 Enzyme-Linked Immunosorbent Assay
"Enzyme-Linked Immunosorbent Assay" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.
| Descriptor ID |
D004797
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| MeSH Number(s) |
E05.478.566.350.170 E05.478.566.380.360 E05.478.583.400.170 E05.601.495.350.170 E05.601.495.380.360
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| Concept/Terms |
Enzyme-Linked Immunosorbent Assay- Enzyme-Linked Immunosorbent Assay
- Assay, Enzyme-Linked Immunosorbent
- Assays, Enzyme-Linked Immunosorbent
- Enzyme Linked Immunosorbent Assay
- Enzyme-Linked Immunosorbent Assays
- Immunosorbent Assay, Enzyme-Linked
- Immunosorbent Assays, Enzyme-Linked
- ELISA
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Below are MeSH descriptors whose meaning is more general than "Enzyme-Linked Immunosorbent Assay".
Below are MeSH descriptors whose meaning is more specific than "Enzyme-Linked Immunosorbent Assay".
This graph shows the total number of publications written about "Enzyme-Linked Immunosorbent Assay" by people in this website by year, and whether "Enzyme-Linked Immunosorbent Assay" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1982 | 0 | 1 | 1 | | 1983 | 0 | 1 | 1 | | 1984 | 0 | 2 | 2 | | 1985 | 2 | 4 | 6 | | 1986 | 0 | 4 | 4 | | 1987 | 0 | 3 | 3 | | 1988 | 0 | 5 | 5 | | 1989 | 0 | 8 | 8 | | 1990 | 1 | 3 | 4 | | 1991 | 0 | 6 | 6 | | 1992 | 3 | 7 | 10 | | 1993 | 0 | 5 | 5 | | 1994 | 0 | 10 | 10 | | 1995 | 0 | 4 | 4 | | 1996 | 2 | 8 | 10 | | 1997 | 0 | 7 | 7 | | 1998 | 0 | 9 | 9 | | 1999 | 1 | 13 | 14 | | 2000 | 0 | 8 | 8 | | 2001 | 2 | 9 | 11 | | 2002 | 2 | 14 | 16 | | 2003 | 1 | 21 | 22 | | 2004 | 3 | 20 | 23 | | 2005 | 2 | 22 | 24 | | 2006 | 0 | 24 | 24 | | 2007 | 1 | 19 | 20 | | 2008 | 0 | 27 | 27 | | 2009 | 2 | 40 | 42 | | 2010 | 1 | 40 | 41 | | 2011 | 1 | 49 | 50 | | 2012 | 1 | 31 | 32 | | 2013 | 2 | 33 | 35 | | 2014 | 3 | 29 | 32 | | 2015 | 0 | 26 | 26 | | 2016 | 2 | 18 | 20 | | 2017 | 1 | 12 | 13 |
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Below are the most recent publications written about "Enzyme-Linked Immunosorbent Assay" by people in Profiles.
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Alhalwani AY, Repine JE, Knowles MK, Huffman JA. Development of a sandwich ELISA with potential for selective quantification of human lactoferrin protein nitrated through disease or environmental exposure. Anal Bioanal Chem. 2018 Feb; 410(4):1389-1396.
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Moore HB, Moore EE, Huebner BR, Dzieciatkowska M, Stettler GR, Nunns GR, Lawson PJ, Ghasabyan A, Chandler J, Banerjee A, Silliman C, Sauaia A, Hansen KC. Fibrinolysis shutdown is associated with a fivefold increase in mortality in trauma patients lacking hypersensitivity to tissue plasminogen activator. J Trauma Acute Care Surg. 2017 Dec; 83(6):1014-1022.
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Casaletto KB, Elahi FM, Bettcher BM, Neuhaus J, Bendlin BB, Asthana S, Johnson SC, Yaffe K, Carlsson C, Blennow K, Zetterberg H, Kramer JH. Neurogranin, a synaptic protein, is associated with memory independent of Alzheimer biomarkers. Neurology. 2017 Oct 24; 89(17):1782-1788.
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Sun B, Dalvi P, Abadjian L, Tang N, Pulliam L. Blood neuron-derived exosomes as biomarkers of cognitive impairment in HIV. AIDS. 2017 09 10; 31(14):F9-F17.
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Levin MJ, Buchwald UK, Gardner J, Martin J, Stek JE, Brown E, Popmihajlov Z. Immunogenicity and safety of zoster vaccine live administered with quadrivalent influenza virus vaccine. Vaccine. 2018 01 02; 36(1):179-185.
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Lee CC, Young KA, Norris JM, Rotter JI, Liu Y, Lorenzo C, Wagenknecht LE, Cole DE, Haffner SM, Chen YI, Hanley AJ. Association of Directly Measured Plasma Free 25(OH)D With Insulin Sensitivity and Secretion: The IRAS Family Study. J Clin Endocrinol Metab. 2017 08 01; 102(8):2781-2788.
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Munks MW, Montoya AM, Pywell CM, Talmage G, Forssen A, Campbell TL, Dodge DD, Kappler JW, Marrack P. The domestic cat antibody response to feline herpesvirus-1 increases with age. Vet Immunol Immunopathol. 2017 Jun; 188:65-70.
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Demoruelle MK, Harrall KK, Ho L, Purmalek MM, Seto NL, Rothfuss HM, Weisman MH, Solomon JJ, Fischer A, Okamoto Y, Kelmenson LB, Parish MC, Feser M, Fleischer C, Anderson C, Mahler M, Norris JM, Kaplan MJ, Cherrington BD, Holers VM, Deane KD. Anti-Citrullinated Protein Antibodies Are Associated With Neutrophil Extracellular Traps in the Sputum in Relatives of Rheumatoid Arthritis Patients. Arthritis Rheumatol. 2017 06; 69(6):1165-1175.
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Bergmark BA, Cannon CP, White WB, Jarolim P, Liu Y, Bonaca MP, Zannad F, Morrow DA. Baseline adiponectin concentration and clinical outcomes among patients with diabetes and recent acute coronary syndrome in the EXAMINE trial. Diabetes Obes Metab. 2017 07; 19(7):962-969.
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Hui H, Zhai Y, Ao L, Cleveland JC, Liu H, Fullerton DA, Meng X. Klotho suppresses the inflammatory responses and ameliorates cardiac dysfunction in aging endotoxemic mice. Oncotarget. 2017 Feb 28; 8(9):15663-15676.
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