 Caspase 8
"Caspase 8" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A long pro-domain caspase that contains a death effector domain in its pro-domain region. Caspase 8 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS.
| Descriptor ID |
D053181
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| MeSH Number(s) |
D08.811.277.656.262.500.126.550.800 D08.811.277.656.300.200.126.550.800 D12.644.360.024.285.037 D12.644.360.075.405.550.800 D12.644.360.075.421.037 D12.776.157.057.018.037 D12.776.476.024.320.025 D12.776.476.075.405.550.800 D12.776.476.075.421.037
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| Concept/Terms |
Caspase 8- Caspase 8
- FLICE Protein
- Mch5 Protease
- Caspase-8
- CAP4 Protease
- MACH Protein
Procaspase-8- Procaspase-8
- Procaspase 8
- Pro-Caspase-8
- Pro Caspase 8
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Below are MeSH descriptors whose meaning is more general than "Caspase 8".
Below are MeSH descriptors whose meaning is more specific than "Caspase 8".
This graph shows the total number of publications written about "Caspase 8" by people in this website by year, and whether "Caspase 8" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2003 | 0 | 3 | 3 | | 2004 | 0 | 5 | 5 | | 2005 | 0 | 5 | 5 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 1 | 2 | | 2009 | 1 | 2 | 3 | | 2010 | 0 | 1 | 1 | | 2011 | 1 | 1 | 2 | | 2012 | 0 | 2 | 2 | | 2013 | 0 | 2 | 2 | | 2015 | 0 | 2 | 2 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Caspase 8" by people in Profiles.
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Mukherjee AK, Saviola AJ, Mackessy SP. Cellular mechanism of resistance of human colorectal adenocarcinoma cells against apoptosis-induction by Russell's Viper venom l-amino acid oxidase (Rusvinoxidase). Biochimie. 2018 Jul; 150:8-15.
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Alves da Costa T, Di Gangi R, Thom? R, Barreto Felisbino M, Pires Bonfanti A, Lumi Watanabe Ishikawa L, Sartori A, Burger E, Verinaud L. Severe Changes in Thymic Microenvironment in a Chronic Experimental Model of Paracoccidioidomycosis. PLoS One. 2016; 11(10):e0164745.
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Milanovic D, Pesic V, Loncarevic-Vasiljkovic N, Pavkovic Z, Popic J, Kanazir S, Jevtovic-Todorovic V, Ruzdijic S. The Fas Ligand/Fas Death Receptor Pathways Contribute to Propofol-Induced Apoptosis and Neuroinflammation in the Brain of Neonatal Rats. Neurotox Res. 2016 10; 30(3):434-52.
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Heinhuis B, Plantinga TS, Semango G, K?sters B, Netea MG, Dinarello CA, Smit JWA, Netea-Maier RT, Joosten LAB. Alternatively spliced isoforms of IL-32 differentially influence cell death pathways in cancer cell lines. Carcinogenesis. 2016 Feb; 37(2):197-205.
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Sullivan KD, Palaniappan VV, Espinosa JM. ATM regulates cell fate choice upon p53 activation by modulating mitochondrial turnover and ROS levels. Cell Cycle. 2015; 14(1):56-63.
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Clarke P, Leser JS, Quick ED, Dionne KR, Beckham JD, Tyler KL. Death receptor-mediated apoptotic signaling is activated in the brain following infection with West Nile virus in the absence of a peripheral immune response. J Virol. 2014 Jan; 88(2):1080-9.
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Carter SR, Zahs A, Palmer JL, Wang L, Ramirez L, Gamelli RL, Kovacs EJ. Intestinal barrier disruption as a cause of mortality in combined radiation and burn injury. Shock. 2013 Oct; 40(4):281-9.
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Arruda DC, Santos LC, Melo FM, Pereira FV, Figueiredo CR, Matsuo AL, Mortara RA, Juliano MA, Rodrigues EG, Dobroff AS, Polonelli L, Travassos LR. ?-Actin-binding complementarity-determining region 2 of variable heavy chain from monoclonal antibody C7 induces apoptosis in several human tumor cells and is protective against metastatic melanoma. J Biol Chem. 2012 Apr 27; 287(18):14912-22.
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Henry RE, Andrysik Z, Par?s R, Galbraith MD, Espinosa JM. A DR4:tBID axis drives the p53 apoptotic response by promoting oligomerization of poised BAX. EMBO J. 2012 Mar 07; 31(5):1266-78.
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Janssen WJ, Barthel L, Muldrow A, Oberley-Deegan RE, Kearns MT, Jakubzick C, Henson PM. Fas determines differential fates of resident and recruited macrophages during resolution of acute lung injury. Am J Respir Crit Care Med. 2011 Sep 01; 184(5):547-60.
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