 Allopurinol
"Allopurinol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A XANTHINE OXIDASE inhibitor that decreases URIC ACID production. It also acts as an antimetabolite on some simpler organisms.
| Descriptor ID |
D000493
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| MeSH Number(s) |
D03.633.100.759.160
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Allopurinol".
Below are MeSH descriptors whose meaning is more specific than "Allopurinol".
This graph shows the total number of publications written about "Allopurinol" by people in this website by year, and whether "Allopurinol" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 0 | 2 | 2 | | 1992 | 0 | 1 | 1 | | 1993 | 0 | 1 | 1 | | 1994 | 0 | 2 | 2 | | 1995 | 0 | 2 | 2 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 1 | 0 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 2 | 2 | | 2004 | 1 | 2 | 3 | | 2005 | 0 | 2 | 2 | | 2006 | 1 | 4 | 5 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 2 | 0 | 2 | | 2010 | 2 | 2 | 4 | | 2011 | 3 | 5 | 8 | | 2012 | 0 | 2 | 2 | | 2013 | 0 | 1 | 1 | | 2014 | 2 | 1 | 3 | | 2015 | 3 | 1 | 4 | | 2016 | 1 | 0 | 1 | | 2018 | 3 | 1 | 4 | | 2019 | 1 | 2 | 3 | | 2020 | 2 | 0 | 2 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Allopurinol" by people in Profiles.
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Floege J, Johnson RJ. Hyperuricemia and progression of chronic kidney disease: to treat or not to treat? Kidney Int. 2021 01; 99(1):14-16.
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Kang DH, Sanchez-Lozada LG, Johnson RJ. Allopurinol and Chronic Kidney Disease. N Engl J Med. 2020 Oct 22; 383(17):1687-1688.
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Doria A, Galecki AT, Spino C, Pop-Busui R, Cherney DZ, Lingvay I, Parsa A, Rossing P, Sigal RJ, Afkarian M, Aronson R, Caramori ML, Crandall JP, de Boer IH, Elliott TG, Goldfine AB, Haw JS, Hirsch IB, Karger AB, Maahs DM, McGill JB, Molitch ME, Perkins BA, Polsky S, Pragnell M, Robiner WN, Rosas SE, Senior P, Tuttle KR, Umpierrez GE, Wallia A, Weinstock RS, Wu C, Mauer M. Serum Urate Lowering with Allopurinol and Kidney Function in Type 1 Diabetes. N Engl J Med. 2020 06 25; 382(26):2493-2503.
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García-Arroyo FE, Monroy-Sánchez F, Muñoz-Jiménez I, Gonzaga G, Andrés-Hernando A, Zazueta C, Juárez-Rojas JG, Lanaspa MA, Johnson RJ, Sánchez-Lozada LG. Allopurinol Prevents the Lipogenic Response Induced by an Acute Oral Fructose Challenge in Short-Term Fructose Fed Rats. Biomolecules. 2019 10 11; 9(10).
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Ko J, Kang HJ, Kim DA, Kim MJ, Ryu ES, Lee S, Ryu JH, Roncal C, Johnson RJ, Kang DH. Uric acid induced the phenotype transition of vascular endothelial cells via induction of oxidative stress and glycocalyx shedding. FASEB J. 2019 12; 33(12):13334-13345.
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Brigham MD, Radeck LP, Mendonca CM, Lang I, Li JW, Kent JD, LaMoreaux B, Mandell BF, Johnson RJ. Gout Severity in Recipients of Kidney Transplant. Transplant Proc. 2019 Jul - Aug; 51(6):1816-1821.
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Sánchez-Lozada LG, García-Arroyo FE, Gonzaga G, Silverio O, Blas-Marron MG, Muñoz-Jimenez I, Tapia E, Osorio-Alonso H, Madero M, Roncal-Jiménez CA, Weiss I, Glaser J, Johnson RJ. Kidney Injury from Recurrent Heat Stress and Rhabdomyolysis: Protective Role of Allopurinol and Sodium Bicarbonate. Am J Nephrol. 2018; 48(5):339-348.
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Andrews ES, Perrenoud L, Nowak KL, You Z, Pasch A, Chonchol M, Kendrick J, Jalal D. Examining the effects of uric acid-lowering on markers vascular of calcification and CKD-MBD; A post-hoc analysis of a randomized clinical trial. PLoS One. 2018; 13(10):e0205831.
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Serpico MR, Maltz R, Crandall W, Bricker J, Dotson JL, Kim SC, Boyle B. Thiopurine Optimization Through Combination With Allopurinol in Children With Inflammatory Bowel Diseases. J Pediatr Gastroenterol Nutr. 2018 09; 67(3):341-345.
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Roncal-Jimenez CA, Sato Y, Milagres T, Andres Hernando A, García G, Bjornstad P, Dawson JB, Sorensen C, Newman L, Krisher L, Madero M, Glaser J, Gárcía-Trabanino R, Romero EJ, Song Z, Jensen T, Kuwabara M, Rodriguez-Iturbe B, Sanchez-Lozada LG, Lanaspa MA, Johnson RJ. Experimental heat stress nephropathy and liver injury are improved by allopurinol. Am J Physiol Renal Physiol. 2018 09 01; 315(3):F726-F733.
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