Bleomycin
"Bleomycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2. It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors.
Descriptor ID |
D001761
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MeSH Number(s) |
D09.400.420.110 D12.644.233.110
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Bleomycin".
Below are MeSH descriptors whose meaning is more specific than "Bleomycin".
This graph shows the total number of publications written about "Bleomycin" by people in this website by year, and whether "Bleomycin" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 | 1996 | 0 | 1 | 1 | 1997 | 1 | 0 | 1 | 1998 | 0 | 1 | 1 | 1999 | 1 | 0 | 1 | 2001 | 0 | 1 | 1 | 2002 | 0 | 2 | 2 | 2003 | 1 | 1 | 2 | 2004 | 1 | 2 | 3 | 2005 | 0 | 2 | 2 | 2006 | 0 | 1 | 1 | 2007 | 0 | 2 | 2 | 2008 | 1 | 1 | 2 | 2009 | 0 | 2 | 2 | 2010 | 0 | 2 | 2 | 2011 | 2 | 3 | 5 | 2012 | 3 | 3 | 6 | 2013 | 1 | 0 | 1 | 2014 | 0 | 4 | 4 | 2015 | 1 | 1 | 2 | 2016 | 1 | 3 | 4 | 2017 | 1 | 3 | 4 | 2018 | 5 | 6 | 11 | 2019 | 2 | 7 | 9 | 2020 | 2 | 6 | 8 | 2021 | 2 | 1 | 3 | 2022 | 0 | 3 | 3 | 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Bleomycin" by people in Profiles.
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Steiner RE, Hwang SR, Khurana A, Habermann TM, Epperla N, Annunzio K, Allen PB, Baird K, Paulino D, Alderuccio JP, Lossos IS, David K, Evens AM, Pandya K, Bair SM, Kamdar M, Ba Aqeel S, Torka P, Lynch R, Smith S, Feng L, Noorani M, Ahmed S, Nair R, Vega F, Wu S, Fang P, Pinnix CC, Gunther JR, Dabaja BS, Lee HJ. Impact of cumulative dose of brentuximab vedotin on outcomes of frontline therapy for advanced-stage Hodgkin lymphoma. Blood Adv. 2023 12 26; 7(24):7485-7493.
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Dobrinskikh E, Hennessy CE, Kurche JS, Kim E, Estrella AM, Cardwell J, Yang IV, Schwartz DA. Epithelial Endoplasmic Reticulum Stress Enhances the Risk of Muc5b-associated Lung Fibrosis. Am J Respir Cell Mol Biol. 2023 01; 68(1):62-74.
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Ahangari F, Becker C, Foster DG, Chioccioli M, Nelson M, Beke K, Wang X, Justet A, Adams T, Readhead B, Meador C, Correll K, Lili LN, Roybal HM, Rose KA, Ding S, Barnthaler T, Briones N, DeIuliis G, Schupp JC, Li Q, Omote N, Aschner Y, Sharma L, Kopf KW, Magnusson B, Hicks R, Backmark A, Dela Cruz CS, Rosas I, Cousens LP, Dudley JT, Kaminski N, Downey GP. Saracatinib, a Selective Src Kinase Inhibitor, Blocks Fibrotic Responses in Preclinical Models of Pulmonary Fibrosis. Am J Respir Crit Care Med. 2022 12 15; 206(12):1463-1479.
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Kurche JS, Stancil IT, Michalski JE, Yang IV, Schwartz DA. Dysregulated Cell-Cell Communication Characterizes Pulmonary Fibrosis. Cells. 2022 10 21; 11(20).
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Kim E, Mathai SK, Stancil IT, Ma X, Hernandez-Gutierrez A, Becerra JN, Marrero-Torres E, Hennessy CE, Hatakka K, Wartchow EP, Estrella A, Huber JP, Cardwell JH, Burnham EL, Zhang Y, Evans CM, Vladar EK, Schwartz DA, Dobrinskikh E, Yang IV. Aberrant Multiciliogenesis in Idiopathic Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2022 08; 67(2):188-200.
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Dobrinskikh E, Estrella AM, Hennessy CE, Hara N, Schwarz MI, Kurche JS, Yang IV, Schwartz DA. Genes, other than Muc5b, play a role in bleomycin-induced lung fibrosis. Am J Physiol Lung Cell Mol Physiol. 2021 08 01; 321(2):L440-L450.
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Redente EF, Black BP, Backos DS, Bahadur AN, Humphries SM, Lynch DA, Tuder RM, Zemans RL, Riches DWH. Persistent, Progressive Pulmonary Fibrosis and Epithelial Remodeling in Mice. Am J Respir Cell Mol Biol. 2021 06; 64(6):669-676.
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Niemiec SM, Hilton SA, Wallbank A, Azeltine M, Louiselle AE, Elajaili H, Allawzi A, Xu J, Mattson C, Dewberry LC, Hu J, Singh S, Sakthivel TS, Sea S, Nozik-Grayck E, Smith B, Zgheib C, Liechty KW. Cerium oxide nanoparticle delivery of microRNA-146a for local treatment of acute lung injury. Nanomedicine. 2021 06; 34:102388.
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Redente EF, Chakraborty S, Sajuthi S, Black BP, Edelman BL, Seibold MA, Riches DW. Loss of Fas signaling in fibroblasts impairs homeostatic fibrosis resolution and promotes persistent pulmonary fibrosis. JCI Insight. 2020 12 08; 6(1).
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Pinnix CC, Gunther JR, Fang P, Bankston ME, Milgrom SA, Boyce D, Lee HJ, Nair R, Steiner R, Strati P, Ahmed S, Iyer SP, Westin J, Parmar S, Rodriguez MA, Nastoupil L, Neelapu S, Flowers C, Dabaja BS. Assessment of Radiation Doses Delivered to Organs at Risk Among Patients With Early-Stage Favorable Hodgkin Lymphoma Treated With Contemporary Radiation Therapy. JAMA Netw Open. 2020 09 01; 3(9):e2013935.
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