Glycogen Synthase Kinase 3
"Glycogen Synthase Kinase 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycogen synthase kinase that was originally described as a key enzyme involved in glycogen metabolism. It regulates a diverse array of functions such as CELL DIVISION, microtubule function and APOPTOSIS.
Descriptor ID |
D038362
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MeSH Number(s) |
D05.500.117.875 D08.811.913.696.620.682.700.429.500 D08.811.913.696.620.682.700.646.625 D12.644.360.300.500 D12.776.476.081.875 D12.776.476.300.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Glycogen Synthase Kinase 3".
Below are MeSH descriptors whose meaning is more specific than "Glycogen Synthase Kinase 3".
This graph shows the total number of publications written about "Glycogen Synthase Kinase 3" by people in this website by year, and whether "Glycogen Synthase Kinase 3" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 | 2003 | 3 | 3 | 6 | 2004 | 1 | 1 | 2 | 2005 | 0 | 4 | 4 | 2006 | 1 | 2 | 3 | 2007 | 3 | 0 | 3 | 2008 | 1 | 1 | 2 | 2009 | 2 | 4 | 6 | 2010 | 4 | 1 | 5 | 2011 | 2 | 2 | 4 | 2012 | 2 | 2 | 4 | 2013 | 2 | 0 | 2 | 2014 | 2 | 2 | 4 | 2015 | 3 | 0 | 3 | 2016 | 0 | 1 | 1 | 2017 | 0 | 2 | 2 | 2018 | 3 | 0 | 3 | 2019 | 1 | 0 | 1 | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glycogen Synthase Kinase 3" by people in Profiles.
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Jungers CF, Elliff JM, Masson-Meyers DS, Phiel CJ, Origanti S. Regulation of eukaryotic translation initiation factor 6 dynamics through multisite phosphorylation by GSK3. J Biol Chem. 2020 09 04; 295(36):12796-12813.
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Nakamura M, Liu T, Husain S, Zhai P, Warren JS, Hsu CP, Matsuda T, Phiel CJ, Cox JE, Tian B, Li H, Sadoshima J. Glycogen Synthase Kinase-3a Promotes Fatty Acid Uptake and Lipotoxic Cardiomyopathy. Cell Metab. 2019 05 07; 29(5):1119-1134.e12.
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Bhattacharjee R, Goswami S, Dey S, Gangoda M, Brothag C, Eisa A, Woodgett J, Phiel C, Kline D, Vijayaraghavan S. Isoform-specific requirement for GSK3a in sperm for male fertility. Biol Reprod. 2018 08 01; 99(2):384-394.
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Faulds KJ, Egelston JN, Sedivy LJ, Mitchell MK, Garimella S, Kozlowski H, D'Alessandro A, Hansen KC, Balsbaugh JL, Phiel CJ. Glycogen synthase kinase-3 (GSK-3) activity regulates mRNA methylation in mouse embryonic stem cells. J Biol Chem. 2018 07 06; 293(27):10731-10743.
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Gonzalez Malagon SG, Lopez Mu?oz AM, Doro D, Bolger TG, Poon E, Tucker ER, Adel Al-Lami H, Krause M, Phiel CJ, Chesler L, Liu KJ. Glycogen synthase kinase 3 controls migration of the neural crest lineage in mouse and Xenopus. Nat Commun. 2018 03 19; 9(1):1126.
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Prieto-Almeida F, Panveloski-Costa AC, Crunfli F, da Silva Teixeira S, Nunes MT, Torr?o ADS. Thyroid hormone improves insulin signaling and reduces the activation of neurodegenerative pathway in the hippocampus of diabetic adult male rats. Life Sci. 2018 01 01; 192:253-258.
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Luckey SW, Haines CD, Konhilas JP, Luczak ED, Messmer-Kratzsch A, Leinwand LA. Cyclin D2 is a critical mediator of exercise-induced cardiac hypertrophy. Exp Biol Med (Maywood). 2017 Dec; 242(18):1820-1830.
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Irimia JM, Meyer CM, Segvich DM, Surendran S, DePaoli-Roach AA, Morral N, Roach PJ. Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice. J Biol Chem. 2017 06 23; 292(25):10455-10464.
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Martin PM, Stanley RE, Ross AP, Freitas AE, Moyer CE, Brumback AC, Iafrati J, Stapornwongkul KS, Dominguez S, Kivim?e S, Mulligan KA, Pirooznia M, McCombie WR, Potash JB, Zandi PP, Purcell SM, Sanders SJ, Zuo Y, Sohal VS, Cheyette BNR. DIXDC1 contributes to psychiatric susceptibility by regulating dendritic spine and glutamatergic synapse density via GSK3 and Wnt/?-catenin signaling. Mol Psychiatry. 2018 02; 23(2):467-475.
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Pandey MK, DeGrado TR. Glycogen Synthase Kinase-3 (GSK-3)-Targeted Therapy and Imaging. Theranostics. 2016; 6(4):571-93.
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