Kynurenic Acid
"Kynurenic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A broad-spectrum excitatory amino acid antagonist used as a research tool.
Descriptor ID |
D007736
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MeSH Number(s) |
D03.066.942.505 D03.633.100.810.350.400
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Kynurenic Acid".
Below are MeSH descriptors whose meaning is more specific than "Kynurenic Acid".
This graph shows the total number of publications written about "Kynurenic Acid" by people in this website by year, and whether "Kynurenic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 | 2005 | 0 | 2 | 2 | 2014 | 0 | 1 | 1 | 2016 | 0 | 1 | 1 | 2017 | 0 | 1 | 1 | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Kynurenic Acid" by people in Profiles.
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Nahomi RB, Nam MH, Rankenberg J, Rakete S, Houck JA, Johnson GC, Stankowska DL, Pantcheva MB, MacLean PS, Nagaraj RH. Kynurenic Acid Protects Against Ischemia/Reperfusion-Induced Retinal Ganglion Cell Death in Mice. Int J Mol Sci. 2020 Mar 05; 21(5).
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Bortz DM, Wu HQ, Schwarcz R, Bruno JP. Oral administration of a specific kynurenic acid synthesis (KAT II) inhibitor attenuates evoked glutamate release in rat prefrontal cortex. Neuropharmacology. 2017 Jul 15; 121:69-78.
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Coccaro EF, Lee R, Fanning JR, Fuchs D, Goiny M, Erhardt S, Christensen K, Brundin L, Coussons-Read M. Tryptophan, kynurenine, and kynurenine metabolites: Relationship to lifetime aggression and inflammatory markers in human subjects. Psychoneuroendocrinology. 2016 09; 71:189-96.
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Pershing ML, Bortz DM, Pocivavsek A, Fredericks PJ, J?rgensen CV, Vunck SA, Leuner B, Schwarcz R, Bruno JP. Elevated levels of kynurenic acid during gestation produce neurochemical, morphological, and cognitive deficits in adulthood: implications for schizophrenia. Neuropharmacology. 2015 Mar; 90:33-41.
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Prescott C, Weeks AM, Staley KJ, Partin KM. Kynurenic acid has a dual action on AMPA receptor responses. Neurosci Lett. 2006 Jul 10; 402(1-2):108-12.
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Cathala L, Holderith NB, Nusser Z, DiGregorio DA, Cull-Candy SG. Changes in synaptic structure underlie the developmental speeding of AMPA receptor-mediated EPSCs. Nat Neurosci. 2005 Oct; 8(10):1310-8.
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Sargent PB, Saviane C, Nielsen TA, DiGregorio DA, Silver RA. Rapid vesicular release, quantal variability, and spillover contribute to the precision and reliability of transmission at a glomerular synapse. J Neurosci. 2005 Sep 07; 25(36):8173-87.
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DiGregorio DA, Nusser Z, Silver RA. Spillover of glutamate onto synaptic AMPA receptors enhances fast transmission at a cerebellar synapse. Neuron. 2002 Aug 01; 35(3):521-33.
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Hoffman PL, Iorio KR, Snell LD, Tabakoff B. Attenuation of glutamate-induced neurotoxicity in chronically ethanol-exposed cerebellar granule cells by NMDA receptor antagonists and ganglioside GM1. Alcohol Clin Exp Res. 1995 Jun; 19(3):721-6.
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Sladek CD, Fisher KY, Sidorowicz HE, Mathiasen JR. Osmotic stimulation of vasopressin mRNA content in the supraoptic nucleus requires synaptic activation. Am J Physiol. 1995 Apr; 268(4 Pt 2):R1034-9.
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