 Immunodominant Epitopes
"Immunodominant Epitopes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Subunits of the antigenic determinant that are most easily recognized by the immune system and thus most influence the specificity of the induced antibody.
| Descriptor ID |
D016056
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| MeSH Number(s) |
D23.050.550.500
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| Concept/Terms |
Immunodominant Epitopes- Immunodominant Epitopes
- Immunodominant Determinants
- Determinants, Immunodominant
- Immunodominant Domains
- Domains, Immunodominant
- Immunodominant Sites
- Sites, Immunodominant
- Immunodominant Regions
- Regions, Immunodominant
- Antigenic Determinants, Immunodominant
- Determinants, Immunodominant Antigenic
- Immunodominant Antigenic Determinants
- Epitopes, Immunodominant
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Below are MeSH descriptors whose meaning is more general than "Immunodominant Epitopes".
Below are MeSH descriptors whose meaning is more specific than "Immunodominant Epitopes".
This graph shows the total number of publications written about "Immunodominant Epitopes" by people in this website by year, and whether "Immunodominant Epitopes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 1998 | 1 | 1 | 2 | | 2001 | 0 | 1 | 1 | | 2002 | 1 | 2 | 3 | | 2003 | 1 | 1 | 2 | | 2004 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 0 | 2 | 2 | | 2009 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2012 | 1 | 2 | 3 | | 2017 | 2 | 0 | 2 | | 2020 | 1 | 0 | 1 | | 2021 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Immunodominant Epitopes" by people in Profiles.
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Heffron AS, McIlwain SJ, Amjadi MF, Baker DA, Khullar S, Armbrust T, Halfmann PJ, Kawaoka Y, Sethi AK, Palmenberg AC, Shelef MA, O'Connor DH, Ong IM. The landscape of antibody binding in SARS-CoV-2 infection. PLoS Biol. 2021 06; 19(6):e3001265.
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Sant S, Quiñones-Parra SM, Koutsakos M, Grant EJ, Loudovaris T, Mannering SI, Crowe J, van de Sandt CE, Rimmelzwaan GF, Rossjohn J, Gras S, Loh L, Nguyen THO, Kedzierska K. HLA-B*27:05 alters immunodominance hierarchy of universal influenza-specific CD8+ T cells. PLoS Pathog. 2020 08; 16(8):e1008714.
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Wroblewski EE, Guethlein LA, Norman PJ, Li Y, Shaw CM, Han AS, Ndjango JN, Ahuka-Mundeke S, Georgiev AV, Peeters M, Hahn BH, Parham P. Bonobos Maintain Immune System Diversity with Three Functional Types of MHC-B. J Immunol. 2017 May 01; 198(9):3480-3493.
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Vogel AL, Knier B, Lammens K, Kalluri SR, Kuhlmann T, Bennett JL, Korn T. Deletional tolerance prevents AQP4-directed autoimmunity in mice. Eur J Immunol. 2017 03; 47(3):458-469.
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Capitini CM, Nasholm NM, Duncan BB, Guimond M, Fry TJ. Graft-versus-host disease impairs vaccine responses through decreased CD4+ and CD8+ T cell proliferation and increased perforin-mediated CD8+ T cell apoptosis. J Immunol. 2013 Feb 01; 190(3):1351-9.
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Arellano B, Hussain R, Zacharias T, Yoon J, David C, Zein S, Steinman L, Forsthuber T, Greenberg BM, Lambracht-Washington D, Ritchie AM, Bennett JL, Stüve O. Human aquaporin 4281-300 is the immunodominant linear determinant in the context of HLA-DRB1*03:01: relevance for diagnosing and monitoring patients with neuromyelitis optica. Arch Neurol. 2012 Sep; 69(9):1125-31.
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Vitello AM, Du Y, Buttrick PM, Walker LA. Serendipitous discovery of a novel protein signaling mechanism in heart failure. Biochem Biophys Res Commun. 2012 May 11; 421(3):431-5.
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Jordan KR, McMahan RH, Kemmler CB, Kappler JW, Slansky JE. Peptide vaccines prevent tumor growth by activating T cells that respond to native tumor antigens. Proc Natl Acad Sci U S A. 2010 Mar 09; 107(10):4652-7.
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Zhang L, Jasinski JM, Kobayashi M, Davenport B, Johnson K, Davidson H, Nakayama M, Haskins K, Eisenbarth GS. Analysis of T cell receptor beta chains that combine with dominant conserved TRAV5D-4*04 anti-insulin B:9-23 alpha chains. J Autoimmun. 2009 Aug; 33(1):42-9.
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Pan ZJ, Davis K, Maier S, Bachmann MP, Kim-Howard XR, Keech C, Gordon TP, McCluskey J, Farris AD. Neo-epitopes are required for immunogenicity of the La/SS-B nuclear antigen in the context of late apoptotic cells. Clin Exp Immunol. 2006 Feb; 143(2):237-48.
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