 CADASIL
"CADASIL" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A familial, cerebral arteriopathy mapped to chromosome 19q12, and characterized by the presence of granular deposits in small CEREBRAL ARTERIES producing ischemic STROKE; PSEUDOBULBAR PALSY; and multiple subcortical infarcts (CEREBRAL INFARCTION). CADASIL is an acronym for Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy. CADASIL differs from BINSWANGER DISEASE by the presence of MIGRAINE WITH AURA and usually by the lack of history of arterial HYPERTENSION. (From Bradley et al, Neurology in Clinical Practice, 2000, p1146)
| Descriptor ID |
D046589
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| MeSH Number(s) |
C10.228.140.300.275.249 C10.228.140.300.400.203 C10.228.140.300.510.200.175 C10.228.140.380.230.124 C14.907.253.329.249 C14.907.253.560.200.175 C16.320.129
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| Concept/Terms |
CADASIL- CADASIL
- Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
- Dementia, Hereditary Multi-Infarct Type
- Dementia, Hereditary Multi Infarct Type
- Cerebral Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
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Below are MeSH descriptors whose meaning is more general than "CADASIL".
Below are MeSH descriptors whose meaning is more specific than "CADASIL".
This graph shows the total number of publications written about "CADASIL" by people in this website by year, and whether "CADASIL" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "CADASIL" by people in Profiles.
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Lee YC, Chung CP, Chang MH, Wang SJ, Liao YC. NOTCH3 cysteine-altering variant is an important risk factor for stroke in the Taiwanese population. Neurology. 2020 01 07; 94(1):e87-e96.
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Candelario N, Lo KB. When stroke runs in the family. Cleve Clin J Med. 2018 Oct; 85(10):743-744.
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Koide M, Moshkforoush A, Tsoukias NM, Hill-Eubanks DC, Wellman GC, Nelson MT, Dabertrand F. The yin and yang of KV channels in cerebral small vessel pathologies. Microcirculation. 2018 01; 25(1).
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Capone C, Dabertrand F, Baron-Menguy C, Chalaris A, Ghezali L, Domenga-Denier V, Schmidt S, Huneau C, Rose-John S, Nelson MT, Joutel A. Mechanistic insights into a TIMP3-sensitive pathway constitutively engaged in the regulation of cerebral hemodynamics. Elife. 2016 08 01; 5.
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Liao YC, Hsiao CT, Fuh JL, Chern CM, Lee WJ, Guo YC, Wang SJ, Lee IH, Liu YT, Wang YF, Chang FC, Chang MH, Soong BW, Lee YC. Characterization of CADASIL among the Han Chinese in Taiwan: Distinct Genotypic and Phenotypic Profiles. PLoS One. 2015; 10(8):e0136501.
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