 E2F2 Transcription Factor
"E2F2 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An E2F transcription factor that interacts directly with RETINOBLASTOMA PROTEIN and CYCLIN A. E2F2 activates GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis.
| Descriptor ID |
D050703
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| MeSH Number(s) |
D12.776.930.211.625
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| Concept/Terms |
E2F2 Transcription Factor- E2F2 Transcription Factor
- Transcription Factor, E2F2
- Transcription Factor E2F-2
- E2F-2, Transcription Factor
- Transcription Factor E2F 2
- E2F Transcription Factor 2 Protein
- E2F2 Protein
- E2F-2 Protein
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Below are MeSH descriptors whose meaning is more general than "E2F2 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "E2F2 Transcription Factor".
This graph shows the total number of publications written about "E2F2 Transcription Factor" by people in this website by year, and whether "E2F2 Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2002 | 0 | 2 | 2 | | 2005 | 0 | 2 | 2 | | 2008 | 0 | 1 | 1 | | 2009 | 2 | 0 | 2 | | 2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "E2F2 Transcription Factor" by people in Profiles.
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Wichmann A, Uyetake L, Su TT. E2F1 and E2F2 have opposite effects on radiation-induced p53-independent apoptosis in Drosophila. Dev Biol. 2010 Oct 01; 346(1):80-9.
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Zhou J, Zhu Y, Cheng M, Dinesh D, Thorne T, Poh KK, Liu D, Botros C, Tang YL, Reisdorph N, Kishore R, Losordo DW, Qin G. Regulation of vascular contractility and blood pressure by the E2F2 transcription factor. Circulation. 2009 Sep 29; 120(13):1213-21.
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Rempel RE, Mori S, Gasparetto M, Glozak MA, Andrechek ER, Adler SB, Laakso NM, Lagoo AS, Storms R, Smith C, Nevins JR. A role for E2F activities in determining the fate of Myc-induced lymphomagenesis. PLoS Genet. 2009 Sep; 5(9):e1000640.
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Tessem JS, Jensen JN, Pelli H, Dai XM, Zong XH, Stanley ER, Jensen J, DeGregori J. Critical roles for macrophages in islet angiogenesis and maintenance during pancreatic degeneration. Diabetes. 2008 Jun; 57(6):1605-17.
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Bilousova G, Marusyk A, Porter CC, Cardiff RD, DeGregori J. Impaired DNA replication within progenitor cell pools promotes leukemogenesis. PLoS Biol. 2005 Dec; 3(12):e401.
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DeRyckere D, DeGregori J. E2F1 and E2F2 are differentially required for homeostasis-driven and antigen-induced T cell proliferation in vivo. J Immunol. 2005 Jul 15; 175(2):647-55.
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DeGregori J. The genetics of the E2F family of transcription factors: shared functions and unique roles. Biochim Biophys Acta. 2002 Jun 21; 1602(2):131-50.
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Tyagi A, Agarwal C, Agarwal R. Inhibition of retinoblastoma protein (Rb) phosphorylation at serine sites and an increase in Rb-E2F complex formation by silibinin in androgen-dependent human prostate carcinoma LNCaP cells: role in prostate cancer prevention. Mol Cancer Ther. 2002 May; 1(7):525-32.
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Zhu JW, Field SJ, Gore L, Thompson M, Yang H, Fujiwara Y, Cardiff RD, Greenberg M, Orkin SH, DeGregori J. E2F1 and E2F2 determine thresholds for antigen-induced T-cell proliferation and suppress tumorigenesis. Mol Cell Biol. 2001 Dec; 21(24):8547-64.
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Smith DS, Leone G, DeGregori J, Ahmed MN, Qumsiyeh MB, Nevins JR. Induction of DNA replication in adult rat neurons by deregulation of the retinoblastoma/E2F G1 cell cycle pathway. Cell Growth Differ. 2000 Dec; 11(12):625-33.
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