranes. Am J Obstet Gynecol. 2016 Feb; 214(2):287.e1-287.e5.
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Howley L, Wood C, Patel SS, Zaretsky MV, Crombleholme T, Cuneo B. Flow patterns in the ductus arteriosus during open fetal myelomeningocele repair. Prenat Diagn. 2015 Jun; 35(6):564-70.
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Sultana F, Rasool M. A novel therapeutic approach targeting rheumatoid arthritis by combined administration of morin, a dietary flavanol and non-steroidal anti-inflammatory drug indomethacin with reference to pro-inflammatory cytokines, inflammatory enzymes, RANKL and transcription factors. Chem Biol Interact. 2015 Mar 25; 230:58-70.
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Altman R, Daniels S, Young CL. Indomethacin submicron particle capsules provide effective pain relief in patients with acute pain: a phase 3 study. Phys Sportsmed. 2013 Nov; 41(4):7-15.
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Manvelian G, Daniels S, Altman R. A phase I study evaluating the pharmacokinetic profile of a novel, proprietary, nano-formulated, lower-dose oral indomethacin. Postgrad Med. 2012 Jul; 124(4):197-205.
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Eckman DM, Gupta R, Rosenfeld CR, Morgan TM, Charles SM, Mertz H, Moore LG. Pregnancy increases myometrial artery myogenic tone via NOS- or COX-independent mechanisms. . 2012 Aug 15; 303(4):R368-75.
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