 Tuftsin
"Tuftsin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
N(2)-((1-(N(2)-L-Threonyl)-L-lysyl)-L-prolyl)-L-arginine. A tetrapeptide produced in the spleen by enzymatic cleavage of a leukophilic gamma-globulin. It stimulates the phagocytic activity of blood polymorphonuclear leukocytes and neutrophils in particular. The peptide is located in the Fd fragment of the gamma-globulin molecule.
| Descriptor ID |
D014405
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| MeSH Number(s) |
D12.644.456.840 D12.644.541.500.650.750 D12.776.124.486.485.397.500 D12.776.124.486.485.680.650.750 D12.776.124.790.651.397.500 D12.776.124.790.651.680.650.750 D12.776.377.715.548.397.500 D12.776.377.715.548.680.650.750
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| Concept/Terms |
Tuftsin- Tuftsin
- L-Threonyl-L-Lysyl-L-Prolyl-L-Arginine
- Taftsin
- L-Thr-L-Lys-L-Pro-L-Arg
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Below are MeSH descriptors whose meaning is more general than "Tuftsin".
Below are MeSH descriptors whose meaning is more specific than "Tuftsin".
This graph shows the total number of publications written about "Tuftsin" by people in this website by year, and whether "Tuftsin" was a major or minor topic of these publications.
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Below are the most recent publications written about "Tuftsin" by people in Profiles.
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Gottlieb P, Tzehoval E, Feldman M, Segal S, Fridkin M. Peptide fragments from the tuftsin containing domain of immunoglobulin G synthesis and biological activity. Biochem Biophys Res Commun. 1983 Aug 30; 115(1):193-200.
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Catane R, Schlanger S, Weiss L, Penchas S, Fuks Z, Treves AJ, Gottlieb P, Fridkin M. Toxicology and antitumor activity of tuftsin. Ann N Y Acad Sci. 1983; 419:251-60.
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Gottlieb P, Tzehoval E, Feldman M, Segal S, Fridkin M. Tuftsin binding to various macrophage hybridomas. Ann N Y Acad Sci. 1983; 419:107-13.
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Klempner MS, Dinarello CA, Henderson WR, Gallin JI. Stimulation of neutrophil oxygen-dependent metabolism by human leukocytic pyrogen. J Clin Invest. 1979 Oct; 64(4):996-1002.
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