 Mutation
"Mutation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
| Descriptor ID |
D009154
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| MeSH Number(s) |
G05.365.590
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Mutation".
Below are MeSH descriptors whose meaning is more specific than "Mutation".
This graph shows the total number of publications written about "Mutation" by people in this website by year, and whether "Mutation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 4 | 16 | 20 | | 1997 | 7 | 20 | 27 | | 1998 | 15 | 20 | 35 | | 1999 | 3 | 24 | 27 | | 2000 | 10 | 34 | 44 | | 2001 | 7 | 44 | 51 | | 2002 | 15 | 40 | 55 | | 2003 | 12 | 60 | 72 | | 2004 | 11 | 54 | 65 | | 2005 | 8 | 62 | 70 | | 2006 | 13 | 67 | 80 | | 2007 | 32 | 53 | 85 | | 2008 | 31 | 64 | 95 | | 2009 | 19 | 66 | 85 | | 2010 | 21 | 72 | 93 | | 2011 | 25 | 69 | 94 | | 2012 | 36 | 75 | 111 | | 2013 | 36 | 90 | 126 | | 2014 | 42 | 100 | 142 | | 2015 | 53 | 86 | 139 | | 2016 | 45 | 120 | 165 | | 2017 | 34 | 121 | 155 | | 2018 | 52 | 109 | 161 | | 2019 | 47 | 120 | 167 | | 2020 | 31 | 90 | 121 | | 2021 | 28 | 118 | 146 | | 2022 | 5 | 129 | 134 | | 2023 | 1 | 94 | 95 | | 2024 | 27 | 65 | 92 | | 2025 | 28 | 76 | 104 | | 2026 | 3 | 15 | 18 |
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Below are the most recent publications written about "Mutation" by people in Profiles.
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Wooten E, Chon NL, Dzhalolov M, Zheng H, Lin H. Protonation States of Proton-Sensing Glutamate Residues in Transporter Sialin. Int J Mol Sci. 2026 May 21; 27(10).
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Sekrecki M, Sekrecka A, Lattupally RR, Le K, Jin X, Mozes C, Dwyer BG, Zhuang Z, Romero BA, Pineda JMB, Cao X, Nguyen L, Chen V, Zhou CM, Wallace JA, Tanaka K, Tiwari C, Gabel A, Kim WJ, Stanley RF, Benbarche S, Thind J, Muruganandham A, Zhang TY, Greenberg PL, Gotlib JR, Mannis G, Shomali WE, Salmasi G, Kuo C, Shanafelt T, Singh I, Inoue D, Hansen FK, Gray NS, van Rechem C, Fakhri B, Zhang X, Lu SX. Oncogenic SF3B1 mutations alter the splicing of mRNA noncoding regions to induce a novel therapeutic vulnerability. Blood. 2026 Apr 23; 147(17):1941-1957.
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Erdem S, Haliloglu Y, Uslu IN, Houran M, Ulutabanca H, Vural A, Erturhan MB, Canatan H, Eken A. IDH1 Mutant Glioma Favors Group 3 Innate Lymphoid Cells and Is Resistant to Immune Checkpoint Expression. Inflamm Res. 2026 Apr 01; 75(1).
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Waliany S, Cooper AJ, Liu SV, Gautschi O, Rotow JK, Smith KER, Weber UM, Lee DH, Loong HHF, Patel JD, Pennell NA, Nagasaka M, Patel SA, Tan DSW, Solomon BJ, Kim TM, Pall G, Riess JW, Sun L, Früh M, Uy NF, Gadgeel S, Feng J, Do A, Falcon C, Leighl NB, Baik CS, Lai GGY, Ou SI, Cheung KSY, Patil T, Mansfield AS, Weiler D, Yeap BY, Wirth LJ, Gainor JF, Drilon A, Lin JJ. Landscape of Genomic Mechanisms of Resistance to Selective RET Inhibitors in RET-Altered Solid Tumors: Analysis of the RETgistry Global Consortium. Clin Cancer Res. 2026 Mar 16; 32(6):1157-1168.
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Collier AE, Hilz S, Chibly AM, Duan C, Pasquina LW, Sun X, Chavez-MacGregor M, Bardia A, Martín M, Lim E, Sohn J, Pérez-Moreno PD, Fernando TM, Moore HM. ctDNA and tumor-based biomarkers of giredestrant response in acelERA breast cancer. Nat Commun. 2026 Mar 12; 17(1).
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Fountzilas C, Rosario S, Witkiewicz AK, Withers HG, Bajor DL, Mukherjee S, Saltzman J, Maguire O, Minderman H, Chatley S, Tarquini ML, Whitworth A, Jurcevic J, Hsiao HH, Knudsen ES, Muhitch JB, Abrams SI, Kalinski P, Segal BH, Bakin A, Yuan G, Wang C, Attwood K, Iyer R, Boland PM. TP53 mutation is associated with improved disease control in patients with advanced RAS wild-type colorectal adenocarcinoma treated with cetuximab and pembrolizumab. Int J Cancer. 2026 Jun 15; 158(12):3300-3311.
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Nassour J, Karlseder J. Telomere Crisis Shapes Cancer Evolution. Cold Spring Harb Perspect Biol. 2026 Mar 02; 18(3).
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Wang K, Saniei S, Poddar N, Martinez IG, Chao C, Autar S, Fiore P, Carcamo S, Sreenath M, Peplinski JH, Ries RE, Mei AH, Rahman NA, Mekerishvili L, Quijada-Álamo M, Freed G, Zhang M, Lachman K, Diaz Z, Gonzalez MM, Zhang J, Pham G, Filipescu D, Berisa M, Balestra T, Wheeler N, Reisz JA, D'Alessandro A, Puleston DJ, Bernstein E, Chipuk JE, Wunderlich M, Tasian SK, Marcellino BK, Glass IA, Sturgeon CM, Landau DA, Chen Z, Papapetrou EP, Izzo F, Meshinchi S, Hasson D, Wagenblast E. Ontogeny Dictates Oncogenic Potential, Lineage Hierarchy, and Therapy Response in Pediatric Leukemia. Cancer Discov. 2026 Mar 02; 16(3):541-570.
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Dermawan JK, Vanoli F, de Traux de Wardin H, Levi JN, Sanchez GI, Siddiquee A, Brosius S, You D, Tirode F, Sung P, Karanian M, Pissaloux D, Wexler LH, Kung A, Soragni A, Dela Cruz FS, Pavisic J, Antonescu CR. Single-cell protein activity analysis reveals aberrant myogenesis and IGF2-PI3K pathway dependencies in MYOD1-mutant rhabdomyosarcoma. Sci Adv. 2026 02 27; 12(9):eaea6453.
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Martin-Martin A, Chipón C, Guzman-Kunstmann C, Guzman-Kunstmann S, Buelvas N, Henríquez C, Vidal F, Villarroel-Espindola F, Hinz TK, Heasley LE, López-Muñoz RA. The polyamine inhibitor SAM486A increases the efficacy of adagrasib in non-small cell lung cancer cells harboring KRASG12C mutation. Biol Res. 2026 Feb 19; 59(1).
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