 Metalloproteases
"Metalloproteases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteases which use a metal, normally ZINC, in the catalytic mechanism. This group of enzymes is inactivated by metal CHELATORS.
| Descriptor ID |
D045726
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| MeSH Number(s) |
D08.811.277.656.675
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Metalloproteases".
Below are MeSH descriptors whose meaning is more specific than "Metalloproteases".
This graph shows the total number of publications written about "Metalloproteases" by people in this website by year, and whether "Metalloproteases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 | | 2005 | 1 | 1 | 2 | | 2006 | 1 | 2 | 3 | | 2007 | 1 | 1 | 2 | | 2008 | 2 | 0 | 2 | | 2010 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 2 | 1 | 3 | | 2017 | 2 | 1 | 3 | | 2019 | 1 | 0 | 1 | | 2020 | 1 | 1 | 2 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Metalloproteases" by people in Profiles.
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Ambardekar AV, Weiser-Evans MCM, McKinsey TA. Arterial wall rejuvenation: the potential of targeting matrix metalloprotease 2 to treat vascular aging. Cardiovasc Res. 2022 07 27; 118(10):2229-2230.
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Bunker EN, Wheeler GE, Chapnick DA, Liu X. Suppression of a-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-a autocrine/paracrine signaling. Mol Biol Cell. 2021 02 15; 32(4):348-361.
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Schilcher K, Caesar LK, Cech NB, Horswill AR. Processing, Export, and Identification of Novel Linear Peptides from Staphylococcus aureus. mBio. 2020 04 14; 11(2).
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Jones BK, Saviola AJ, Reilly SB, Stubbs AL, Arida E, Iskandar DT, McGuire JA, Yates JR, Mackessy SP. Venom Composition in a Phenotypically Variable Pit Viper ( Trimeresurus insularis) across the Lesser Sunda Archipelago. J Proteome Res. 2019 05 03; 18(5):2206-2220.
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Wichert R, Ermund A, Schmidt S, Schweinlin M, Ksiazek M, Arnold P, Knittler K, Wilkens F, Potempa B, Rabe B, Stirnberg M, Lucius R, Bartsch JW, Nikolaus S, Falk-Paulsen M, Rosenstiel P, Metzger M, Rose-John S, Potempa J, Hansson GC, Dempsey PJ, Becker-Pauly C. Mucus Detachment by Host Metalloprotease Meprin ß Requires Shedding of Its Inactive Pro-form, which Is Abrogated by the Pathogenic Protease RgpB. Cell Rep. 2017 Nov 21; 21(8):2090-2103.
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Saviola AJ, Gandara AJ, Bryson RW, Mackessy SP. Venom phenotypes of the Rock Rattlesnake (Crotalus lepidus) and the Ridge-nosed Rattlesnake (Crotalus willardi) from México and the United States. Toxicon. 2017 Nov; 138:119-129.
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Lauinger L, Li J, Shostak A, Cemel IA, Ha N, Zhang Y, Merkl PE, Obermeyer S, Stankovic-Valentin N, Schafmeier T, Wever WJ, Bowers AA, Carter KP, Palmer AE, Tschochner H, Melchior F, Deshaies RJ, Brunner M, Diernfellner A. Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases. Nat Chem Biol. 2017 Jul; 13(7):709-714.
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Borengasser SJ, Faske J, Kang P, Blackburn ML, Badger TM, Shankar K. In utero exposure to prepregnancy maternal obesity and postweaning high-fat diet impair regulators of mitochondrial dynamics in rat placenta and offspring. Physiol Genomics. 2014 Dec 01; 46(23):841-50.
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Caceres SM, Malcolm KC, Taylor-Cousar JL, Nichols DP, Saavedra MT, Bratton DL, Moskowitz SM, Burns JL, Nick JA. Enhanced in vitro formation and antibiotic resistance of nonattached Pseudomonas aeruginosa aggregates through incorporation of neutrophil products. Antimicrob Agents Chemother. 2014 Nov; 58(11):6851-60.
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Pereira FV, Ferreira-Guimarães CA, Paschoalin T, Scutti JA, Melo FM, Silva LS, Melo AC, Silva P, Tiago M, Matsuo AL, Juliano L, Juliano MA, Carmona AK, Travassos LR, Rodrigues EG. A natural bacterial-derived product, the metalloprotease arazyme, inhibits metastatic murine melanoma by inducing MMP-8 cross-reactive antibodies. PLoS One. 2014; 9(4):e96141.
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