 Helix-Loop-Helix Motifs
"Helix-Loop-Helix Motifs" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Recurring supersecondary structures characterized by 20 amino acids folding into two alpha helices connected by a non-helical "loop" segment. They are found in many sequence-specific DNA-BINDING PROTEINS and in CALCIUM-BINDING PROTEINS.
| Descriptor ID |
D018257
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| MeSH Number(s) |
G02.111.570.820.709.275.500.360
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| Concept/Terms |
Helix-Loop-Helix Motifs- Helix-Loop-Helix Motifs
- Helix Loop Helix Motifs
- Motif, Helix-Loop-Helix
- Helix-Loop-Helix Domains
- Helix Loop Helix Domains
- Helix-Loop-Helix Motif
- Helix Loop Helix Motif
- Helix-Loop-Helix Domain
- Helix Loop Helix Domain
- HLH Motifs
- HLH Motif
- Motif, HLH
- Motifs, HLH
- Motifs, Helix-Loop-Helix
- Motifs, Helix Loop Helix
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Below are MeSH descriptors whose meaning is more general than "Helix-Loop-Helix Motifs".
Below are MeSH descriptors whose meaning is more specific than "Helix-Loop-Helix Motifs".
This graph shows the total number of publications written about "Helix-Loop-Helix Motifs" by people in this website by year, and whether "Helix-Loop-Helix Motifs" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 1998 | 0 | 2 | 2 | | 2000 | 1 | 0 | 1 | | 2001 | 0 | 1 | 1 | | 2002 | 1 | 1 | 2 | | 2003 | 0 | 2 | 2 | | 2005 | 0 | 1 | 1 |
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Below are the most recent publications written about "Helix-Loop-Helix Motifs" by people in Profiles.
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Banerjee A, MacKinnon R. Inferred motions of the S3a helix during voltage-dependent K+ channel gating. J Mol Biol. 2008 Sep 05; 381(3):569-80.
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Brzezinski JA, Brown NL, Tanikawa A, Bush RA, Sieving PA, Vitaterna MH, Takahashi JS, Glaser T. Loss of circadian photoentrainment and abnormal retinal electrophysiology in Math5 mutant mice. Invest Ophthalmol Vis Sci. 2005 Jul; 46(7):2540-51.
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Park HC, Appel B. Delta-Notch signaling regulates oligodendrocyte specification. Development. 2003 Aug; 130(16):3747-55.
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Ruest LB, Dager M, Yanagisawa H, Charit? J, Hammer RE, Olson EN, Yanagisawa M, Clouthier DE. dHAND-Cre transgenic mice reveal specific potential functions of dHAND during craniofacial development. Dev Biol. 2003 May 15; 257(2):263-77.
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Kabos P, Kabosova A, Neuman T. Neuronal injury affects expression of helix-loop-helix transcription factors. Neuroreport. 2002 Dec 20; 13(18):2385-8.
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Desveaux D, Allard J, Brisson N, Sygusch J. A new family of plant transcription factors displays a novel ssDNA-binding surface. Nat Struct Biol. 2002 Jul; 9(7):512-7.
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Kabos P, Kabosova A, Neuman T. Blocking HES1 expression initiates GABAergic differentiation and induces the expression of p21(CIP1/WAF1) in human neural stem cells. J Biol Chem. 2002 Mar 15; 277(11):8763-6.
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Kim WY, Fritzsch B, Serls A, Bakel LA, Huang EJ, Reichardt LF, Barth DS, Lee JE. NeuroD-null mice are deaf due to a severe loss of the inner ear sensory neurons during development. Development. 2001 Feb; 128(3):417-26.
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Schwitzgebel VM, Scheel DW, Conners JR, Kalamaras J, Lee JE, Anderson DJ, Sussel L, Johnson JD, German MS. Expression of neurogenin3 reveals an islet cell precursor population in the pancreas. Development. 2000 Aug; 127(16):3533-42.
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Yu AY, Frid MG, Shimoda LA, Wiener CM, Stenmark K, Semenza GL. Temporal, spatial, and oxygen-regulated expression of hypoxia-inducible factor-1 in the lung. Am J Physiol. 1998 10; 275(4):L818-26.
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