 Tacrolimus
"Tacrolimus" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.
| Descriptor ID |
D016559
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| MeSH Number(s) |
D02.540.505.810
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| Concept/Terms |
Anhydrous Tacrolimus- Anhydrous Tacrolimus
- Tacrolimus, Anhydrous
- Tacrolimus Anhydrous
- Anhydrous, Tacrolimus
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Below are MeSH descriptors whose meaning is more general than "Tacrolimus".
Below are MeSH descriptors whose meaning is more specific than "Tacrolimus".
This graph shows the total number of publications written about "Tacrolimus" by people in this website by year, and whether "Tacrolimus" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 4 | 4 | 8 | | 1992 | 2 | 0 | 2 | | 1993 | 0 | 2 | 2 | | 1994 | 2 | 0 | 2 | | 1995 | 7 | 0 | 7 | | 1996 | 6 | 1 | 7 | | 1997 | 2 | 2 | 4 | | 1998 | 1 | 0 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 2 | 0 | 2 | | 2001 | 4 | 3 | 7 | | 2002 | 2 | 2 | 4 | | 2003 | 3 | 4 | 7 | | 2004 | 5 | 2 | 7 | | 2005 | 10 | 2 | 12 | | 2006 | 2 | 0 | 2 | | 2007 | 3 | 2 | 5 | | 2008 | 4 | 2 | 6 | | 2009 | 3 | 2 | 5 | | 2010 | 5 | 3 | 8 | | 2011 | 1 | 4 | 5 | | 2012 | 3 | 0 | 3 | | 2013 | 7 | 2 | 9 | | 2014 | 3 | 2 | 5 | | 2015 | 6 | 0 | 6 | | 2016 | 2 | 2 | 4 | | 2017 | 5 | 0 | 5 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tacrolimus" by people in Profiles.
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Bittersohl H, Schniedewind B, Christians U, Luppa PB. A simple and highly sensitive on-line column extraction liquid chromatography-tandem mass spectrometry method for the determination of protein-unbound tacrolimus in human plasma samples. J Chromatogr A. 2018 Apr 27; 1547:45-52.
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van der Merwe Y, Faust AE, Conner I, Gu X, Feturi F, Zhao W, Leonard B, Roy S, Gorantla VS, Venkataramanan R, Washington KM, Wagner WR, Steketee MB. An Elastomeric Polymer Matrix, PEUU-Tac, Delivers Bioactive Tacrolimus Transdurally to the CNS in Rat. EBioMedicine. 2017 Dec; 26:47-59.
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Alloway RR, Vinks AA, Fukuda T, Mizuno T, King EC, Zou Y, Jiang W, Woodle ES, Tremblay S, Klawitter J, Klawitter J, Christians U. Bioequivalence between innovator and generic tacrolimus in liver and kidney transplant recipients: A randomized, crossover clinical trial. PLoS Med. 2017 Nov; 14(11):e1002428.
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Choi SW, Braun T, Henig I, Gatza E, Magenau J, Parkin B, Pawarode A, Riwes M, Yanik G, Dinarello CA, Reddy P. Vorinostat plus tacrolimus/methotrexate to prevent GVHD after myeloablative conditioning, unrelated donor HCT. Blood. 2017 10 12; 130(15):1760-1767.
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Desai VCA, Ferrand Y, Cavanaugh TM, Kelton CML, Caro JJ, Goebel J, Heaton PC. Comparative Effectiveness of Tacrolimus-Based Steroid Sparing versus Steroid Maintenance Regimens in Kidney Transplantation: Results from Discrete Event Simulation. Med Decis Making. 2017 10; 37(7):827-843.
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Mithani Z, Gralla J, Adebiyi O, Klem P, Cooper JE, Wiseman AC. De Novo Donor-Specific Antibody Formation in Tacrolimus-Based, Mycophenolate Versus Mammalian Target of Rapamycin Immunosuppressive Regimens. Exp Clin Transplant. 2018 02; 16(1):23-30.
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Milgrom SA, Nieto Y, Pinnix CC, Smith GL, Wogan CF, Rondon G, Medeiros LJ, Kebriaei P, Dabaja BS. Graft-versus-host disease after radiation therapy in patients who have undergone allogeneic stem cell transplantation: two case reports. J Med Case Rep. 2016 Jul 28; 10:209.
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Deininger KM, Vu A, Page RL, Ambardekar AV, Lindenfeld J, Aquilante CL. CYP3A pharmacogenetics and tacrolimus disposition in adult heart transplant recipients. Clin Transplant. 2016 09; 30(9):1074-81.
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Schneider L, Hanifin J, Boguniewicz M, Eichenfield LF, Spergel JM, Dakovic R, Paller AS. Study of the Atopic March: Development of Atopic Comorbidities. Pediatr Dermatol. 2016 Jul; 33(4):388-98.
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Awdishu L, Joy MS. Role of Pharmacogenomics in Kidney Disease and Injury. Adv Chronic Kidney Dis. 2016 Mar; 23(2):106-19.
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