 Cardiolipins
"Cardiolipins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Acidic phospholipids composed of two molecules of phosphatidic acid covalently linked to a molecule of glycerol. They occur primarily in mitochondrial inner membranes and in bacterial plasma membranes. They are the main antigenic components of the Wassermann-type antigen that is used in nontreponemal SYPHILIS SERODIAGNOSIS.
| Descriptor ID |
D002308
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| MeSH Number(s) |
D10.570.755.375.760.400.885.185 D23.050.550.480.330
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cardiolipins".
Below are MeSH descriptors whose meaning is more specific than "Cardiolipins".
This graph shows the total number of publications written about "Cardiolipins" by people in this website by year, and whether "Cardiolipins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 2 | 0 | 2 | | 2008 | 1 | 3 | 4 | | 2009 | 2 | 2 | 4 | | 2010 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 3 | 0 | 3 | | 2013 | 1 | 1 | 2 | | 2014 | 1 | 0 | 1 | | 2015 | 2 | 1 | 3 | | 2016 | 3 | 0 | 3 | | 2017 | 0 | 3 | 3 | | 2018 | 1 | 1 | 2 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cardiolipins" by people in Profiles.
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Garcia AM, McPhaul JC, Sparagna GC, Jeffrey DA, Jonscher R, Patel SS, Sucharov CC, Stauffer BL, Miyamoto SD, Chatfield KC. Alteration of cardiolipin biosynthesis and remodeling in single right ventricle congenital heart disease. Am J Physiol Heart Circ Physiol. 2020 04 01; 318(4):H787-H800.
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Melby ES, Allen C, Foreman-Ortiz IU, Caudill ER, Kuech TR, Vartanian AM, Zhang X, Murphy CJ, Hernandez R, Pedersen JA. Peripheral Membrane Proteins Facilitate Nanoparticle Binding at Lipid Bilayer Interfaces. Langmuir. 2018 09 11; 34(36):10793-10805.
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Pennington ER, Sullivan EM, Fix A, Dadoo S, Zeczycki TN, DeSantis A, Schlattner U, Coleman RA, Chicco AJ, Brown DA, Shaikh SR. Proteolipid domains form in biomimetic and cardiac mitochondrial vesicles and are regulated by cardiolipin concentration but not monolyso-cardiolipin. J Biol Chem. 2018 10 12; 293(41):15933-15946.
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Sullivan EM, Pennington ER, Sparagna GC, Torres MJ, Neufer PD, Harris M, Washington J, Anderson EJ, Zeczycki TN, Brown DA, Shaikh SR. Docosahexaenoic acid lowers cardiac mitochondrial enzyme activity by replacing linoleic acid in the phospholipidome. J Biol Chem. 2018 01 12; 293(2):466-483.
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Adams HM, Joyce LR, Guan Z, Akins RL, Palmer KL. Streptococcus mitis and S. oralis Lack a Requirement for CdsA, the Enzyme Required for Synthesis of Major Membrane Phospholipids in Bacteria. Antimicrob Agents Chemother. 2017 05; 61(5).
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Sullivan EM, Fix A, Crouch MJ, Sparagna GC, Zeczycki TN, Brown DA, Shaikh SR. Murine diet-induced obesity remodels cardiac and liver mitochondrial phospholipid acyl chains with differential effects on respiratory enzyme activity. J Nutr Biochem. 2017 07; 45:94-103.
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Romantsov T, Culham DE, Caplan T, Garner J, Hodges RS, Wood JM. ProP-ProP and ProP-phospholipid interactions determine the subcellular distribution of osmosensing transporter ProP in Escherichia coli. Mol Microbiol. 2017 02; 103(3):469-482.
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Cole LK, Mejia EM, Vandel M, Sparagna GC, Claypool SM, Dyck-Chan L, Klein J, Hatch GM. Impaired Cardiolipin Biosynthesis Prevents Hepatic Steatosis and Diet-Induced Obesity. Diabetes. 2016 Nov; 65(11):3289-3300.
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Dolinsky VW, Cole LK, Sparagna GC, Hatch GM. Cardiac mitochondrial energy metabolism in heart failure: Role of cardiolipin and sirtuins. Biochim Biophys Acta. 2016 10; 1861(10):1544-54.
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Mejia EM, Chau S, Sparagna GC, Sipione S, Hatch GM. Reduced Mitochondrial Function in Human Huntington Disease Lymphoblasts is Not Due to Alterations in Cardiolipin Metabolism or Mitochondrial Supercomplex Assembly. Lipids. 2016 05; 51(5):561-9.
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