 Enzyme-Linked Immunosorbent Assay
"Enzyme-Linked Immunosorbent Assay" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.
| Descriptor ID |
D004797
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| MeSH Number(s) |
E05.478.566.350.170 E05.478.566.380.360 E05.478.583.400.170 E05.601.470.350.170 E05.601.470.380.360
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| Concept/Terms |
Enzyme-Linked Immunosorbent Assay- Enzyme-Linked Immunosorbent Assay
- Assay, Enzyme-Linked Immunosorbent
- Assays, Enzyme-Linked Immunosorbent
- Enzyme Linked Immunosorbent Assay
- Enzyme-Linked Immunosorbent Assays
- Immunosorbent Assay, Enzyme-Linked
- Immunosorbent Assays, Enzyme-Linked
- ELISA
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Below are MeSH descriptors whose meaning is more general than "Enzyme-Linked Immunosorbent Assay".
Below are MeSH descriptors whose meaning is more specific than "Enzyme-Linked Immunosorbent Assay".
This graph shows the total number of publications written about "Enzyme-Linked Immunosorbent Assay" by people in this website by year, and whether "Enzyme-Linked Immunosorbent Assay" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1993 | 0 | 3 | 3 | | 1994 | 0 | 8 | 8 | | 1995 | 0 | 3 | 3 | | 1996 | 1 | 9 | 10 | | 1997 | 0 | 7 | 7 | | 1998 | 0 | 8 | 8 | | 1999 | 1 | 15 | 16 | | 2000 | 0 | 6 | 6 | | 2001 | 1 | 4 | 5 | | 2002 | 0 | 5 | 5 | | 2003 | 1 | 19 | 20 | | 2004 | 2 | 21 | 23 | | 2005 | 3 | 20 | 23 | | 2006 | 2 | 21 | 23 | | 2007 | 1 | 20 | 21 | | 2008 | 0 | 23 | 23 | | 2009 | 2 | 34 | 36 | | 2010 | 1 | 42 | 43 | | 2011 | 0 | 46 | 46 | | 2012 | 1 | 32 | 33 | | 2013 | 2 | 28 | 30 | | 2014 | 4 | 25 | 29 | | 2015 | 0 | 20 | 20 | | 2016 | 2 | 18 | 20 | | 2017 | 1 | 18 | 19 | | 2018 | 0 | 15 | 15 | | 2019 | 1 | 10 | 11 | | 2020 | 0 | 4 | 4 | | 2021 | 0 | 12 | 12 | | 2022 | 0 | 4 | 4 | | 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Enzyme-Linked Immunosorbent Assay" by people in Profiles.
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Zhou W, Graner M, Beseler C, Domashevich T, Selva S, Webster G, Ledreux A, Zizzo Z, Lundt M, Alvarez E, Yu X. Plasma IgG aggregates as biomarkers for multiple sclerosis. Clin Immunol. 2023 11; 256:109801.
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Moore RE, Wang T, Duvvuri B, Feser ML, Deane KD, Solomon JJ, Nelson JL, Demoruelle MK, Lood C. Prediction of Erosive Disease Development by Antimitochondrial Antibodies in Rheumatoid Arthritis. Arthritis Rheumatol. 2023 06; 75(6):890-899.
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Kanack AJ, Jones CG, Singh B, Leger RR, Splinter NP, Heikal NM, Pruthi RK, Chen D, George G, Abou-Ismail MY, Wool GD, Gundabolu K, Padmanabhan A. Off-the-shelf cryopreserved platelets for the detection of HIT and VITT antibodies. Blood. 2022 12 22; 140(25):2722-2729.
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Lamb MM, Paniagua-Avila A, Zacarias A, Rojop N, Chacon A, Natrajan MS, Waggoner JJ, Lopez MR, Cordon-Rosales C, Huleatt JW, Bonaparte MI, Asturias EJ, Olson D. Repeated Rapid Active Sampling Surveys Demonstrated a Rapidly Changing Zika Seroprevalence among Children in a Rural Dengue-endemic Region in Southwest Guatemala during the Zika Epidemic (2015-2016). Am J Trop Med Hyg. 2022 11 14; 107(5):1099-1106.
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Teufel LU, de Graaf DM, Netea MG, Dinarello CA, Joosten LAB, Arts RJW. Circulating interleukin-38 concentrations in healthy adults. Front Immunol. 2022; 13:964365.
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Catala A, Stone M, Busch MP, D'Alessandro A. Reprogramming of red blood cell metabolism in Zika virus-infected donors. Transfusion. 2022 05; 62(5):1045-1064.
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Gojanovich GS, Jacobson DL, Broadwell C, Karalius B, Kirmse B, Geffner ME, Jao J, Van Dyke RB, McFarland EJ, Silio M, Crain M, Gerschenson M. Associations of FGF21 and GDF15 with mitochondrial dysfunction in children living with perinatally-acquired HIV: A cross-sectional evaluation of pediatric AIDS clinical trials group 219/219C. PLoS One. 2021; 16(12):e0261563.
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Cachay R, Schwalb A, Acevedo-Rodriguez JG, Merino X, Talledo M, Suarez-Ognio L, Pezzi L, de Lamballerie X, Guerra H, Jaenisch T, Gotuzzo E. Zika Virus Seroprevalence in Two Districts of Chincha, Ica, Peru: A Cross-Sectional Study. Am J Trop Med Hyg. 2021 11 22; 106(1):192-198.
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Sempio C, Wymore E, Palmer C, Bunik M, Henthorn TK, Christians U, Klawitter J. Detection of Cannabinoids by LC-MS-MS and ELISA in Breast Milk. J Anal Toxicol. 2021 Aug 14; 45(7):686-692.
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Huey L, Andersen G, Merkel PA, Morrison TE, McCarthy M, DomBourian MG, Annen K, Dawson ED, Rowlen KL, Knight V. Evaluation of a multiplexed coronavirus antigen array for detection of SARS-CoV-2 specific IgG in COVID-19 convalescent plasma. J Immunol Methods. 2021 10; 497:113104.
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