Pyruvate Carboxylase
"Pyruvate Carboxylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A biotin-dependent enzyme belonging to the ligase family that catalyzes the addition of CARBON DIOXIDE to pyruvate. It is occurs in both plants and animals. Deficiency of this enzyme causes severe psychomotor retardation and ACIDOSIS, LACTIC in infants. EC 6.4.1.1.
| Descriptor ID |
D011766
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| MeSH Number(s) |
D08.811.464.257.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pyruvate Carboxylase".
Below are MeSH descriptors whose meaning is more specific than "Pyruvate Carboxylase".
This graph shows the total number of publications written about "Pyruvate Carboxylase" by people in this website by year, and whether "Pyruvate Carboxylase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pyruvate Carboxylase" by people in Profiles.
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Whiteley AT, Garelis NE, Peterson BN, Choi PH, Tong L, Woodward JJ, Portnoy DA. c-di-AMP modulates Listeria monocytogenes central metabolism to regulate growth, antibiotic resistance and osmoregulation. Mol Microbiol. 2017 04; 104(2):212-233.
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Willis WT, Jackman MR, Bizeau ME, Pagliassotti MJ, Hazel JR. Hyperthermia impairs liver mitochondrial function in vitro. Am J Physiol Regul Integr Comp Physiol. 2000 May; 278(5):R1240-6.