 Platelet Activation
"Platelet Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A series of progressive, overlapping events, triggered by exposure of the PLATELETS to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
| Descriptor ID |
D015539
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| MeSH Number(s) |
G09.188.390.600
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| Concept/Terms |
Platelet Activation- Platelet Activation
- Activation, Platelet
- Activations, Platelet
- Platelet Activations
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Below are MeSH descriptors whose meaning is more general than "Platelet Activation".
Below are MeSH descriptors whose meaning is more specific than "Platelet Activation".
This graph shows the total number of publications written about "Platelet Activation" by people in this website by year, and whether "Platelet Activation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1999 | 0 | 1 | 1 | | 2003 | 1 | 1 | 2 | | 2005 | 1 | 1 | 2 | | 2007 | 1 | 0 | 1 | | 2009 | 2 | 2 | 4 | | 2010 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2015 | 1 | 1 | 2 | | 2016 | 1 | 0 | 1 | | 2017 | 2 | 1 | 3 | | 2018 | 1 | 2 | 3 | | 2019 | 0 | 2 | 2 | | 2020 | 1 | 3 | 4 |
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Below are the most recent publications written about "Platelet Activation" by people in Profiles.
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Matthay ZA, Fields AT, Nunez-Garcia B, Patel MH, Cohen MJ, Callcut RA, Kornblith LZ. Dynamic effects of calcium on in vivo and ex vivo platelet behavior after trauma. J Trauma Acute Care Surg. 2020 11; 89(5):871-879.
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Starr NE, Matthay ZA, Fields AT, Nunez-Garcia B, Callcut RA, Cohen MJ, Kornblith LZ. Identification of injury and shock driven effects on ex vivo platelet aggregometry: A cautionary tale of phenotyping. J Trauma Acute Care Surg. 2020 07; 89(1):20-28.
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Kornblith LZ, Bainton CMV, Fields AT, Matthay ZA, Magid NT, Nunez-Garcia B, Prakash A, Kurien PA, Callcut RA, Cohen MJ, Bainton RJ. A journey upstream: Fluctuating platelet-specific genes in cell-free plasma as proof-of-concept for using ribonucleic acid sequencing to improve understanding of postinjury platelet biology. J Trauma Acute Care Surg. 2020 06; 88(6):742-751.
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Davizon-Castillo P, Allawzi A, Sorrells M, Fisher S, Baltrunaite K, Neeves K, Nozik-Grayck E, DiPaola J, Delaney C. Platelet activation in experimental murine neonatal pulmonary hypertension. Physiol Rep. 2020 03; 8(5):e14386.
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Coleman JR, Moore EE, Kelher MR, Samuels JM, Cohen MJ, Sauaia A, Banerjee A, Silliman CC, Peltz ED. Female platelets have distinct functional activity compared with male platelets: Implications in transfusion practice and treatment of trauma-induced coagulopathy. J Trauma Acute Care Surg. 2019 11; 87(5):1052-1060.
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Davizon-Castillo P, McMahon B, Aguila S, Bark D, Ashworth K, Allawzi A, Campbell RA, Montenont E, Nemkov T, D'Alessandro A, Clendenen N, Shih L, Sanders NA, Higa K, Cox A, Padilla-Romo Z, Hernandez G, Wartchow E, Trahan GD, Nozik-Grayck E, Jones K, Pietras EM, DeGregori J, Rondina MT, Di Paola J. TNF-a-driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging. Blood. 2019 08 29; 134(9):727-740.
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Al-Sofiani ME, Yanek LR, Faraday N, Kral BG, Mathias R, Becker LC, Becker DM, Vaidya D, Kalyani RR. Diabetes and Platelet Response to Low-Dose Aspirin. J Clin Endocrinol Metab. 2018 12 01; 103(12):4599-4608.
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Tunjungputri RN, Li Y, de Groot PG, Dinarello CA, Smeekens SP, Jaeger M, Doppenberg-Oosting M, Cruijsen M, Lemmers H, Toenhake-Dijkstra H, Aguirre-Gamboa R, Kumar V, Wijmenga C, Joosten LAB, Netea MG, van der Ven A, de Mast Q. The Inter-Relationship of Platelets with Interleukin-1ß-Mediated Inflammation in Humans. Thromb Haemost. 2018 Dec; 118(12):2112-2125.
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Branchford BR, Stalker TJ, Law L, Acevedo G, Sather S, Brzezinski C, Wilson KM, Minson K, Lee-Sherick AB, Davizon-Castillo P, Ng C, Zhang W, Neeves KB, Lentz SR, Wang X, Frye SV, Shelton Earp H, DeRyckere D, Brass LF, Graham DK, Di Paola JA. The small-molecule MERTK inhibitor UNC2025 decreases platelet activation and prevents thrombosis. J Thromb Haemost. 2018 02; 16(2):352-363.
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Vanderbilt CM, McFarland C, Lind SE. Evaluation of a Reflex Testing Algorithm for Suspected Heparin-Induced Thrombocytopenia. Am J Clin Pathol. 2017 Nov 02; 148(5):390-397.
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