 Reactive Oxygen Species
"Reactive Oxygen Species" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Molecules or ions formed by the incomplete one-electron reduction of oxygen. These reactive oxygen intermediates include SINGLET OXYGEN; SUPEROXIDES; PEROXIDES; HYDROXYL RADICAL; and HYPOCHLOROUS ACID. They contribute to the microbicidal activity of PHAGOCYTES, regulation of SIGNAL TRANSDUCTION and GENE EXPRESSION, and the oxidative damage to NUCLEIC ACIDS; PROTEINS; and LIPIDS.
| Descriptor ID |
D017382
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| MeSH Number(s) |
D01.339.431 D01.650.775
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| Concept/Terms |
Reactive Oxygen Species- Reactive Oxygen Species
- Oxygen Species, Reactive
- Active Oxygen
- Oxygen, Active
- Oxygen Radicals
- Pro-Oxidants
- Pro Oxidants
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Below are MeSH descriptors whose meaning is more general than "Reactive Oxygen Species".
Below are MeSH descriptors whose meaning is more specific than "Reactive Oxygen Species".
This graph shows the total number of publications written about "Reactive Oxygen Species" by people in this website by year, and whether "Reactive Oxygen Species" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 1 | 3 | | 1995 | 2 | 2 | 4 | | 1996 | 1 | 3 | 4 | | 1997 | 0 | 2 | 2 | | 1998 | 1 | 1 | 2 | | 1999 | 1 | 2 | 3 | | 2000 | 1 | 1 | 2 | | 2001 | 0 | 5 | 5 | | 2002 | 4 | 8 | 12 | | 2003 | 7 | 8 | 15 | | 2004 | 7 | 13 | 20 | | 2005 | 8 | 8 | 16 | | 2006 | 5 | 9 | 14 | | 2007 | 2 | 10 | 12 | | 2008 | 5 | 12 | 17 | | 2009 | 5 | 13 | 18 | | 2010 | 2 | 16 | 18 | | 2011 | 5 | 16 | 21 | | 2012 | 4 | 21 | 25 | | 2013 | 3 | 22 | 25 | | 2014 | 0 | 17 | 17 | | 2015 | 5 | 7 | 12 | | 2016 | 4 | 14 | 18 | | 2017 | 5 | 11 | 16 | | 2018 | 0 | 14 | 14 | | 2019 | 0 | 22 | 22 | | 2020 | 3 | 10 | 13 | | 2021 | 0 | 17 | 17 | | 2022 | 0 | 7 | 7 |
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Below are the most recent publications written about "Reactive Oxygen Species" by people in Profiles.
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Kim JS, Liu L, Davenport B, Kant S, Morrison TE, Vazquez-Torres A. Oxidative stress activates transcription of Salmonella pathogenicity island-2 genes in macrophages. J Biol Chem. 2022 07; 298(7):102130.
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Madhavan K, Balakrishnan I, Lakshmanachetty S, Pierce A, Sanford B, Fosmire S, Elajaili HB, Walker F, Wang D, Nozik ES, Mitra SS, Dahl NA, Vibhakar R, Venkataraman S. Venetoclax Cooperates with Ionizing Radiation to Attenuate Diffuse Midline Glioma Tumor Growth. Clin Cancer Res. 2022 06 01; 28(11):2409-2424.
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Song A, Wen AQ, Wen YE, Dzieciatkowska M, Kellems RE, Juneja HS, D'Alessandro A, Xia Y. p97 dysfunction underlies a loss of quality control of damaged membrane proteins and promotes oxidative stress and sickling in sickle cell disease. FASEB J. 2022 05; 36(5):e22246.
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Crist SB, Nemkov T, Dumpit RF, Dai J, Tapscott SJ, True LD, Swarbrick A, Sullivan LB, Nelson PS, Hansen KC, Ghajar CM. Unchecked oxidative stress in skeletal muscle prevents outgrowth of disseminated tumour cells. Nat Cell Biol. 2022 04; 24(4):538-553.
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Ghosh JC, Perego M, Agarwal E, Bertolini I, Wang Y, Goldman AR, Tang HY, Kossenkov AV, Landis CJ, Languino LR, Plow EF, Morotti A, Ottobrini L, Locatelli M, Speicher DW, Caino MC, Cassel J, Salvino JM, Robert ME, Vaira V, Altieri DC. Ghost mitochondria drive metastasis through adaptive GCN2/Akt therapeutic vulnerability. Proc Natl Acad Sci U S A. 2022 02 22; 119(8).
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Thompson B, Davidson EA, Chen Y, Orlicky DJ, Thompson DC, Vasiliou V. Oxidative stress induces inflammation of lens cells and triggers immune surveillance of ocular tissues. Chem Biol Interact. 2022 Mar 01; 355:109804.
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Ojha R, Tantray I, Rimal S, Mitra S, Cheshier S, Lu B. Regulation of reverse electron transfer at mitochondrial complex I by unconventional Notch action in cancer stem cells. Dev Cell. 2022 01 24; 57(2):260-276.e9.
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Flores-Bellver M, Mighty J, Aparicio-Domingo S, Li KV, Shi C, Zhou J, Cobb H, McGrath P, Michelis G, Lenhart P, Bilousova G, Heissel S, Rudy MJ, Coughlan C, Goodspeed AE, Becerra SP, Redenti S, Canto-Soler MV. Extracellular vesicles released by human retinal pigment epithelium mediate increased polarised secretion of drusen proteins in response to AMD stressors. J Extracell Vesicles. 2021 11; 10(13):e12165.
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D'Alessandro A, Hay A, Dzieciatkowska M, Brown BC, Morrison EJ, Hansen KC, Zimring JC. Protein-L-isoaspartate O-methyltransferase is required for in vivo control of oxidative damage in red blood cells. Haematologica. 2021 10 01; 106(10):2726-2739.
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Salnikova D, Orekhova V, Grechko A, Starodubova A, Bezsonov E, Popkova T, Orekhov A. Mitochondrial Dysfunction in Vascular Wall Cells and Its Role in Atherosclerosis. Int J Mol Sci. 2021 Aug 20; 22(16).
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