 Mucin-5B
"Mucin-5B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A gel-forming mucin that is predominantly expressed by submucosal glands of airway tissues and the SUBLINGUAL GLAND. It is one of the principal components of high molecular weight salivary mucin.
| Descriptor ID |
D055257
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| MeSH Number(s) |
D12.644.848.750 D12.776.395.560.631.207 D12.776.850.850
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| Concept/Terms |
Mucin-5B- Mucin-5B
- Mucin 5B
- Mucin-5 Subtype B, Tracheobronchial
- Mucin 5 Subtype B, Tracheobronchial
- High Molecular Weight Salivary Mucin MG1
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Below are MeSH descriptors whose meaning is more general than "Mucin-5B".
Below are MeSH descriptors whose meaning is more specific than "Mucin-5B".
This graph shows the total number of publications written about "Mucin-5B" by people in this website by year, and whether "Mucin-5B" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2011 | 1 | 1 | 2 | | 2012 | 3 | 0 | 3 | | 2013 | 6 | 0 | 6 | | 2014 | 0 | 3 | 3 | | 2015 | 3 | 4 | 7 | | 2016 | 5 | 3 | 8 | | 2017 | 3 | 0 | 3 |
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Below are the most recent publications written about "Mucin-5B" by people in Profiles.
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Putman RK, Gudmundsson G, Araki T, Nishino M, Sigurdsson S, Gudmundsson EF, Eiríksdottír G, Aspelund T, Ross JC, San José Estépar R, Miller ER, Yamada Y, Yanagawa M, Tomiyama N, Launer LJ, Harris TB, El-Chemaly S, Raby BA, Cho MH, Rosas IO, Washko GR, Schwartz DA, Silverman EK, Gudnason V, Hatabu H, Hunninghake GM. The MUC5B promoter polymorphism is associated with specific interstitial lung abnormality subtypes. Eur Respir J. 2017 09; 50(3).
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Helling BA, Gerber AN, Kadiyala V, Sasse SK, Pedersen BS, Sparks L, Nakano Y, Okamoto T, Evans CM, Yang IV, Schwartz DA. Regulation of MUC5B Expression in Idiopathic Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2017 07; 57(1):91-99.
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Ash SY, Harmouche R, Putman RK, Ross JC, Diaz AA, Hunninghake GM, Onieva Onieva J, Martinez FJ, Choi AM, Lynch DA, Hatabu H, Rosas IO, San Jose Estepar R, Washko GR. Clinical and Genetic Associations of Objectively Identified Interstitial Changes in Smokers. Chest. 2017 10; 152(4):780-791.
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Mathai SK, Newton CA, Schwartz DA, Garcia CK. Pulmonary fibrosis in the era of stratified medicine. Thorax. 2016 12; 71(12):1154-1160.
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Evans CM, Fingerlin TE, Schwarz MI, Lynch D, Kurche J, Warg L, Yang IV, Schwartz DA. Idiopathic Pulmonary Fibrosis: A Genetic Disease That Involves Mucociliary Dysfunction of the Peripheral Airways. Physiol Rev. 2016 10; 96(4):1567-91.
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Janssen WJ, Stefanski AL, Bochner BS, Evans CM. Control of lung defence by mucins and macrophages: ancient defence mechanisms with modern functions. Eur Respir J. 2016 10; 48(4):1201-1214.
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Livraghi-Butrico A, Grubb BR, Wilkinson KJ, Volmer AS, Burns KA, Evans CM, O'Neal WK, Boucher RC. Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease. Mucosal Immunol. 2017 03; 10(2):395-407.
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Smirnova NF, Schamberger AC, Nayakanti S, Hatz R, Behr J, Eickelberg O. Detection and quantification of epithelial progenitor cell populations in human healthy and IPF lungs. Respir Res. 2016 07 16; 17(1):83.
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Nakano Y, Yang IV, Walts AD, Watson AM, Helling BA, Fletcher AA, Lara AR, Schwarz MI, Evans CM, Schwartz DA. MUC5B Promoter Variant rs35705950 Affects MUC5B Expression in the Distal Airways in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2016 Feb 15; 193(4):464-6.
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Chung JH, Peljto AL, Chawla A, Talbert JL, McKean DF, Rho BH, Fingerlin TE, Schwarz MI, Schwartz DA, Lynch DA. CT Imaging Phenotypes of Pulmonary Fibrosis in the MUC5B Promoter Site Polymorphism. Chest. 2016 05; 149(5):1215-22.
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