 Fluoxetine
"Fluoxetine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
| Descriptor ID |
D005473
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| MeSH Number(s) |
D02.092.831.280
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| Concept/Terms |
Fluoxetine- Fluoxetine
- Fluoxetin
- N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine
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Below are MeSH descriptors whose meaning is more general than "Fluoxetine".
Below are MeSH descriptors whose meaning is more specific than "Fluoxetine".
This graph shows the total number of publications written about "Fluoxetine" by people in this website by year, and whether "Fluoxetine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1997 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1999 | 2 | 1 | 3 | | 2003 | 1 | 0 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 0 | 2 | 2 | | 2007 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 2 | 1 | 3 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2013 | 1 | 1 | 2 | | 2015 | 2 | 1 | 3 | | 2016 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 2 | 0 | 2 | | 2019 | 1 | 1 | 2 | | 2021 | 1 | 0 | 1 | | 2023 | 2 | 0 | 2 |
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Below are the most recent publications written about "Fluoxetine" by people in Profiles.
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Payet JM, Stevens L, Russo AM, Jaehne EJ, van den Buuse M, Kent S, Lowry CA, Baratta MV, Hale MW. The Role of Dorsal Raphe Nucleus Serotonergic Systems in Emotional Learning and Memory in Male BALB/c Mice. Neuroscience. 2023 Dec 01; 534:1-15.
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Haque TT, Taruselli MT, Kee SA, Dailey JM, Pondicherry N, Gajewski-Kurdziel PA, Zellner MP, Stephenson DJ, MacKnight HP, Straus DB, Kankaria R, Jackson KG, Chumanevich AP, Fukuoka Y, Schwartz LB, Blakely RD, Oskeritzian CA, Chalfant CE, Martin RK, Ryan JJ. Fluoxetine restrains allergic inflammation by targeting an Fc?RI-ATP positive feedback loop in mast cells. Sci Signal. 2023 09 12; 16(802):eabc9089.
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Payet JM, Wilson KE, Russo AM, Angiolino A, Kavanagh-Ryan W, Kent S, Lowry CA, Hale MW. Involvement of dorsal raphe nucleus serotonergic systems in social approach-avoidance behaviour and in the response to fluoxetine treatment in peri-adolescent female BALB/c mice. Behav Brain Res. 2021 06 25; 408:113268.
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Ramsteijn AS, Ja?arevic E, Houwing DJ, Bale TL, Olivier JD. Antidepressant treatment with fluoxetine during pregnancy and lactation modulates the gut microbiome and metabolome in a rat model relevant to depression. Gut Microbes. 2020 07 03; 11(4):735-753.
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Orrico-Sanchez A, Chausset-Boissarie L, Alves de Sousa R, Coutens B, Rezai Amin S, Vialou V, Louis F, Hessani A, Dansette PM, Zornoza T, Gruszczynski C, Giros B, Guiard BP, Acher F, Pietrancosta N, Gautron S. Antidepressant efficacy of a selective organic cation transporter blocker in a mouse model of depression. Mol Psychiatry. 2020 06; 25(6):1245-1259.
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Hinckley JD, Riggs P. Integrated Treatment of Adolescents with Co-occurring Depression and Substance Use Disorder. Child Adolesc Psychiatr Clin N Am. 2019 07; 28(3):461-472.
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Schlansky K, Facer B, Tanguturi YC, Cundiff AW, Fuchs DC. Pediatric Acute-Onset Neuropsychiatric Syndrome and Catatonia: A Case Report. Psychosomatics. 2020 Jan - Feb; 61(1):86-91.
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Van Dyke AM, Francis TC, Chen H, Bailey AM, Thompson SM. RETRACTED: Chronic fluoxetine treatment in vivo enhances excitatory synaptic transmission in the hippocampus. Neuropharmacology. 2019 05 15; 150:38-45.
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Messacar K, Sillau S, Hopkins SE, Otten C, Wilson-Murphy M, Wong B, Santoro JD, Treister A, Bains HK, Torres A, Zabrocki L, Glanternik JR, Hurst AL, Martin JA, Schreiner T, Makhani N, DeBiasi RL, Kruer MC, Tremoulet AH, Van Haren K, Desai J, Benson LA, Gorman MP, Abzug MJ, Tyler KL, Dominguez SR. Safety, tolerability, and efficacy of fluoxetine as an antiviral for acute flaccid myelitis. Neurology. 2019 04 30; 92(18):e2118-e2126.
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Payet JM, Burnie E, Sathananthan NJ, Russo AM, Lawther AJ, Kent S, Lowry CA, Hale MW. Exposure to Acute and Chronic Fluoxetine has Differential Effects on Sociability and Activity of Serotonergic Neurons in the Dorsal Raphe Nucleus of Juvenile Male BALB/c Mice. Neuroscience. 2018 08 21; 386:1-15.
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